CAZyme Information: P168DRAFT_289795-t37_1-p1

Basic Information

• Species: Aspergillus campestris
• Lineage: Ascomycota; Eurotiomycetes; ; Aspergillaceae; Aspergillus; Aspergillus campestris
• CAZyme ID: P168DRAFT_289795-t37_1-p1
• CAZy Family: GH37
• CAZyme Description: sterol glucosyltransferase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
824		89430.29	7.8007

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_AcampestrisIBT28561	9929	1392248	173	9756

• Gene Location: location=MSFM01000005:1026709-1029419(-)

Full Sequence      

MSASKRSASVDLADPPHFTSTDSDAATVTDDGRVNVNLDSSAGKAALKRALSLLPATSEE
PPSPPPDYTQSTPFDIKLNIIIQVVGSRGDVQPFVALGNELQKHGHRVRIATHNTFDTFV
RGAGLEFYPIGGDPAELMAYMVKNPGLIPSVESLQEGDIKKKRVMVGEMLNGCWRSCIED
DLVSGMPFVADAIIANPPSFAHIHCAEALAIPLHLMFTMPWSPTTAYPHPLANLRYSGKN
QKFANSVSYGVVEWLTWQGLGDVINTWRSTIDLEPVPTNEGATMAQTLKIPFTYCWSPAL
LPKPIDWPAYIDVCGFFFRDPPSYSPTPELAAFLQNGPPPIYVGFGSIVLDDSVEMTAIL
EEAVKLTGVRAIISRGWSKLGGESSSNILYLGDCPHDWLFERVSCVIHHGGAGTTACGLR
YGKPTTIVPFFGDQPFWGKIVAASGAGPDPIPHRSLTAENLADAIRFCLNPSTLDAAENL
AIKMLEETGVAKAVECFHRNLPREKMRCAVLPDRPAAWVYKKNKGKPIYLSKMAAQVILD
YMRVDKEDLKRHEIKPIVLQHRRFDPISGTTSAAFETGAGLAKATTNMLWKPYQEIQRGR
TSSRQPSVTRSLSTPSLSQTEPENPVPEKSSTAPPRLSTSPTRIDWMTAATAAATSAKGV
GQFIGKYYKGMAVDIPLATTEGLRAIPRLYGEEVPEYVVRDWKSGAAAGGKNFIHGMRGG
LTDMLTQSYQGGKDKGPLGVGKGFLKGTVGLATKVPSAALGLVAYPGQGICKSLHNTIRF
QTRREITAARYREGVFLLRVEGGSLDQGDVVDLFEVLRNSAGDF

Enzyme Prediction     

EC	2.4.1.173:23	2.4.1.-:3

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT1	104	497	2.3e-57	0.9607329842931938

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
340817	GT1_Gtf-like	2.62e-81	78	499	1	403	UDP-glycosyltransferases and similar proteins. This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.
224732	YjiC	1.23e-45	80	495	4	393	UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism].
397255	Glyco_transf_28	5.60e-24	80	228	1	139	Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities.
273616	MGT	0.002	391	495	270	384	glycosyltransferase, MGT family. This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance]

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QMW26390.1|GT1	0.0	5	820	7	809
QMW38469.1|GT1	0.0	5	820	7	809
UCK58945.1|GT1	0.0	5	820	7	826
QRD87509.1|GT1	0.0	5	820	7	826
BAC56174.1|GT1	0.0	30	820	42	831

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5XVM_A	1.16e-76	66	501	8	439	Sterol 3-beta-glucosyltransferase (ugt51) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [Saccharomyces cerevisiae S288C],5XVM_B Sterol 3-beta-glucosyltransferase (ugt51) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [Saccharomyces cerevisiae S288C]
5GL5_A	1.97e-76	66	501	28	459	Sterol 3-beta-glucosyltransferase (ugt51) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c): UDPG complex [Saccharomyces cerevisiae S288C],5GL5_B Sterol 3-beta-glucosyltransferase (ugt51) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c): UDPG complex [Saccharomyces cerevisiae S288C]
1IIR_A	9.84e-31	78	511	1	408	Crystal Structure of UDP-glucosyltransferase GtfB [Amycolatopsis orientalis]
3H4I_A	4.65e-27	78	471	1	352	Chimeric Glycosyltransferase for the generation of novel natural products [Amycolatopsis orientalis],3H4T_A Chimeric Glycosyltransferase for the generation of novel natural products - GtfAH1 in complex with UDP-2F-Glc [Amycolatopsis orientalis]
1RRV_A	2.02e-24	78	505	1	403	X-ray crystal structure of TDP-vancosaminyltransferase GtfD as a complex with TDP and the natural substrate, desvancosaminyl vancomycin. [Amycolatopsis orientalis],1RRV_B X-ray crystal structure of TDP-vancosaminyltransferase GtfD as a complex with TDP and the natural substrate, desvancosaminyl vancomycin. [Amycolatopsis orientalis]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q9XIG1|U80B1_ARATH	3.32e-128	77	504	155	577	Sterol 3-beta-glucosyltransferase UGT80B1 OS=Arabidopsis thaliana OX=3702 GN=UGT80B1 PE=1 SV=1
sp|Q9M8Z7|U80A2_ARATH	1.36e-126	78	519	193	628	Sterol 3-beta-glucosyltransferase UGT80A2 OS=Arabidopsis thaliana OX=3702 GN=UGT80A2 PE=1 SV=1
sp|Q6C8M8|ATG26_YARLI	1.86e-75	77	501	994	1413	Sterol 3-beta-glucosyltransferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) OX=284591 GN=ATG26 PE=3 SV=3
sp|Q54IL5|UGT52_DICDI	2.37e-75	78	502	1164	1610	UDP-sugar-dependent glycosyltransferase 52 OS=Dictyostelium discoideum OX=44689 GN=ugt52 PE=2 SV=1
sp|P0CN90|ATG26_CRYNJ	7.79e-74	62	513	1014	1475	Sterol 3-beta-glucosyltransferase OS=Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) OX=214684 GN=ATG26 PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000061	0.000002

TMHMM  Annotations     

There is no transmembrane helices in P168DRAFT_289795-t37_1-p1.