CAZyme Information: P175DRAFT_0510530-t39_1-p1

Basic Information

• Species: Aspergillus ochraceoroseus
• Lineage: Ascomycota; Eurotiomycetes; ; Aspergillaceae; Aspergillus; Aspergillus ochraceoroseus
• CAZyme ID: P175DRAFT_0510530-t39_1-p1
• CAZy Family: GH74
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
982		108077.51	4.9320

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_AochraceoroseusIBT24754	9070	1392256	153	8917

• Gene Location: location=MSFN02000006:708531-711645(-)

Full Sequence      

MKASDLLCLLWLGWTIPFVSGIDNGKTTDVTWDKYSLSVKGERLFIYSGEFQYQRLPVPE
MWLDVFQKLRANGFNAVSVYFFWSWHSASEGEYDFTSGAHDIQRLFDYAKDAGLYVIARA
GPYCNAETSAGGYALWAANGQMGSERTSDEAYYRLWKPWVLEVGKIIAANQITNGGPVIL
NQHENEYQETSYNSGATQVVYMEQIAEAFEEAGILVPSTHNEKGMRSVSWSTDYHDVGGA
VNVYGLDSYPGGLSCTNPNTGFNLVRNYYQWFQNYSFTQPEFLPEFEGGWFQPWGGYVYD
TCQAELSPEFPDVYYKNNVGSRVTLQSIYMVFGGTNWGHSAAPVVYTSYDYSAPLRETRE
VRDKLKQTKLLGLFTRVSKDLLKTYMEGNGTGYTSDDSIFTWALRNPDTNAGFFVVAHES
SPSRAVTNFTLTVNTTAGELSIPDIQLAGRQSKIIVTDYTAGKQTSLLYSSAEVLTYATL
DVDVLVFYLNVGQKGVFAFRDAPAHVSFKEYGSSRLIASKTSYGTQYSYVQTEGVTVVKF
SNGVLAYLLDKASAWNFFAPPLTSNPDVAPGEQVLVQGPYLVRSASIHGDTIEVIGDNAN
TTSLEVYTGKSHVQKVKWNNKLVKTKKTAYGSLIGTAPGVENAKVSLPSLGPWKAQDTLP
EIDPDYDDTNWTQCNKSTTVNGQPPLSLPVLYSGDYGYHAGTKLYRGRFDGKNATGVNVT
VQNGIAAGWAAWLNGEYIGGALGDPGLASTQAVLSLNPSSLRSRDNVLMIVTDYTGHDED
NVKPHGAQNARGVLGATLVGGGDFTSWRIQGNAGGEKNIDPVRGPMNEGGLYGERMGWHL
PGYRAPTTASTSSPLDGVLGAEGRFYTTTFTLDLDSDLDVPIGLQLGAPEGTHAVVQIFM
NGYQYGHYLPHIGPQSLFPFPPGVINQQGENTLAISLWALTDQGARLDQVELTAYAKYRS
GFEFGRDWSYLQPRWEDRSMYA

Enzyme Prediction     

EC	-	-

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH35	38	371	6.9e-84	0.9837133550488599

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
396048	Glyco_hydro_35	2.69e-82	36	372	1	315	Glycosyl hydrolases family 35.
402180	BetaGal_dom2	9.46e-72	381	556	1	180	Beta-galactosidase, domain 2. This is the second domain of the five-domain beta-galactosidase enzyme that altogether catalyzes the hydrolysis of beta(1-3) and beta(1-4) galactosyl bonds in oligosaccharides as well as the inverse reaction of enzymatic condensation and trans-glycosylation. This domain is made up of 16 antiparallel beta-strands and an alpha-helix at its C-terminus. The fold of this domain appears to be unique. In addition, the last seven strands of the domain form a subdomain with an immunoglobulin-like (I-type Ig) fold in which the first strand is divided between the two beta-sheets. In penicillin spp this strand is interrupted by a 12-residue insertion which forms an additional edge-strand to the second beta-sheet of the sub-domain. The remainder of the second domain forms a series of beta-hairpins at its N-terminus, four strands of which are contiguous with part of the Ig-like sub-domain, forming in total a seven-stranded antiparallel beta-sheet. This domain is associated with family Glyco_hydro_35, pfam01301, which is N-terminal to it, but itself has no metazoan members.
198097	BetaGal_dom2	6.16e-57	380	557	1	182	Beta-galactosidase, domain 2. This is the second domain of the five-domain beta-galactosidase enzyme that altogether catalyses the hydrolysis of beta(1-3) and beta(1-4) galactosyl bonds in oligosaccharides as well as the inverse reaction of enzymatic condensation and trans-glycosylation. This domain is made up of 16 antiparallel beta-strands and an alpha-helix at its C terminus. The fold of this domain appears to be unique. In addition, the last seven strands of the domain form a subdomain with an immunoglobulin-like (I-type Ig) fold in which the first strand is divided between the two beta-sheets. In penicillin spp this strand is interrupted by a 12-residue insertion which forms an additional edge-strand to the second beta-sheet of the sub-domain. The remainder of the second domain forms a series of beta-hairpins at its N terminus, four strands of which are contiguous with part of the Ig-like sub-domain, forming in total a seven-stranded antiparallel beta-sheet. This domain is associated with family Glyco_hydro_35, which is N-terminal to it, but itself has no metazoan members.
166698	PLN03059	3.38e-34	1	370	2	344	beta-galactosidase; Provisional
404274	BetaGal_dom4_5	1.11e-33	832	943	1	111	Beta-galactosidase jelly roll domain. This domain is found in beta galactosidase enzymes. It has a jelly roll fold.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QMW27553.1|GH35	0.0	1	982	1	984
QRD81954.1|GH35	0.0	1	982	1	984
QMW39624.1|GH35	0.0	1	982	1	984
BAE57280.1|GH35	0.0	1	982	1	984
UDD55445.1|GH35	0.0	1	982	1	984

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
1TG7_A	4.39e-192	30	952	6	943	Native structure of beta-galactosidase from Penicillium sp. [Penicillium sp.],1XC6_A Native Structure Of Beta-Galactosidase from Penicillium sp. in complex with Galactose [Penicillium sp.]
5IFP_A	3.21e-178	30	953	46	980	Structure Of Beta-galactosidase From Aspergillus Niger [Aspergillus niger CBS 513.88]
5IFT_A	8.93e-178	30	953	46	980	STRUCTURE OF E298Q-BETA-GALACTOSIDASE FROM ASPERGILLUS NIGER IN COMPLEX WITH 3-b-Galactopyranosyl glucose [Aspergillus niger CBS 513.88],5IHR_A Structure Of E298q-beta-galactosidase From Aspergillus Niger In Complex With Allolactose [Aspergillus niger CBS 513.88],5JUV_A STRUCTURE OF E298Q-BETA-GALACTOSIDASE FROM ASPERGILLUS NIGER IN COMPLEX WITH 6-b-Galactopyranosyl galactose [Aspergillus niger CBS 513.88],5MGC_A STRUCTURE OF E298Q-BETA-GALACTOSIDASE FROM ASPERGILLUS NIGER IN COMPLEX WITH 4-Galactosyl-lactose [Aspergillus niger CBS 513.88],5MGD_A STRUCTURE OF E298Q-BETA-GALACTOSIDASE FROM ASPERGILLUS NIGER IN COMPLEX WITH 6-Galactosyl-lactose [Aspergillus niger CBS 513.88]
3OG2_A	1.86e-173	30	963	26	986	Chain A, Beta-galactosidase [Trichoderma reesei],3OGR_A Chain A, Beta-galactosidase [Trichoderma reesei],3OGS_A Chain A, Beta-galactosidase [Trichoderma reesei],3OGV_A Chain A, Beta-galactosidase [Trichoderma reesei]
4IUG_A	1.46e-168	30	978	46	1001	Crystal structure of beta-galactosidase from Aspergillus oryzae in complex with galactose [Aspergillus oryzae]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|B6QHA9|BGALC_TALMQ	0.0	24	982	24	999	Probable beta-galactosidase C OS=Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333) OX=441960 GN=lacC PE=3 SV=1
sp|B8N2I5|BGALC_ASPFN	0.0	1	982	1	984	Probable beta-galactosidase C OS=Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 / SRRC 167) OX=332952 GN=lacC PE=3 SV=1
sp|A7EZS5|BGALC_SCLS1	0.0	4	982	8	984	Probable beta-galactosidase C OS=Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) OX=665079 GN=lacC PE=3 SV=1
sp|Q2UMD5|BGALC_ASPOR	0.0	1	982	1	984	Probable beta-galactosidase C OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) OX=510516 GN=lacC PE=3 SV=1
sp|B0Y752|BGALC_ASPFC	0.0	1	982	1	983	Probable beta-galactosidase C OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) OX=451804 GN=lacC PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.000220	0.999761	CS pos: 21-22. Pr: 0.9756

TMHMM  Annotations     

There is no transmembrane helices in P175DRAFT_0510530-t39_1-p1.