CAZyme Information: OON11191.1

Basic Information

• Species: Batrachochytrium salamandrivorans
• Lineage: Chytridiomycota; Chytridiomycetes; ; NA; Batrachochytrium; Batrachochytrium salamandrivorans
• CAZyme ID: OON11191.1
• CAZy Family: GT92
• CAZyme Description: Chitobiosyldiphosphodolichol beta-mannosyltransferase [Source:UniProtKB/TrEMBL;Acc:A0A1S8W9Q1]

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
467	LYON01000011|CGC1	53077.65	7.0081

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_BsalamandrivoransBS	10186	N/A	51	10135

• Gene Location: location=LYON01000011:48132-49938(+)

Full Sequence      

MFQELLVVVISIPIVALAALWMSPLEKRRVVVLVLGDLGHSPRMQNHALSLAQSGFTVDF
IGYNESPLRSELMQHSAINVRFLPTPQRIRTDYKMVFIFMGIWRSVSQMISLLWILLWTV
PKPEYILVQNPPAIPTLVATKFITFILGVRLIVDWHNFGFSLMSEKFSKNKILFNILKRY
EQWGGSSAYLHLCVTEAMAQELKNGWKLCGDVVVVYDRPASHFQVITTQERHNLFSKLDF
TDQAVCYFDSTSTATETLITEQTLDSNIVLKPDRPAILVSSTSWTPDEDFGILLSALELY
DKEAKHRSEKLNSASPLSKLVMIITGKGPMRLEFERAVSNLNMAYVSIKFAWLTPQDYPT
LVASADLGISLHTSSSGMDLPMKIVDMFGCGVPVCTYYYPTVEELVQDKRNGVYFRDSAE
LSQRLIEIIGNFPNPNQTRAALVTGVKEYRSKSWDMYWREVVLPHIE

Enzyme Prediction     

EC	2.4.1.142:10	2.4.1.-:1

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT33	27	464	1.6e-152	0.9952941176470588

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
340843	GT33_ALG1-like	1.05e-166	27	464	3	409	chitobiosyldiphosphodolichol beta-mannosyltransferase and similar proteins. This family is most closely related to the GT33 family of glycosyltransferases. The yeast gene ALG1 has been shown to function as a mannosyltransferase that catalyzes the formation of dolichol pyrophosphate (Dol-PP)-GlcNAc2Man from GDP-Man and Dol-PP-Glc-NAc2, and participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. In humans ALG1 has been associated with the congenital disorders of glycosylation (CDG) designated as subtype CDG-Ik.
215155	PLN02275	3.83e-142	27	428	4	370	transferase, transferring glycosyl groups
340825	GT4_WbuB-like	1.04e-11	36	431	12	362	Escherichia coli WbuB and similar proteins. This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.
340831	GT4_PimA-like	2.20e-10	39	431	15	333	phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.
223515	RfaB	1.45e-07	113	461	74	370	Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CAG7866879.1|GT33	3.73e-108	26	466	4	456
VDC63845.1|GT33	3.73e-108	26	466	4	456
CED84249.1|GT33	6.11e-107	3	464	12	510
VDD58754.1|GT33	1.48e-106	26	466	4	456
CAG7869101.1|GT33	6.99e-106	26	466	3	455

PDB Hits     

OON11191.1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q8L7M0|TUN_ARATH	1.76e-105	26	466	3	455	UDP-glycosyltransferase TURAN OS=Arabidopsis thaliana OX=3702 GN=TUN PE=2 SV=1
sp|Q5R7A2|ALG1_PONAB	2.70e-101	21	464	26	459	Chitobiosyldiphosphodolichol beta-mannosyltransferase OS=Pongo abelii OX=9601 GN=ALG1 PE=2 SV=1
sp|Q9BT22|ALG1_HUMAN	1.51e-100	21	464	26	459	Chitobiosyldiphosphodolichol beta-mannosyltransferase OS=Homo sapiens OX=9606 GN=ALG1 PE=1 SV=2
sp|Q921Q3|ALG1_MOUSE	5.13e-100	28	464	33	459	Chitobiosyldiphosphodolichol beta-mannosyltransferase OS=Mus musculus OX=10090 GN=Alg1 PE=1 SV=3
sp|O13933|ALG1_SCHPO	3.38e-88	26	467	23	421	Chitobiosyldiphosphodolichol beta-mannosyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=alg1 PE=3 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
0.996061	0.003984

TMHMM  Annotations     

Start	End
5	22
96	118
133	153