Species | Phycomyces blakesleeanus | |||||||||||
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Lineage | Mucoromycota; Mucoromycetes; ; Phycomycetaceae; Phycomyces; Phycomyces blakesleeanus | |||||||||||
CAZyme ID | PHYBL_168113T0-p1 | |||||||||||
CAZy Family | GH47 | |||||||||||
CAZyme Description | Dolichyl-phosphate-mannose:protein O-mannosyl transferase | |||||||||||
CAZyme Property |
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Genome Property |
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Gene Location |
EC | 2.4.1.109:12 |
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Family | Start | End | Evalue | family coverage |
---|---|---|---|---|
GT39 | 66 | 304 | 9.3e-39 | 0.9910313901345291 |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
224839 | PMT1 | 1.27e-86 | 39 | 759 | 3 | 687 | Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]. |
396786 | PMT | 1.33e-33 | 64 | 306 | 1 | 243 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
397103 | MIR | 1.89e-19 | 353 | 506 | 1 | 172 | MIR domain. The MIR (protein mannosyltransferase, IP3R and RyR) domain is a domain that may have a ligand transferase function. |
197746 | MIR | 2.92e-07 | 337 | 386 | 4 | 55 | Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases. |
406576 | PMT_4TMC | 4.97e-05 | 596 | 763 | 42 | 198 | C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes. |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
2.25e-177 | 38 | 864 | 20 | 802 | |
1.82e-85 | 33 | 769 | 83 | 791 | |
1.01e-84 | 41 | 759 | 49 | 735 | |
1.01e-84 | 41 | 759 | 49 | 735 | |
2.63e-84 | 41 | 759 | 49 | 735 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
2.36e-69 | 52 | 759 | 42 | 721 | Structure of S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the sugar donor and a peptide acceptor [Saccharomyces cerevisiae W303],6P2R_A Structure of S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the sugar donor [Saccharomyces cerevisiae W303] |
|
3.11e-49 | 57 | 512 | 62 | 517 | Structure of S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the sugar donor and a peptide acceptor [Saccharomyces cerevisiae W303],6P2R_B Structure of S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the sugar donor [Saccharomyces cerevisiae W303] |
|
3.18e-21 | 335 | 512 | 13 | 191 | Structure of the Pmt3-MIR domain with bound ligands [Saccharomyces cerevisiae],6ZQQ_B Structure of the Pmt3-MIR domain with bound ligands [Saccharomyces cerevisiae],6ZQQ_C Structure of the Pmt3-MIR domain with bound ligands [Saccharomyces cerevisiae],6ZQQ_D Structure of the Pmt3-MIR domain with bound ligands [Saccharomyces cerevisiae] |
|
3.44e-12 | 336 | 504 | 17 | 172 | Crystal structure of the SDF2-like protein from Arabidopsis thaliana [Arabidopsis thaliana],3MAL_B Crystal structure of the SDF2-like protein from Arabidopsis thaliana [Arabidopsis thaliana] |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
1.21e-68 | 52 | 759 | 42 | 721 | Dolichyl-phosphate-mannose--protein mannosyltransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=PMT1 PE=1 SV=1 |
|
6.16e-62 | 63 | 551 | 61 | 549 | Protein O-mannosyl-transferase 2 OS=Homo sapiens OX=9606 GN=POMT2 PE=1 SV=2 |
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1.86e-60 | 63 | 551 | 131 | 619 | Protein O-mannosyl-transferase 2 OS=Mus musculus OX=10090 GN=Pomt2 PE=1 SV=1 |
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1.93e-60 | 58 | 756 | 64 | 736 | Dolichyl-phosphate-mannose--protein mannosyltransferase 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=PMT1 PE=2 SV=1 |
|
2.24e-60 | 68 | 759 | 54 | 717 | Dolichyl-phosphate-mannose--protein mannosyltransferase 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=PMT5 PE=1 SV=1 |
Other | SP_Sec_SPI | CS Position |
---|---|---|
0.992206 | 0.007793 |
Start | End |
---|---|
167 | 184 |
194 | 216 |
285 | 307 |
610 | 629 |
724 | 746 |
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