logo
sublogo
You are browsing environment: FUNGIDB
help

CAZyme Information: P174DRAFT_442247-t37_1-p1

You are here: Home > Sequence: P174DRAFT_442247-t37_1-p1

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Aspergillus novofumigatus
Lineage Ascomycota; Eurotiomycetes; ; Aspergillaceae; Aspergillus; Aspergillus novofumigatus
CAZyme ID P174DRAFT_442247-t37_1-p1
CAZy Family GH3
CAZyme Description neuraminidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
419 MSZS01000005|CGC3 45947.56 9.9158
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_AnovofumigatusIBT16806 11729 1392255 197 11532
Gene Location

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.18:1 3.2.1.-:1

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH33 54 390 1.4e-58 0.9327485380116959

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
271229 Sialidase 7.29e-121 35 396 1 361
sialidases/neuraminidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed beta-propeller fold. This hierarchy includes eubacterial, eukaryotic, and viral sialidases.
271234 Sialidase_non-viral 1.21e-63 54 396 10 339
Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases.
404074 BNR_2 1.15e-12 117 370 27 279
BNR repeat-like domain. This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
1.35e-292 1 401 1 401
5.54e-219 21 401 21 404
1.11e-203 33 401 2 371
2.42e-200 21 402 34 420
9.50e-188 21 402 18 399

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
4.95e-293 1 401 17 417
Structural evaluation the Y358H mutant of the aspergillus fumigatus kdnase (sialidase) [Aspergillus fumigatus Af293],4M4N_B Structural evaluation the Y358H mutant of the aspergillus fumigatus kdnase (sialidase) [Aspergillus fumigatus Af293]
9.99e-293 1 401 17 417
Structural evaluation R171L mutant of the aspergillus fumigatus kdnase (sialidase) [Aspergillus fumigatus Af293],4M4V_B Structural evaluation R171L mutant of the aspergillus fumigatus kdnase (sialidase) [Aspergillus fumigatus Af293]
1.42e-292 1 401 17 417
Structural evaluation D84A mutant of the aspergillus fumigatus kdnase (sialidase) [Aspergillus fumigatus Af293],4M4U_B Structural evaluation D84A mutant of the aspergillus fumigatus kdnase (sialidase) [Aspergillus fumigatus Af293]
2.30e-280 21 401 1 381
The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural And Mechanistic Insights [Aspergillus fumigatus Af293],2XZI_B The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural And Mechanistic Insights [Aspergillus fumigatus Af293],2XZJ_A The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural And Mechanistic Insights [Aspergillus fumigatus Af293],2XZJ_B The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural And Mechanistic Insights [Aspergillus fumigatus Af293],2XZK_A The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural And Mechanistic Insights [Aspergillus fumigatus Af293],2XZK_B The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural And Mechanistic Insights [Aspergillus fumigatus Af293]
2.11e-276 21 401 1 381
Crystal structure of Aspergillus fumigatus sialidase [Aspergillus fumigatus],2XCY_B Crystal structure of Aspergillus fumigatus sialidase [Aspergillus fumigatus]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
2.40e-293 1 401 1 401
Exo-alpha-sialidase OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=AFUA_4G13800 PE=1 SV=2
8.15e-214 21 401 24 403
Exo-alpha-sialidase ARB_03431 OS=Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331 GN=ARB_03431 PE=1 SV=1
2.36e-18 54 400 63 401
Sialidase OS=Micromonospora viridifaciens OX=1881 GN=nedA PE=1 SV=1
2.72e-13 57 375 202 527
Sialidase OS=Bacteroides fragilis (strain YCH46) OX=295405 GN=nanH PE=3 SV=2
5.68e-09 37 273 329 633
Sialidase A OS=Streptococcus pneumoniae OX=1313 GN=nanA PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI CS Position
0.000239 0.999730 CS pos: 20-21. Pr: 0.9788

TMHMM  Annotations      help

There is no transmembrane helices in P174DRAFT_442247-t37_1-p1.