CAZyme Information: PAAG_05245-t30_1-p1

Basic Information

• Species: Paracoccidioides lutzii
• Lineage: Ascomycota; Eurotiomycetes; ; NA; Paracoccidioides; Paracoccidioides lutzii
• CAZyme ID: PAAG_05245-t30_1-p1
• CAZy Family: GH55
• CAZyme Description: 1,3-beta-glucanosyltransferase gel2

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
471		51669.78	5.1974

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_PlutziiPb01	8953	502779	127	8826

• Gene Location: location=KN294004:882557-884407(+)

Full Sequence      

MTLLRYFTVLFALVASTVHAVTPISIEGSQFVNPVSKKRFQIIGVDYQPGGAAGYKEKGG
ADPLSDGDICLRDAALLQRLGVNTIRIYNLNPATNHDLCVSIFNAAGIYLILDVNSPIAH
QSLNRADPASTYHKGYMERVFGIVEAFKDYPNTLAFFGGNEVINEDAVKEVPAYIRAVQR
DIKEYISKHAPRSIPVGYSAADIRNILADTWAYMSCQIDDSDISLSDFFGLNSYSWCGDA
SFTTSGYNKLVEQFAETSLPVFFSEYGCNEVQPRIFTEVGALYGKEMTKAMGGGLVYEYS
QESNDFGLVQLHPNNTATILIDYDNLMDQYRKVDLSLLESLDPSATSIKPPKCSPDLIKD
TKHFENDFKVPKAPEEVPEMIKNGIKNPNKGNLVEVKNTKVKFEVYNKDGVILENLSIKV
LQDFQSNLPGEKTSGAPGAVKEKKKGAASTLSTSNALSLLAAVVGLTLLMV

Enzyme Prediction     

EC	2.4.1.-:8

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH72	19	333	1.9e-121	0.9903846153846154

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
397351	Glyco_hydro_72	1.06e-146	13	334	1	315	Glucanosyltransferase. This is a family of glycosylphosphatidylinositol-anchored beta(1-3)glucanosyltransferases. The active site residues in the Aspergillus fumigatus example are the two glutamate residues at 160 and 261.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
EEH34196.1|GH72	0.0	1	471	1	471
AAQ17182.1|GH72	5.43e-221	159	471	3	315
QSS52935.1|GH72	1.30e-208	1	471	1	472
QSS57965.1|GH72	1.50e-207	1	471	1	472
QSS76470.1|GH72	1.60e-206	1	471	58	529

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2W62_A	4.32e-71	24	334	36	344	Saccharomyces cerevisiae Gas2p in complex with laminaripentaose [Saccharomyces cerevisiae],2W63_A Saccharomyces Cerevisiae Gas2p In Complex With Laminaritriose And Laminaritetraose [Saccharomyces cerevisiae],5O9O_A Crystal structure of ScGas2 in complex with compound 7. [Saccharomyces cerevisiae S288C],5O9P_A Crystal structure of Gas2 in complex with compound 10 [Saccharomyces cerevisiae S288C],5O9Q_A Crystal structure of ScGas2 in complex with compound 6 [Saccharomyces cerevisiae S288C],5O9R_A Crystal structure of ScGas2 in complex with compound 9 [Saccharomyces cerevisiae S288C],5O9Y_A Crystal structure of ScGas2 in complex with compound 11 [Saccharomyces cerevisiae S288C],5OA2_A Crystal structure of ScGas2 in complex with compound 8 [Saccharomyces cerevisiae S288C],5OA2_B Crystal structure of ScGas2 in complex with compound 8 [Saccharomyces cerevisiae S288C],5OA2_C Crystal structure of ScGas2 in complex with compound 8 [Saccharomyces cerevisiae S288C],5OA6_A Crystal structure of ScGas2 in complex with compound 12 [Saccharomyces cerevisiae S288C]
2W61_A	1.19e-70	24	334	36	344	Saccharomyces cerevisiae Gas2p apostructure (E176Q mutant) [Saccharomyces cerevisiae]
5FIH_A	1.19e-70	24	334	36	344	SACCHAROMYCES CEREVISIAE GAS2P (E176Q MUTANT) IN COMPLEX WITH LAMINARITETRAOSE AND LAMINARIPENTAOSE [Saccharomyces cerevisiae]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P0C954|GEL2_ASPFU	3.33e-178	2	436	4	432	1,3-beta-glucanosyltransferase gel2 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=gel2 PE=3 SV=1
sp|B0Y8H9|GEL2_ASPFC	3.33e-178	2	436	4	432	1,3-beta-glucanosyltransferase gel2 OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) OX=451804 GN=gel2 PE=1 SV=1
sp|Q03655|GAS3_YEAST	1.05e-111	8	394	6	412	Probable 1,3-beta-glucanosyltransferase GAS3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=GAS3 PE=1 SV=1
sp|Q08271|GAS4_YEAST	3.40e-105	20	396	22	390	1,3-beta-glucanosyltransferase GAS4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=GAS4 PE=1 SV=1
sp|Q5AJY5|PGA4_CANAL	1.35e-89	16	332	14	320	1,3-beta-glucanosyltransferase PGA4 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=PGA4 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.000241	0.999731	CS pos: 20-21. Pr: 0.9790

TMHMM  Annotations     

There is no transmembrane helices in PAAG_05245-t30_1-p1.