CAZyme Information: PIS56397.1

Basic Information

• Species: [Candida] auris
• Lineage: Ascomycota; Saccharomycetes; ; Debaryomycetaceae; Candida; [Candida] auris
• CAZyme ID: PIS56397.1
• CAZy Family: GT39
• CAZyme Description: unspecified product

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
566		63615.41	4.5613

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_CaurisB11221	5715	N/A	194	5521

• Gene Location: location=PGLS01000002:1267561-1269261(-)

Full Sequence      

MHEVYLWPFADVIKAGVGGIMCAYNMVNNTYACENSQLLNYLLKEELAFQGFVVSDWGAQ
HTGVTSALSGLDMTMPGEVFDDWLGGKSYWGPLLTRAVYNKTIPQDRLNDMAARILAPFF
SSEHLSLPSCEEVPNFSSWTHHTYGQQYPYQHFGAIVQQNFHAEARSVMNDKVALETARQ
GIVLLKNKNRNLPIHKDDGVRRLLIAGIAGGVDPNGFNCRDQKCTDGTLTSGWGSASVNN
PWVVTAQEAISRKARERGMLVDLSEDNWDLECTEELSDFADMTIVIVNSVSGEGYIEVDY
NYGDRNNVSLWHNGDELIKRVTEGCKKTVVVINAVGPVNMEKWIENDNVVAVLFVPPLGQ
FVGVAIAEVLFGEVNPSGKLPFTIAKKNSHYADIRYELGDCCDPQDTFEKGVYLDYRFFD
KHNIKPRFEFGYGLSYSKFSVTDLEIYEINPPSEYLPCPSDYMPRFHTIEDDICDPEDAL
FPHDEMDPVPGFIYPYLYNEDVRSLDEDDCYDYPKGYTPDQKCEAPLAGGGPGGNPALRE
IEEKREKKKEKKSNNLGYIQKRNSGS

Enzyme Prediction     

No EC number prediction in PIS56397.1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH3	1	76	8.1e-23	0.37962962962962965

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
396478	Glyco_hydro_3_C	1.61e-42	182	416	1	216	Glycosyl hydrolase family 3 C-terminal domain. This domain is involved in catalysis and may be involved in binding beta-glucan. This domain is found associated with pfam00933.
185053	PRK15098	5.87e-30	1	444	232	656	beta-glucosidase BglX.
178629	PLN03080	6.53e-21	1	440	242	637	Probable beta-xylosidase; Provisional
395747	Glyco_hydro_3	2.56e-10	1	116	196	314	Glycosyl hydrolase family 3 N terminal domain.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QWW22787.1|GH3	0.0	1	540	173	712
QRG35807.1|GH3	0.0	1	540	173	712
QEL59728.1|GH3	0.0	1	540	173	712
QWU85892.1|GH3	0.0	1	540	876	1415
SGZ52688.1|GH3	2.28e-301	1	541	195	735

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4IIB_A	1.55e-129	1	538	206	739	Crystal structure of beta-glucosidase 1 from Aspergillus aculeatus [Aspergillus aculeatus],4IIB_B Crystal structure of beta-glucosidase 1 from Aspergillus aculeatus [Aspergillus aculeatus],4IIC_A Crystal structure of beta-glucosidase 1 from Aspergillus aculeatus in complex with isofagomine [Aspergillus aculeatus],4IIC_B Crystal structure of beta-glucosidase 1 from Aspergillus aculeatus in complex with isofagomine [Aspergillus aculeatus],4IID_A Crystal structure of beta-glucosidase 1 from Aspergillus aculeatus in complex with 1-deoxynojirimycin [Aspergillus aculeatus],4IID_B Crystal structure of beta-glucosidase 1 from Aspergillus aculeatus in complex with 1-deoxynojirimycin [Aspergillus aculeatus],4IIE_A Crystal structure of beta-glucosidase 1 from Aspergillus aculeatus in complex with calystegine B(2) [Aspergillus aculeatus],4IIE_B Crystal structure of beta-glucosidase 1 from Aspergillus aculeatus in complex with calystegine B(2) [Aspergillus aculeatus],4IIF_A Crystal structure of beta-glucosidase 1 from Aspergillus aculeatus in complex with castanospermine [Aspergillus aculeatus],4IIF_B Crystal structure of beta-glucosidase 1 from Aspergillus aculeatus in complex with castanospermine [Aspergillus aculeatus],4IIG_A Crystal structure of beta-glucosidase 1 from Aspergillus aculeatus in complex with D-glucose [Aspergillus aculeatus],4IIG_B Crystal structure of beta-glucosidase 1 from Aspergillus aculeatus in complex with D-glucose [Aspergillus aculeatus],4IIH_A Crystal structure of beta-glucosidase 1 from Aspergillus aculeatus in complex with thiocellobiose [Aspergillus aculeatus],4IIH_B Crystal structure of beta-glucosidase 1 from Aspergillus aculeatus in complex with thiocellobiose [Aspergillus aculeatus]
6SZ6_A	3.81e-129	1	541	201	740	Chain A, Beta-glucosidase [Thermochaetoides thermophila]
5FJJ_A	5.25e-127	1	540	207	742	Three-dimensional structures of two heavily N-glycosylated Aspergillus sp. Family GH3 beta-D-glucosidases [Aspergillus oryzae],5FJJ_B Three-dimensional structures of two heavily N-glycosylated Aspergillus sp. Family GH3 beta-D-glucosidases [Aspergillus oryzae],5FJJ_C Three-dimensional structures of two heavily N-glycosylated Aspergillus sp. Family GH3 beta-D-glucosidases [Aspergillus oryzae],5FJJ_D Three-dimensional structures of two heavily N-glycosylated Aspergillus sp. Family GH3 beta-D-glucosidases [Aspergillus oryzae]
5FJI_A	7.06e-124	1	538	207	742	Three-dimensional structures of two heavily N-glycosylated Aspergillus sp. Family GH3 beta-D-glucosidases [Aspergillus fumigatus],5FJI_B Three-dimensional structures of two heavily N-glycosylated Aspergillus sp. Family GH3 beta-D-glucosidases [Aspergillus fumigatus]
5JU6_A	1.59e-121	1	540	222	755	Chain A, Beta-glucosidase [Rasamsonia emersonii],5JU6_B Chain B, Beta-glucosidase [Rasamsonia emersonii],5JU6_C Chain C, Beta-glucosidase [Rasamsonia emersonii],5JU6_D Chain D, Beta-glucosidase [Rasamsonia emersonii]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P22506|BGL1_SACFI	7.12e-167	1	541	240	777	Beta-glucosidase 1 OS=Saccharomycopsis fibuligera OX=4944 GN=BGL1 PE=3 SV=1
sp|P22507|BGL2_SACFI	8.89e-166	1	544	244	784	Beta-glucosidase 2 OS=Saccharomycopsis fibuligera OX=4944 GN=BGL2 PE=3 SV=1
sp|P06835|BGLS_WICAO	6.70e-134	1	535	244	761	Beta-glucosidase OS=Wickerhamomyces anomalus OX=4927 PE=3 SV=1
sp|P87076|BGLA_ASPKW	4.98e-132	1	538	225	758	Beta-glucosidase A OS=Aspergillus kawachii (strain NBRC 4308) OX=1033177 GN=bglA PE=1 SV=2
sp|A2RAL4|BGLA_ASPNC	7.65e-131	1	538	225	758	Probable beta-glucosidase A OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) OX=425011 GN=bglA PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000068	0.000001

TMHMM  Annotations     

There is no transmembrane helices in PIS56397.1.