CAZyme Information: OEJ89444.1

Basic Information

• Species: Hanseniaspora uvarum
• Lineage: Ascomycota; Saccharomycetes; ; Saccharomycodaceae; Hanseniaspora; Hanseniaspora uvarum
• CAZyme ID: OEJ89444.1
• CAZy Family: GT32
• CAZyme Description: Chitin synthase 1

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1661		191774.38	5.1921

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_HuvarumAWRI3580	4061	N/A	0	4061

• Gene Location: location=LPNN01000004:448983-454987(-)

Full Sequence      

MARKPAFAKKTKKSTNSNNGNSAPHFSKFEDYFDYGVKRETDGERFAQSDTKKSTNAFND
ALNCYKTAIKIYNENPGFYSGDISVYQNIVYNYLRVKYDLLSEFKYVAGDVDITKFIPES
DINKELKESLFQDNKPTLDELRNEYESYSQTLQTDINTWDFFFNYLAYLSSYLEWIFELE
NXNIKDAMIIVQRQIEIFDKLKESSQIVFNDTYTNHQNFDDPVLAQNMALQKDTMFLPNQ
YNQNVVNTMSKLDINSLLEMETLVLKSIASIVEITYTTIXIKNETIDVYYEVLKTLETYS
QHIIQNSLVSSTVLSNVEIQEEINKDIYKETEETIYFTNTLMGFSXPENIKQYVIEVAND
LDNINVESKPVVVELLKSVLEILSPIKIIRESIKNNHKNETKVITSALGBLEMFYQILNM
VVKLDRQVIMSXNEKIKLGKVSTNNXGSEYCNLAELFLEVADIELQRSYWKQIESKSEES
AASFDLRKSYLKNAYSFVVNDLGSKETKKDSFVNDDARPEVRKPSAYHDEEIFHSDSESH
LDFYDNPNERDFDQPPMHKTFSDPFKSELNTNYSNTNSDHQSQQKSAYNVVNNQXEPEYF
HQNTENNEYIHQNQVVPNIEVANQYQQNERQHPYPNQMDFGQTHVPSSPFEDLEMGKMHT
YDDNESIILDLQGDEYPINSFLRKNGTMSNPYRDNKFYHDVWIRNEGPHMASDPFQQVAD
QHIQMDYNKELDPIDEYFDDDEEKHGDLSSMDKEVQFTSSFEDLAEKATDLKDEDNQEQK
TVPRRFILENGNFVFDCPIGSSLLNQYYKSFDNSQNMSNEFKFMRYQAVTCQPHEFSYKN
FVLRQQKFMIPRVTELMIVITMYNEDDFLLGRTLKGVFENIRHMLKKTRSKTWGPDAWKK
IVVTVVSDGRSKINPRAQALMSALGCYQDGFAKSEINGEEVLAHLYEHTSKVNISGINDD
GTVDLKCDQTSIPVQFLFCLKEQNQKKINSHRWAIEAFAESLNPNVICLLDAGTMPGKTS
IYNLWREFKNPRVGGACGEIKVDIGNFGKHLLNPLVASQNFEYKMSNILDKTTESCFGYI
SVLPGAFSAYRYQALLGKPLRKYFHGEDENIQMFESNMYLAEDRVLCYEIVTKDDFNWIL
KYCKDSFASTDVPDKIPEFILQRRRWMNGSFFAALYSFIHFPKIWSSGHSIVRKLFLTIE
ILYMMFQTLVSWFSLSSFFLVFRILTLSLSVTFPDVAAFNYLAVVFLWIYGFTVLATFIL
SLGNRPQGTHRFYLIVFVFFAILMIYTIFAAVYLSVHTVKDLVDEQTKVTFKTLLLKSQF
RDLLISMGSTYVLYIFSSIIYLQPWHMLTSFVQYLLISPSYINVLNIYAFANLHDVTWGT
KGAVKGKFLGSVQAKKDGTVQTEIPIHAAEIDANYRKYAYMISTKQQEETTQEKNMDEAK
QSYYATVRSIVLILWATTNFAVVSVILNVGGYAEYNAIKKGHSNDYSQTVQVVGPRARVY
FAIILWVVAFLAAIRAMGFEQKLISEISKGYFLLVGISVNDTEVELERVAKKVCGLRLFE
LDENDVHTNLWKKSIKDVKGQILSVSQFTLYAKTKKGTKPDFHRSQKSELANPLYEKFLK
LLRKELGSDELVQDGKFGGMMSCSLTNEGPCTIILDTDEAA

Enzyme Prediction     

EC	2.4.1.16:26	2.4.1.16:26

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	862	1028	5.6e-67	0.9938650306748467

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
396286	Chitin_synth_1	2.50e-88	862	1028	1	163	Chitin synthase. This region is found commonly in chitin synthases classes I, II and III. Chitin a linear homopolymer of GlcNAc residues, it is an important component of the cell wall of fungi and is synthesized on the cytoplasmic surface of the cell membrane by membrane bound chitin synthases.
133033	Chitin_synth_C	2.71e-77	858	1173	1	244	C-terminal domain of Chitin Synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin. Chitin synthase, also called UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyltransferase, catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of GlcNAc residues formed by covalent beta-1,4 linkages. Chitin is an important component of the cell wall of fungi and bacteria and it is synthesized on the cytoplasmic surface of the cell membrane by membrane bound chitin synthases. Studies with fungi have revealed that most of them contain more than one chitin synthase gene. At least five subclasses of chitin synthases have been identified.
396918	Tyr_Deacylase	9.47e-57	1520	1656	14	143	D-Tyr-tRNA(Tyr) deacylase. This family comprises of several D-Tyr-tRNA(Tyr) deacylase proteins. Cell growth inhibition by several d-amino acids can be explained by an in vivo production of d-aminoacyl-tRNA molecules. Escherichia coli and yeast cells express an enzyme, d-Tyr-tRNA(Tyr) deacylase, capable of recycling such d-aminoacyl-tRNA molecules into free tRNA and d-amino acid. Accordingly, upon inactivation of the genes of the above deacylases, the toxicity of d-amino acids increases. Orthologues of the deacylase are found in many cells.
238316	Dtyr_deacylase	3.49e-50	1522	1657	18	145	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not in archea; beta barrel-like fold structure; forms homodimers in which two surface cavities serve as the active site for tRNA binding
224407	Dtd	4.74e-50	1520	1657	16	145	D-Tyr-tRNAtyr deacylase [Translation, ribosomal structure and biogenesis].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CAR21671.1|GT2	0.0	659	1518	181	1037
CAG98729.1|GT2	0.0	611	1518	121	993
QEU58306.1|GT2	0.0	662	1518	158	993
CCD25666.1|GT2	5.02e-318	635	1518	247	1123
AJT18089.1|GT2	1.01e-317	661	1518	234	1115

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2OKV_A	2.23e-25	1517	1657	15	147	c-Myc DNA Unwinding Element Binding Protein [Homo sapiens],2OKV_B c-Myc DNA Unwinding Element Binding Protein [Homo sapiens],2OKV_C c-Myc DNA Unwinding Element Binding Protein [Homo sapiens],2OKV_D c-Myc DNA Unwinding Element Binding Protein [Homo sapiens]
2DBO_A	2.00e-23	1520	1659	16	147	Crystal structure of D-Tyr-tRNA(Tyr) deacylase from Aquifex aeolicus [Aquifex aeolicus VF5]
3KNF_A	2.31e-23	1520	1659	26	159	Crystal structure of D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum [Plasmodium falciparum 3D7],3KNF_B Crystal structure of D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum [Plasmodium falciparum 3D7],3KNF_C Crystal structure of D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum [Plasmodium falciparum 3D7],3KNF_D Crystal structure of D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum [Plasmodium falciparum 3D7],3KNF_E Crystal structure of D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum [Plasmodium falciparum 3D7],3KNF_F Crystal structure of D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum [Plasmodium falciparum 3D7],3KNP_A Crystal structure of DTD from Plasmodium falciparum [Plasmodium falciparum 3D7],3KNP_B Crystal structure of DTD from Plasmodium falciparum [Plasmodium falciparum 3D7],3KNP_C Crystal structure of DTD from Plasmodium falciparum [Plasmodium falciparum 3D7],3KNP_D Crystal structure of DTD from Plasmodium falciparum [Plasmodium falciparum 3D7],3KNP_E Crystal structure of DTD from Plasmodium falciparum [Plasmodium falciparum 3D7],3KNP_F Crystal structure of DTD from Plasmodium falciparum [Plasmodium falciparum 3D7],3KO3_A D-tyrosyl-tRNA(Tyr) deacylase from Plasmodium falciparum incomplex with ADP, obtained through soaking native enzyme crystal with the ATP [Plasmodium falciparum 3D7],3KO3_B D-tyrosyl-tRNA(Tyr) deacylase from Plasmodium falciparum incomplex with ADP, obtained through soaking native enzyme crystal with the ATP [Plasmodium falciparum 3D7],3KO3_C D-tyrosyl-tRNA(Tyr) deacylase from Plasmodium falciparum incomplex with ADP, obtained through soaking native enzyme crystal with the ATP [Plasmodium falciparum 3D7],3KO3_D D-tyrosyl-tRNA(Tyr) deacylase from Plasmodium falciparum incomplex with ADP, obtained through soaking native enzyme crystal with the ATP [Plasmodium falciparum 3D7],3KO3_E D-tyrosyl-tRNA(Tyr) deacylase from Plasmodium falciparum incomplex with ADP, obtained through soaking native enzyme crystal with the ATP [Plasmodium falciparum 3D7],3KO3_F D-tyrosyl-tRNA(Tyr) deacylase from Plasmodium falciparum incomplex with ADP, obtained through soaking native enzyme crystal with the ATP [Plasmodium falciparum 3D7],3KO4_A Crystal structure of D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum in complex with ADP [Plasmodium falciparum 3D7],3KO4_B Crystal structure of D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum in complex with ADP [Plasmodium falciparum 3D7],3KO4_C Crystal structure of D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum in complex with ADP [Plasmodium falciparum 3D7],3KO4_D Crystal structure of D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum in complex with ADP [Plasmodium falciparum 3D7],3KO4_E Crystal structure of D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum in complex with ADP [Plasmodium falciparum 3D7],3KO4_F Crystal structure of D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum in complex with ADP [Plasmodium falciparum 3D7],3KO5_A D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum in complex with ADP [Plasmodium falciparum 3D7],3KO5_B D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum in complex with ADP [Plasmodium falciparum 3D7],3KO5_C D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum in complex with ADP [Plasmodium falciparum 3D7],3KO5_D D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum in complex with ADP [Plasmodium falciparum 3D7],3KO5_E D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum in complex with ADP [Plasmodium falciparum 3D7],3KO5_F D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum in complex with ADP [Plasmodium falciparum 3D7],3KO7_A DTD from Plasmodium falciparum in complex with D-Lysine [Plasmodium falciparum 3D7],3KO7_B DTD from Plasmodium falciparum in complex with D-Lysine [Plasmodium falciparum 3D7],3KO7_C DTD from Plasmodium falciparum in complex with D-Lysine [Plasmodium falciparum 3D7],3KO7_D DTD from Plasmodium falciparum in complex with D-Lysine [Plasmodium falciparum 3D7],3KO7_E DTD from Plasmodium falciparum in complex with D-Lysine [Plasmodium falciparum 3D7],3KO7_F DTD from Plasmodium falciparum in complex with D-Lysine [Plasmodium falciparum 3D7],3KO9_A DTD from Plasmodium falciparum in complex with D-Arginine [Plasmodium falciparum 3D7],3KO9_B DTD from Plasmodium falciparum in complex with D-Arginine [Plasmodium falciparum 3D7],3KO9_C DTD from Plasmodium falciparum in complex with D-Arginine [Plasmodium falciparum 3D7],3KO9_D DTD from Plasmodium falciparum in complex with D-Arginine [Plasmodium falciparum 3D7],3KO9_E DTD from Plasmodium falciparum in complex with D-Arginine [Plasmodium falciparum 3D7],3KO9_F DTD from Plasmodium falciparum in complex with D-Arginine [Plasmodium falciparum 3D7],3KOB_A DTD from Plasmodium falciparum in complex with D-Glutamic acid [Plasmodium falciparum 3D7],3KOB_B DTD from Plasmodium falciparum in complex with D-Glutamic acid [Plasmodium falciparum 3D7],3KOB_C DTD from Plasmodium falciparum in complex with D-Glutamic acid [Plasmodium falciparum 3D7],3KOB_D DTD from Plasmodium falciparum in complex with D-Glutamic acid [Plasmodium falciparum 3D7],3KOB_E DTD from Plasmodium falciparum in complex with D-Glutamic acid [Plasmodium falciparum 3D7],3KOB_F DTD from Plasmodium falciparum in complex with D-Glutamic acid [Plasmodium falciparum 3D7],3KOC_A DTD from Plasmodium falciparum in complex with D-Histidine [Plasmodium falciparum 3D7],3KOC_B DTD from Plasmodium falciparum in complex with D-Histidine [Plasmodium falciparum 3D7],3KOC_C DTD from Plasmodium falciparum in complex with D-Histidine [Plasmodium falciparum 3D7],3KOC_D DTD from Plasmodium falciparum in complex with D-Histidine [Plasmodium falciparum 3D7],3KOC_E DTD from Plasmodium falciparum in complex with D-Histidine [Plasmodium falciparum 3D7],3KOC_F DTD from Plasmodium falciparum in complex with D-Histidine [Plasmodium falciparum 3D7],3KOD_A DTD from Plasmodium falciparum in complex with D-Serine [Plasmodium falciparum 3D7],3KOD_B DTD from Plasmodium falciparum in complex with D-Serine [Plasmodium falciparum 3D7],3KOD_C DTD from Plasmodium falciparum in complex with D-Serine [Plasmodium falciparum 3D7],3KOD_D DTD from Plasmodium falciparum in complex with D-Serine [Plasmodium falciparum 3D7],3KOD_E DTD from Plasmodium falciparum in complex with D-Serine [Plasmodium falciparum 3D7],3KOD_F DTD from Plasmodium falciparum in complex with D-Serine [Plasmodium falciparum 3D7],3LMT_A Crystal structure of DTD from Plasmodium falciparum [Plasmodium falciparum 3D7],3LMT_B Crystal structure of DTD from Plasmodium falciparum [Plasmodium falciparum 3D7],3LMT_C Crystal structure of DTD from Plasmodium falciparum [Plasmodium falciparum 3D7],3LMT_D Crystal structure of DTD from Plasmodium falciparum [Plasmodium falciparum 3D7],3LMT_E Crystal structure of DTD from Plasmodium falciparum [Plasmodium falciparum 3D7],3LMT_F Crystal structure of DTD from Plasmodium falciparum [Plasmodium falciparum 3D7],3LMU_A Crystal structure of DTD from Plasmodium falciparum [Plasmodium falciparum 3D7],3LMU_B Crystal structure of DTD from Plasmodium falciparum [Plasmodium falciparum 3D7],3LMU_C Crystal structure of DTD from Plasmodium falciparum [Plasmodium falciparum 3D7],3LMU_D Crystal structure of DTD from Plasmodium falciparum [Plasmodium falciparum 3D7],3LMU_E Crystal structure of DTD from Plasmodium falciparum [Plasmodium falciparum 3D7],3LMU_F Crystal structure of DTD from Plasmodium falciparum [Plasmodium falciparum 3D7],3LMU_G Crystal structure of DTD from Plasmodium falciparum [Plasmodium falciparum 3D7],3LMU_H Crystal structure of DTD from Plasmodium falciparum [Plasmodium falciparum 3D7],3LMV_A D-Tyr-tRNA(Tyr) Deacylase from plasmodium falciparum in complex with hepes [Plasmodium falciparum 3D7],3LMV_B D-Tyr-tRNA(Tyr) Deacylase from plasmodium falciparum in complex with hepes [Plasmodium falciparum 3D7],3LMV_C D-Tyr-tRNA(Tyr) Deacylase from plasmodium falciparum in complex with hepes [Plasmodium falciparum 3D7],3LMV_D D-Tyr-tRNA(Tyr) Deacylase from plasmodium falciparum in complex with hepes [Plasmodium falciparum 3D7],3LMV_E D-Tyr-tRNA(Tyr) Deacylase from plasmodium falciparum in complex with hepes [Plasmodium falciparum 3D7],3LMV_F D-Tyr-tRNA(Tyr) Deacylase from plasmodium falciparum in complex with hepes [Plasmodium falciparum 3D7],4NBI_A D-aminoacyl-tRNA deacylase (DTD) from Plasmodium falciparum in complex with D-tyrosyl-3'-aminoadenosine at 1.86 Angstrom resolution [Plasmodium falciparum 3D7],4NBI_B D-aminoacyl-tRNA deacylase (DTD) from Plasmodium falciparum in complex with D-tyrosyl-3'-aminoadenosine at 1.86 Angstrom resolution [Plasmodium falciparum 3D7],4NBJ_A D-aminoacyl-tRNA deacylase (DTD) from Plasmodium falciparum in complex with D-tyrosyl-3'-aminoadenosine at 2.20 Angstrom resolution [Plasmodium falciparum 3D7],4NBJ_B D-aminoacyl-tRNA deacylase (DTD) from Plasmodium falciparum in complex with D-tyrosyl-3'-aminoadenosine at 2.20 Angstrom resolution [Plasmodium falciparum 3D7],4NBJ_C D-aminoacyl-tRNA deacylase (DTD) from Plasmodium falciparum in complex with D-tyrosyl-3'-aminoadenosine at 2.20 Angstrom resolution [Plasmodium falciparum 3D7],4NBJ_D D-aminoacyl-tRNA deacylase (DTD) from Plasmodium falciparum in complex with D-tyrosyl-3'-aminoadenosine at 2.20 Angstrom resolution [Plasmodium falciparum 3D7],4NBJ_E D-aminoacyl-tRNA deacylase (DTD) from Plasmodium falciparum in complex with D-tyrosyl-3'-aminoadenosine at 2.20 Angstrom resolution [Plasmodium falciparum 3D7],4NBJ_F D-aminoacyl-tRNA deacylase (DTD) from Plasmodium falciparum in complex with D-tyrosyl-3'-aminoadenosine at 2.20 Angstrom resolution [Plasmodium falciparum 3D7],4NBJ_G D-aminoacyl-tRNA deacylase (DTD) from Plasmodium falciparum in complex with D-tyrosyl-3'-aminoadenosine at 2.20 Angstrom resolution [Plasmodium falciparum 3D7],4NBJ_H D-aminoacyl-tRNA deacylase (DTD) from Plasmodium falciparum in complex with D-tyrosyl-3'-aminoadenosine at 2.20 Angstrom resolution [Plasmodium falciparum 3D7],5J61_A D-aminoacyl-tRNA deacylase (DTD) from Plasmodium falciparum in complex with glycyl-3'-aminoadenosine at 2.10 Angstrom resolution [Plasmodium falciparum 3D7],5J61_B D-aminoacyl-tRNA deacylase (DTD) from Plasmodium falciparum in complex with glycyl-3'-aminoadenosine at 2.10 Angstrom resolution [Plasmodium falciparum 3D7],5J61_C D-aminoacyl-tRNA deacylase (DTD) from Plasmodium falciparum in complex with glycyl-3'-aminoadenosine at 2.10 Angstrom resolution [Plasmodium falciparum 3D7],5J61_D D-aminoacyl-tRNA deacylase (DTD) from Plasmodium falciparum in complex with glycyl-3'-aminoadenosine at 2.10 Angstrom resolution [Plasmodium falciparum 3D7],5J61_E D-aminoacyl-tRNA deacylase (DTD) from Plasmodium falciparum in complex with glycyl-3'-aminoadenosine at 2.10 Angstrom resolution [Plasmodium falciparum 3D7],5J61_F D-aminoacyl-tRNA deacylase (DTD) from Plasmodium falciparum in complex with glycyl-3'-aminoadenosine at 2.10 Angstrom resolution [Plasmodium falciparum 3D7],5J61_G D-aminoacyl-tRNA deacylase (DTD) from Plasmodium falciparum in complex with glycyl-3'-aminoadenosine at 2.10 Angstrom resolution [Plasmodium falciparum 3D7],5J61_H D-aminoacyl-tRNA deacylase (DTD) from Plasmodium falciparum in complex with glycyl-3'-aminoadenosine at 2.10 Angstrom resolution [Plasmodium falciparum 3D7]
1J7G_A	3.15e-18	1520	1656	16	143	Structure of YihZ from Haemophilus influenzae (HI0670), a D-Tyr-tRNA(Tyr) deacylase [Haemophilus influenzae Rd KW20]
1JKE_A	2.93e-15	1520	1655	16	143	D-Tyr tRNATyr deacylase from Escherichia coli [Escherichia coli],1JKE_B D-Tyr tRNATyr deacylase from Escherichia coli [Escherichia coli],1JKE_C D-Tyr tRNATyr deacylase from Escherichia coli [Escherichia coli],1JKE_D D-Tyr tRNATyr deacylase from Escherichia coli [Escherichia coli]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P08004|CHS1_YEAST	2.42e-317	661	1518	234	1115	Chitin synthase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=CHS1 PE=1 SV=2
sp|P30572|CHS2_CANAX	1.57e-238	790	1529	244	999	Chitin synthase 2 OS=Candida albicans OX=5476 GN=CHS2 PE=2 SV=2
sp|P30583|CHSC_EMENI	3.70e-224	788	1530	182	917	Chitin synthase C OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=chsC PE=3 SV=3
sp|P30588|CHS3_NEUCR	1.74e-216	780	1518	148	875	Chitin synthase 3 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=chs-3 PE=3 SV=2
sp|P30601|CHS2_EXODE	8.61e-216	788	1518	191	908	Chitin synthase 2 OS=Exophiala dermatitidis OX=5970 GN=CHS2 PE=3 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000053	0.000000

TMHMM  Annotations     

Start	End
1166	1188
1209	1231
1241	1263
1272	1294
1323	1342
1349	1371
1450	1472
1497	1519