CAZyme Information: OTA23428.1

Basic Information

• Species: Hortaea werneckii
• Lineage: Ascomycota; Dothideomycetes; ; Teratosphaeriaceae; Hortaea; Hortaea werneckii
• CAZyme ID: OTA23428.1
• CAZy Family: AA7
• CAZyme Description: Helicase ATP-binding domain-containing protein [Source:UniProtKB/TrEMBL;Acc:A0A1Z5SRS6]

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
2303		257638.75	5.4939

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_HwerneckiiEXF-2000	15649	1157616	29	15620

• Gene Location: location=MUNK01000297:29450-37096(-)

Full Sequence      

MARKDFHHPFQPYDIQQQFMEAMYECMEDKKVGIFESPTGTGKSLSLICSSLTWLREHKR
KAFDEAVAAIEVDDDEPEWMANAARDARKQEIRQMRNDFEKRLQAVREHEQKIREKAAKN
EPLAKRRKVAVDEPEGLLGDDDQFLLDDYDSDEERAKDSKSNVLGYSAETTKLMEQLGML
QKRNNEQVQEETFEELKIFFCSRTHSQLSQFVGELQRVKLPAALPSDTSNPDGPDNAVEH
LKQLSLGSRKNLCINPRVSTLNSQTAINERCIELQQGSTPKEQKCPFLPEKEKEDVLIDF
RDHALARVRDIEDLANIGSKLGVCPYYASRPAIKPAEMVTLPYPLLLQKTARDALDISVK
DQVVIIDEAHNLMDAIESIHSGQISEAQLKLARESLMTYLQKFRNRLKGSNRVYVTQVVR
VIDSILSFTSSLSAETSRDGTLGPGQLLSGKGVDQINLAKLVRYISDSKLARKVQGYIAS
VARDERNTSEKQKAAASTPDVPTLTHVQNFLMTLMNPSKEGRFFWSKEGGTAFIRYMLLD
PSEHFREIVEDARAVILAGGTMSPMDDYRKHLFPNLLVRAVTADVEGPLEFSYKSRNTTS
MERIGKALLALAPHVKGGLVVFFPSYGFLEAVLACWKQHSMIAKLEGIMPVFSDDRGGSA
DATFKDYSEAATRGKGAILLSVIGGKLSEGINFSDDLGRCVVVVGLPFPNLQTAEWQAKM
QYIEEKSTAKGEPKGKASREHAENVCMRSVNQAIGRVIRHQNDWASVVLMDSRYSQPRIR
SKLPGETAAEENATSYFPLLDRIADGHFDSATTDQELYTRFRSTLREDGHLSQSEQLSSF
DLALSLHAAAPRIEAQYQYYNTSVRPTLASEGDDECESWVHVPFNGQKYCQPDMTEASAQ
KVDSVTGHVHELPFDRVLGDQDNVTPSVLYADITSDSFKKFHKTISKTAREGRTSYRVRY
VPPKAATSMPLTVSGYGVELALKRTDYIVIDDRQAEEEQKDGTVPATEATLTEEEVADLR
PLSSSELLRLGLKAASFVLSSDTPFDTLLRLSQDFPKHSGSIAATNVSKDFLQEHRENRE
TLLPPGFNVLWINGVQIMGRDVDAYSLLEHLRRERKMIGGVRELGLSGPEAIDLLSHEAI
TASSADQEVQRYDWRDENEGGDVIMWLNDIEKDKRYAEWPGTVNALLVRTYPGQLPSCRR
NIHHVVLPVDFSDYKDVAVVVEQVQNFVRRKIPIRFGLVPLFHTQEGEQQAKLVYYLLDR
YGLTVALDYLGKSIIGSGRKYGAPQEKFFEAAIADRTLRSKKEQLPFNDVVTSGEFDGRL
KGAESYMSRLGAGSTKPPILLNGAPIEHTDDWLQVMSQRITIDLRIVQQAIFEETMGEDD
YLPEIFLARAVLRRNPIIVPEDDKDIRHLDLGELPFASLRSLPADSETIERELVHLTVAA
DFNQPEGFEQLIEALLFKQQHDNVELAVLPTGGSGKVTARLGLDQDGQVATDKLTSLLAV
YDMLSSNAKANGADGAESEASKQDTQLDLAARRSVYRQMLNAANEDTTAGGGQRAASLSS
AYKTIVAAAGLEANQEALILNGRLVGPFSSNASVEIEDLEALLEYERKKRLLPTALAIDD
LQIRDKASSPLAFARISNLIALSQVSDVPEGFFEAAPTLRTDVFKKFNSSHTAIKTGDMS
SASVQIVSAIDPASELAQRWVPIIKALSELDGVATTLFLNPKDRLEELPVKRFYRYVLDS
KPTFSADGSLESSIARFSGLPAEALLNIGMDLPPSWLVAPKESIHDLDNIKLSAVKPGSD
IEAVYELQHVLIEGHSRDTTLGIPPRGTQLVLGTDADSHFADTIVMANLGYFQFKANPGI
YRLALQKGRSEEIFQIDSAGTNGYKPRPGDNITEMALMSFRGATLYPRLSRKPGMEEEDV
LEAVKSTLDHFADGADQLLAQVGINGLKASKYMSKAAKLGSALFAGNDGKQSGGGIEPHA
DINIFSVASGHLFERMLNIMMVSVMKHTQHTVKFWFIEQFLSPSFKDFLPILAKEYGFKY
EMVTYKWPHWLRGQKEKQREIWGYKILYLDVLFPLDLDKVIFVDADQIVRTDMYELVRHD
LKGAPYGFTPMCDSRTEMEGFRFWKQGYWKNFLRGLPYHISALYVVDLKRFRQIAAGDRL
RQQYHQLSADPASLSNLDQDLPNHMQVALPIHSLPQDWLWCETWCSDEALKNAKTIDLCN
NPQTKEPKLDRARRQVPEWTLYDDEIAALAKKHKDSEVAGKPVAGNAADAGVQGQEEESV
QERLQREDAERERKKQAHVKDEL

Enzyme Prediction     

EC	2.4.1.-:29

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT24	1982	2229	4.7e-132	0.9959677419354839

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
408203	Glyco_transf_24	0.0	1982	2249	1	268	Glucosyltransferase 24. This is the catalytic domain found in UDP-glucose:glycoprotein glucosyltransferase (UGGT). This domain belongs to glucosyltransferase 24 family (GT24) A-type domain. The GT domain displays the expected glycosyltransferase type A (GT-A) fold.
133054	GT8_HUGT1_C_like	2.77e-178	1982	2229	1	248	The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family. C-terminal domain of glycoprotein glucosyltransferase (UGT). UGT is a large glycoprotein whose C-terminus contains the catalytic activity. This catalytic C-terminal domain is highly homologous to Glycosyltransferase Family 8 (GT 8) and contains the DXD motif that coordinates donor sugar binding, characteristic for Family 8 glycosyltransferases. GT 8 proteins are retaining enzymes based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. The non-catalytic N-terminal portion of the human UTG1 (HUGT1) has been shown to monitor the protein folding status and activate its glucosyltransferase activity.
273169	rad3	3.10e-149	189	784	54	685	DNA repair helicase (rad3). All proteins in this family for which funcitons are known are DNA-DNA helicases that funciton in the initiation of transcription and nucleotide excision repair as part of the TFIIH complex. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
408201	Thioredoxin_14	2.20e-98	1152	1398	1	248	Thioredoxin-like domain. This is the third out of four TRXL(thioredoxin-like) domains found in UDP-glucose:glycoprotein glucosyltransferase (UGGT).
224120	DinG	9.92e-72	1	784	5	628	Rad3-related DNA helicase [Replication, recombination and repair].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
UJO21924.1|GT24	0.0	786	2303	41	1547
SMR54488.1|GT24	0.0	786	2295	44	1535
SMQ51945.1|GT24	0.0	786	2295	44	1535
SMY25588.1|GT24	0.0	786	2295	44	1535
SMR56403.1|GT24	0.0	786	2295	44	1535

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5NV4_A	0.0	786	2255	30	1453	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
6TRT_A	0.0	786	2255	30	1453	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
5Y7O_A	0.0	786	1922	25	1124	Crystal structure of folding sensor region of UGGT from Thermomyces dupontii [Thermomyces dupontii],5Y7O_B Crystal structure of folding sensor region of UGGT from Thermomyces dupontii [Thermomyces dupontii]
5MU1_A	0.0	786	2255	30	1453	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],5MZO_A Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],5N2J_A Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],5N2J_B Chain B, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TRF_A Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
6TS2_A	0.0	786	2255	30	1219	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS2_B Chain B, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS2_C Chain C, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS2_D Chain D, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q09140|UGGG_SCHPO	3.68e-263	781	2261	36	1439	UDP-glucose:glycoprotein glucosyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=gpt1 PE=1 SV=2
sp|A1D8E4|CHL1_NEOFI	6.31e-232	4	784	6	828	ATP-dependent DNA helicase chl1 OS=Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) OX=331117 GN=chl1 PE=3 SV=1
sp|A2QY22|CHL1_ASPNC	1.02e-228	1	784	3	842	ATP-dependent DNA helicase chl1 OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) OX=425011 GN=chl1 PE=3 SV=1
sp|Q1E5T3|CHL1_COCIM	1.34e-226	2	784	4	826	ATP-dependent DNA helicase CHL1 OS=Coccidioides immitis (strain RS) OX=246410 GN=CHL1 PE=3 SV=1
sp|Q09332|UGGG_DROME	7.16e-224	769	2257	33	1515	UDP-glucose:glycoprotein glucosyltransferase OS=Drosophila melanogaster OX=7227 GN=Uggt PE=1 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000101	0.000000

TMHMM  Annotations     

There is no transmembrane helices in OTA23428.1.