CAZyme Information: OTA34680.1

Basic Information

• Species: Hortaea werneckii
• Lineage: Ascomycota; Dothideomycetes; ; Teratosphaeriaceae; Hortaea; Hortaea werneckii
• CAZyme ID: OTA34680.1
• CAZy Family: GH5
• CAZyme Description: unspecified product

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
548	MUNK01000055|CGC1	57585.63	5.3410

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_HwerneckiiEXF-2000	15649	1157616	29	15620

• Gene Location: location=MUNK01000055:118156-119863(+)

Full Sequence      

MKAFAVGATAFSLASTASAVATSSVPNTDINFQLSIPETTASSGNGDIYFQISAPTTYSW
VALGQGNGMSGSNMFVVYTSADGDNVTVSPRLGTGHVMPEYNSNADISVLEGSGVSNGVM
TANVRCGSCSSWDGGSMDFSSSSSNWIYGYRSGSPIESDSVEESISQHNDANGFTWDLSV
ARTTDVDTSDLFASGSGSGESTTATATGSSPTTSISCTPISSTSGCPTAWPTERPNGRPN
WPSSCFDDGPPAWATDAPWNDGDGDGPWNGGHGPWDHSDKLRKRQSDNDCPAGYEPADGS
GSSGSSSGSGSSASFGNNANAFRSMSPEQREKMVTAHGALAALAFVALFPIGGILVRLAS
FTGLVWVHAAFQLVAYAIYIAAFGIGVWLASNVRLLSNAHPVIGIILFIILFAQPILGLI
HHRVFKKTGYRTWSSYLHLTIGRVAILLGIINGGLGLRLANAEQAPIIAYAVIAAVIGAT
YIAAVVFGELKRKRRLQNQPPTYHRSQKDLGHEMQSHSDSSSEDQQPMEWYGPSDESSNG
RAPPHYGS

Enzyme Prediction     

No EC number prediction in OTA34680.1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
AA8	26	185	9e-22	0.8956043956043956

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
187688	CDH_like_cytochrome	7.46e-55	10	178	1	168	Heme-binding cytochrome domain of fungal cellobiose dehydrogenases. Cellobiose dehydrogenase (CellobioseDH or CDH) is an extracellular fungal oxidoreductase that degrades both lignin and cellulose. Specifically, CDHs oxidize cellobiose, cellodextrins, and lactose to corresponding lactones, utilizing a variety of electron acceptors. Class-II CDHs are monomeric hemoflavoenzymes that are comprised of a b-type cytochrome domain linked to a large flavodehydrogenase domain. The cytochrome domain of CDH and related enzymes, which this model describes, folds as a beta sandwich and complexes a heme molecule. It is found at the N-terminus of this family of enzymes, and belongs to the DOMON domain superfamily, a ligand-interacting motif found in all three kingdoms of life.
406418	CDH-cyt	1.44e-32	21	185	11	177	Cytochrome domain of cellobiose dehydrogenase. CDH-cyt is the cytochrome domain, at the N-terminus, of cellobiose dehydrogenase. CDH-cyt folds as a beta sandwich with the topology of the antibody Fab V(H) domain and binds iron. The haem iron is ligated by Met83 and His181 in UniProtKB:Q01738.
176490	Cyt_b561_FRRS1_like	1.41e-25	313	486	15	191	Eukaryotic cytochrome b(561), including the FRRS1 gene product. Cytochrome b(561), as found in eukaryotes, similar to and including the human FRRS1 gene product (ferric-chelate reductase 1), also called SDR-2 (stromal cell-derived receptor 2). This family comprises a variety of domain architectures, many of which contain dopamine beta-monooxygenase (DOMON) domains. The protein might act as a ferric-chelate reductase, catalyzing the reduction of Fe(3+) to Fe(2+), such as associated with the transport of iron from the endosome to the cytoplasm. It is assumed that this protein uses ascorbate as the electron donor. Belongs to the cytochrome b(561) family, which are secretory vesicle-specific electron transport proteins. Cytochromes b(561) are integral membrane proteins that bind two heme groups non-covalently, and may have six alpha-helical trans-membrane segments.
187689	DOMON_DOH	2.31e-07	43	125	16	96	DOMON-like domain of copper-dependent monooxygenases and related proteins. This diverse family characterizes DOMON domains found in dopamine beta-hydroxylase (DBH), monooxygenase X (MOX), and various other proteins, some of which contain DOMON domains exclusively; the family is not restricted to eukaryotes. DBH is a membrane-bound enzyme that converts dopamine to L-norepinephrine, and plays a central role in the metabolism of catecholamine neurotransmitters. DOMON domains were initially thought to confer protein-protein interactions. They were subsequently found as a heme-binding motif in cellobiose dehydrogenase, an extracellular fungal oxidoreductase that degrades both lignin and cellulose, and in ethylbenzene dehydrogenase, an enzyme that aids in the anaerobic degradation of hydrocarbons. The domain interacts with sugars in the type 9 carbohydrate binding modules (CBM9), which are present in a variety of glycosyl hydrolases, and it can also be found at the N-terminus of sensor histidine kinases.
227493	SPT5	2.98e-04	71	274	430	607	Transcription elongation factor [Transcription].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
SMR44317.1|AA0	1.30e-94	12	500	15	393
SMR42136.1|AA0	1.30e-94	12	500	15	393
CAE7013938.1|AA8	2.22e-85	17	494	18	386
SMR57731.1|AA0	3.21e-77	32	492	27	365
SMR55355.1|AA0	3.21e-77	32	492	27	365

PDB Hits     

OTA34680.1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q9M363|B561I_ARATH	6.39e-07	335	461	218	344	Cytochrome b561 and DOMON domain-containing protein At3g61750 OS=Arabidopsis thaliana OX=3702 GN=At3g61750 PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.000315	0.999665	CS pos: 19-20. Pr: 0.9819

TMHMM  Annotations     

Start	End
334	356
363	385
400	422
435	457
467	489