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CAZyme Information: PHPALM_18638-t46_1-p1

You are here: Home > Sequence: PHPALM_18638-t46_1-p1

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Phytophthora palmivora
Lineage Oomycota; NA; ; Peronosporaceae; Phytophthora; Phytophthora palmivora
CAZyme ID PHPALM_18638-t46_1-p1
CAZy Family GH17
CAZyme Description Putative beta-1,4-galactosyltransferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
307 35120.47 6.3837
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_Ppalmivorasbr112.9 28185 N/A 3511 24674
Gene Location

Full Sequence      Download help

Enzyme Prediction      help

EC 2.4.1.-:5

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT7 3 236 1.3e-57 0.868

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
132999 b4GalT 1.22e-58 6 237 3 218
Beta-4-Galactosyltransferase is involved in the formation of the poly-N-acetyllactosamine core structures present in glycoproteins and glycosphingolipids. Beta-4-Galactosyltransferase transfers galactose from uridine diphosphogalactose to the terminal beta-N-acetylglucosamine residues, hereby forming the poly-N-acetyllactosamine core structures present in glycoproteins and glycosphingolipids. At least seven homologous beta-4-galactosyltransferase isoforms have been identified that use different types of glycoproteins and glycolipids as substrates. Of the seven identified members of the beta-1,4-galactosyltransferase subfamily (beta1,4-Gal-T1 to -T7), b1,4-Gal-T1 is most characterized (biochemically). It is a Golgi-resident type II membrane enzyme with a cytoplasmic domain, membrane spanning region, and a stem region and catalytic domain facing the lumen.
397018 Glyco_transf_7C 1.24e-24 106 175 1 71
N-terminal domain of galactosyltransferase. This is the N-terminal domain of a family of galactosyltransferases from a wide range of Metazoa with three related galactosyltransferases activities, all three of which are possessed by one sequence in some cases. EC:2.4.1.90, N-acetyllactosamine synthase; EC:2.4.1.38, Beta-N-acetylglucosaminyl-glycopeptide beta-1,4- galactosyltransferase; and EC:2.4.1.22 Lactose synthase. Note that N-acetyllactosamine synthase is a component of Lactose synthase along with alpha-lactalbumin, in the absence of alpha-lactalbumin EC:2.4.1.90 is the catalyzed reaction.
404599 Glyco_transf_7N 3.31e-20 5 95 47 128
N-terminal region of glycosyl transferase group 7. This is the N-terminal half of a family of galactosyltransferases from a wide range of Metazoa with three related galactosyltransferases activities, all three of which are possessed by one sequence in some cases. EC:2.4.1.90, N-acetyllactosamine synthase; EC:2.4.1.38, Beta-N-acetylglucosaminyl-glycopeptide beta-1,4- galactosyltransferase; and EC:2.4.1.22 Lactose synthase. Note that N-acetyllactosamine synthase is a component of Lactose synthase along with alpha-lactalbumin, in the absence of alpha-lactalbumin EC:2.4.1.90 is the catalyzed reaction.
133042 GT2_Chondriotin_Pol_N 1.50e-06 125 161 128 164
N-terminal domain of Chondroitin polymerase functions as a GalNAc transferase. Chondroitin polymerase is a two domain, bi-functional protein. The N-terminal domain functions as a GalNAc transferase. The bacterial chondroitin polymerase catalyzes elongation of the chondroitin chain by alternatively transferring the GlcUA and GalNAc moiety from UDP-GlcUA and UDP-GalNAc to the non-reducing ends of the chondroitin chain. The enzyme consists of N-terminal and C-terminal domains in which the two active sites catalyze the addition of GalNAc and GlcUA, respectively. Chondroitin chains range from 40 to over 100 repeating units of the disaccharide. Sulfated chondroitins are involved in the regulation of various biological functions such as central nervous system development, wound repair, infection, growth factor signaling, and morphogenesis, in addition to its conventional structural roles. In Caenorhabditis elegans, chondroitin is an essential factor for the worm to undergo cytokinesis and cell division. Chondroitin is synthesized as proteoglycans, sulfated and secreted to the cell surface or extracellular matrix.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
6.90e-158 1 298 70 350
4.03e-37 6 240 165 383
4.03e-37 6 240 165 383
5.13e-37 6 240 178 396
5.13e-37 6 240 178 396

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
1.00e-36 6 240 52 270
Crystal structure of human wild type beta-1,4-galactosyltransferase-1 (B4GalT1) in apo-closed dimeric form [Homo sapiens],6FWU_B Crystal structure of human wild type beta-1,4-galactosyltransferase-1 (B4GalT1) in apo-closed dimeric form [Homo sapiens]
1.10e-36 6 240 56 274
Crystal structure of human wild type beta-1,4-galactosyltransferase-1 (B4GalT1) in apo-open monomeric form [Homo sapiens]
3.76e-36 6 240 65 283
Crystal Structure of Lactose Synthase, Complex with Glucose [Bos taurus],1NF5_D Crystal Structure of Lactose Synthase, Complex with Glucose [Bos taurus],1NKH_B Crystal structure of Lactose synthase complex with UDP and Manganese [Bos taurus],1NKH_D Crystal structure of Lactose synthase complex with UDP and Manganese [Bos taurus],1NQI_B crystal structure of lactose synthase, a 1:1 complex between beta1,4-galactosyltransferase and alpha-lactalbumin in the presence of GlcNAc [Bos taurus],1NQI_D crystal structure of lactose synthase, a 1:1 complex between beta1,4-galactosyltransferase and alpha-lactalbumin in the presence of GlcNAc [Bos taurus],1NWG_B Beta-1,4-Galactosyltransferase Complex With Alpha- Lactalbumin And N-Butanoyl-Glucoamine [Bos taurus],1NWG_D Beta-1,4-Galactosyltransferase Complex With Alpha- Lactalbumin And N-Butanoyl-Glucoamine [Bos taurus],1O23_B Crystal Structure Of Lactose Synthase In The Presence Of Udp-glucose [Bos taurus],1O23_D Crystal Structure Of Lactose Synthase In The Presence Of Udp-glucose [Bos taurus],1OQM_B A 1:1 complex between alpha-lactalbumin and beta1,4-galactosyltransferase in the presence of UDP-N-acetyl-galactosamine [Bos taurus],1OQM_D A 1:1 complex between alpha-lactalbumin and beta1,4-galactosyltransferase in the presence of UDP-N-acetyl-galactosamine [Bos taurus]
3.76e-36 6 240 65 283
Chain B, BETA-1,4-GALACTOSYLTRANSFERASE [Bos taurus],1NMM_D Chain D, BETA-1,4-GALACTOSYLTRANSFERASE [Bos taurus],1O0R_A Chain A, beta-1,4-galactosyltransferase [Bos taurus],1O0R_B Chain B, beta-1,4-galactosyltransferase [Bos taurus]
3.85e-36 6 240 66 284
Human Lactose synthase: A 2:1 complex between human alpha-lactalbumin and human beta1,4-galactosyltransferase [Homo sapiens]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
9.12e-38 6 240 178 396
Beta-1,4-galactosyltransferase 1 OS=Mus musculus OX=10090 GN=B4galt1 PE=1 SV=1
6.82e-35 6 240 177 395
Beta-1,4-galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GALT1 PE=1 SV=5
1.96e-34 6 240 181 399
Beta-1,4-galactosyltransferase 1 OS=Bos taurus OX=9913 GN=B4GALT1 PE=1 SV=3
7.20e-33 6 226 123 328
Beta-1,4-galactosyltransferase 4 OS=Homo sapiens OX=9606 GN=B4GALT4 PE=1 SV=1
1.00e-32 6 237 123 338
Beta-1,4-galactosyltransferase 4 OS=Cricetulus griseus OX=10029 GN=B4GALT4 PE=2 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI CS Position
1.000050 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in PHPALM_18638-t46_1-p1.