CAZyme Information: NEUTE1DRAFT_132459-t26_1-p1

Basic Information

• Species: Neurospora tetrasperma
• Lineage: Ascomycota; Sordariomycetes; ; Sordariaceae; Neurospora; Neurospora tetrasperma
• CAZyme ID: NEUTE1DRAFT_132459-t26_1-p1
• CAZy Family: GH132
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1407		135803.87	4.0572

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_NtetraspermaFGSC2508	10380	510951	0	10380

• Gene Location: location=GL891382:832902-837194(+)

Full Sequence      

MHKSLVAAAVLAATARAHALTEAKVNVYLGQKGDARLRDHCDQANFDYVTIGAHCDATYY
TNGTTSGQMNGKCSIVASDIKHCQDKGKKVLLSLDGVEHMGSRFSLSSEAKAEEFASFLW
GAFGPYDAKWTGPRPFDYAGHRVSVDGFNLDGELKLNGAGEGAYAAMAKKLRELYNGNGE
LLLTAAPGCSLDDVKLKAIFDNAQFDALFIQFYNNPSCEAGSASGFNYLQWEQAIAAGMS
KEAKLFIGLAGASDAAGSGYIEPLEAAALINTYKTRSSFGGAMVLDAFRGQTLANGMTFL
DVINTVVSSAEAVDLSSEFCEDESALPKVPSVTEGSAGGFFTVADPSAITSGPVVLPSGG
SSEDEVCEDENVIPKVPSVTDGAHEVNPTIVDTSIITSVPVALPSGDRSEIIGGSPATED
DVCEGEIMTEDPLRSGVVPTGIMPTGALPSGVLPSGDRSEIIGAIPSGSVPLGSAPSGLV
PSGSIPLGSAPSGLVPSGTVPSGDRSDIIGAIPSGSIPLGSAPSGLVPSGAVPLGSAPSG
LVPSGAVPSGDRSEIIGSPADEDDVCEGEDPVRSGLVPSGAVPSGAVPSGAVPSGDRSDI
IGAIPSGSIPLGSAPSGLVPSGAVPSGDRSEIIGAIPSGSIPLGSVPSGAAPSGDRSEII
GAIPSGSIPLGSAPSGAVPSGLVPSGIVPSGAVPSGDRSEIIGSPADEDDYCEGEITPED
PVRSGLVPSGIVPTGAVPTGLVPSGAVIGSTVPGGVIPSGVAPGGILPSGVVSSVGSKVT
GPIDGDNVALPSVGLPSGAIASGVVPSGVVPSGVVSSIGSKVTGPIDGDNVALPSVGLPS
GDLPSGVVPSGVVPSGVLSSVGSKVTGPINGHNVAVPSAGVPSGVVPSGVLSNVGSKVTG
PIDGDNVVPTGILPSGSVPSGVVSSVVSMVTADPINGDKIADPSAVTAPAEWTTSTIYAT
TTSTITSCAPEVTDCPAKIGQVTTVTVPIGVTVCPVTATETAARAPTGIFTSVPVESIPA
GFTTSTVYSTTTSTIASCAPEMTDCAGKIGQVTTVIVPIGVTVCPVTATETAARAPTGIM
TSVPVESIPAGYTTSTVYSTATSTIASCAPEMTDCAGKIGQVTTIIVPVGVTVCPITEAF
PPATSVPAAPAAVPTGAASVPAVSAVPTGGAGVPAVSAPVVPSGVADVPAVSAPAVPTGG
AGVPAVSAPVVPTGGAGVPAVSAPVVPSGVAGVPAVSAPAVPSGGAGVPAVSAPAVPSGG
ADVPAAPSNGAPGAGVNKVATSSIVSVSSMPFTTITVAKPAASAPGAPGAPGAGVPAESA
AVPAGGAPAVPSAVNAPVVPSGAVPTGTGVSVAPSSAPSTYSMPAPPAQTEPATGSEPSE
VPVTAGAGRNVVAMGVPALMAALVLAL

Enzyme Prediction     

No EC number prediction in NEUTE1DRAFT_132459-t26_1-p1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH18	24	252	5.1e-18	0.6554054054054054

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
119356	GH18_hevamine_XipI_class_III	1.28e-84	23	303	1	278	This conserved domain family includes xylanase inhibitor Xip-I, and the class III plant chitinases such as hevamine, concanavalin B, and PPL2, all of which have a glycosyl hydrolase family 18 (GH18) domain. Hevamine is a class III endochitinase that hydrolyzes the linear polysaccharide chains of chitin and peptidoglycan and is important for defense against pathogenic bacteria and fungi. PPL2 (Parkia platycephala lectin 2) is a class III chitinase from Parkia platycephala seeds that hydrolyzes beta(1-4) glycosidic bonds linking 2-acetoamido-2-deoxy-beta-D-glucopyranose units in chitin.
395573	Glyco_hydro_18	4.90e-12	24	266	1	239	Glycosyl hydrolases family 18.
237865	PRK14951	2.49e-09	1130	1255	369	491	DNA polymerase III subunits gamma and tau; Provisional
223021	PHA03247	7.47e-09	1135	1378	2647	2881	large tegument protein UL36; Provisional
223021	PHA03247	1.25e-08	1058	1381	2673	3004	large tegument protein UL36; Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AEO65134.1|CBM50|GH18	2.70e-55	11	306	8	335
AEO54851.1|CBM50|GH18	1.25e-53	21	310	19	341
QLI68859.1|GH18	9.24e-50	25	313	17	321
CDP24384.1|CBM50|GH18	9.28e-49	10	290	7	325
VBB73572.1|CBM50|GH18	9.28e-49	10	290	7	325

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2XVN_A	1.58e-37	27	287	5	286	A. fumigatus chitinase A1 phenyl-methylguanylurea complex [Aspergillus fumigatus],2XVN_B A. fumigatus chitinase A1 phenyl-methylguanylurea complex [Aspergillus fumigatus],2XVN_C A. fumigatus chitinase A1 phenyl-methylguanylurea complex [Aspergillus fumigatus]
4TX6_A	1.62e-37	27	287	6	287	AfChiA1 in complex with compound 1 [Aspergillus fumigatus A1163],4TX6_B AfChiA1 in complex with compound 1 [Aspergillus fumigatus A1163]
2XTK_A	1.62e-37	27	287	6	287	ChiA1 from Aspergillus fumigatus in complex with acetazolamide [Aspergillus fumigatus A1163],2XTK_B ChiA1 from Aspergillus fumigatus in complex with acetazolamide [Aspergillus fumigatus A1163],2XUC_A Natural product-guided discovery of a fungal chitinase inhibitor [Aspergillus fumigatus],2XUC_B Natural product-guided discovery of a fungal chitinase inhibitor [Aspergillus fumigatus],2XUC_C Natural product-guided discovery of a fungal chitinase inhibitor [Aspergillus fumigatus],2XVP_A ChiA1 from Aspergillus fumigatus, apostructure [Aspergillus fumigatus A1163],2XVP_B ChiA1 from Aspergillus fumigatus, apostructure [Aspergillus fumigatus A1163]
2UY2_A	2.20e-32	25	310	8	290	ScCTS1_apo crystal structure [Saccharomyces cerevisiae],2UY3_A ScCTS1_8-chlorotheophylline crystal structure [Saccharomyces cerevisiae],2UY4_A ScCTS1_acetazolamide crystal structure [Saccharomyces cerevisiae],2UY5_A ScCTS1_kinetin crystal structure [Saccharomyces cerevisiae],4TXE_A ScCTS1 in complex with compound 5 [Saccharomyces cerevisiae]
2GSJ_A	3.78e-24	27	288	5	256	cDNA cloning and 1.75A crystal structure determination of PPL2, a novel chimerolectin from Parkia platycephala seeds exhibiting endochitinolytic activity [Parkia platycephala]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|A2QUQ2|CHIA1_ASPNC	2.07e-36	19	336	24	352	Endochitinase A OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) OX=425011 GN=ctcA PE=2 SV=1
sp|P54197|CHI2_COCP7	3.68e-36	27	307	33	337	Endochitinase 2 OS=Coccidioides posadasii (strain C735) OX=222929 GN=CTS2 PE=3 SV=2
sp|Q1EAR5|CHI2_COCIM	4.26e-36	27	307	33	337	Endochitinase 2 OS=Coccidioides immitis (strain RS) OX=246410 GN=CTS2 PE=3 SV=2
sp|Q4WEP7|CHIA1_ASPFU	1.16e-34	4	336	7	360	Endochitinase A1 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=chiA1 PE=3 SV=1
sp|Q873Y0|CHIA1_ASPFM	3.73e-34	4	287	7	314	Endochitinase A1 OS=Neosartorya fumigata OX=746128 GN=chiA1 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.000247	0.999724	CS pos: 19-20. Pr: 0.9109

TMHMM  Annotations     

There is no transmembrane helices in NEUTE1DRAFT_132459-t26_1-p1.