CAZyme Information: NEUTE1DRAFT_130058-t26_1-p1

Basic Information

• Species: Neurospora tetrasperma
• Lineage: Ascomycota; Sordariomycetes; ; Sordariaceae; Neurospora; Neurospora tetrasperma
• CAZyme ID: NEUTE1DRAFT_130058-t26_1-p1
• CAZy Family: GH13
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
676		75355.39	7.7623

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_NtetraspermaFGSC2508	10380	510951	0	10380

• Gene Location: location=GL891304:4435676-4438122(-)

Full Sequence      

MAPPQAEDPRPTLVAGNSYLTDPFQDPSSDSASSQGPSRRPSSENPPSPTVPAPPVVAAP
PAVPAPVVPASARAPAAPVALPPPQIQLPVDDITPAPAAPPAGEVPQQEFDEKTGGVLNP
AGDVEQGRAAAAPAGADPEKSGSPPRKSRNPFKRGYWAFRNTYCPKEEPGLVFPTGPDDE
EKLRYVHTNRIPLYVFGIISFLTLSAGMWLFAVCSPIFAWYGVFVGFLNIYLIISYLVGV
VGRDWDYDGHKKIVEEFPINEETAPTVDVYLPCCSEPLEILENTYKHVIKLDWPAAKLKV
YVLDDSASDAVRTLAESYGFNYIVRDDRPRLRKAGNLRWAFARTQGDFFAIFDADFCPRP
DFLRELVVEHMADDKTAIIQSPQYFRVTDDQTWVEQGAGATQELFYRVVQVNRNRWGASI
CVGSNAVYRRAALEEVGGTAEIGFSEDVHTGFGAVDRGWKVKYVPLCLATGICPNTPRSF
FSQQMRWARGSTTLLTTKHFWTSNLNFMQKLCYLCGLLYYSAVSLGIFISPIPGTLLLAF
RPIYFKYYNLAFAIPSIVYGAVLFRFWAKAKYGFNVQHIMVVQSYAYLTAIKDRLFGIEL
LWAASGDKKAHKSNKYRNMRVLCTLWTILNVGGMITAVVYRVGFHGMEWYNTLPLIILSA
YNLYISHYFIFASWKW

Enzyme Prediction     

No EC number prediction in NEUTE1DRAFT_130058-t26_1-p1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	269	437	1e-26	0.9882352941176471

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
133043	CESA_CelA_like	2.96e-105	265	495	1	234	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose. Family of proteins related to Agrobacterium tumefaciens CelA and Gluconacetobacter xylinus BscA. These proteins are involved in the elongation of the glucan chain of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues. They are putative catalytic subunit of cellulose synthase, which is a glycosyltransferase using UDP-glucose as the substrate. The catalytic subunit is an integral membrane protein with 6 transmembrane segments and it is postulated that the protein is anchored in the membrane at the N-terminal end.
224136	BcsA	8.98e-45	202	603	5	404	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility].
236918	bcsA	2.52e-41	258	533	253	523	cellulose synthase catalytic subunit; Provisional
133059	CESA_CaSu_A2	3.56e-34	265	491	1	232	Cellulose synthase catalytic subunit A2 (CESA2) is a catalytic subunit or a catalytic subunit substitute of the cellulose synthase complex. Cellulose synthase (CESA) catalyzes the polymerization reaction of cellulose using UDP-glucose as the substrate. Cellulose is an aggregate of unbranched polymers of beta-1,4-linked glucose residues, which is an abundant polysaccharide produced by plants and in varying degrees by several other organisms including algae, bacteria, fungi, and even some animals. Genomes from higher plants harbor multiple CESA genes. There are ten in Arabidopsis. At least three different CESA proteins are required to form a functional complex. In Arabidopsis, CESA1, 3 and 6 and CESA4, 7 and 8, are required for cellulose biosynthesis during primary and secondary cell wall formation. CESA2 is very closely related to CESA6 and is viewed as a prime substitute for CESA6. They functionally compensate each other. The cesa2 and cesa6 double mutant plants were significantly smaller, while the single mutant plants were almost normal.
133045	CESA_like	6.78e-33	269	447	1	180	CESA_like is the cellulose synthase superfamily. The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CAP68353.1|GT2	0.0	105	676	80	651
VBB86309.1|GT2	0.0	105	676	80	651
CDP31824.1|GT2	0.0	105	676	80	651
AGY80099.1|GH12|GT2	0.0	152	676	361	884
AEO69079.1|GH12|GT2	0.0	105	664	293	879

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7LBY_A	9.56e-36	249	561	250	574	Chain A, Cellulose synthase catalytic subunit [UDP-forming] [Escherichia coli K-12]
5EJ1_A	1.10e-31	258	514	121	399	Chain A, Putative cellulose synthase [Cereibacter sphaeroides 2.4.1]
4HG6_A	1.35e-31	258	514	133	411	Chain A, Cellulose Synthase Subunit A [Cereibacter sphaeroides]
4P00_A	1.35e-31	258	514	134	412	Chain A, Cellulose Synthase A subunit [Cereibacter sphaeroides 2.4.1],4P02_A Chain A, Cellulose Synthase subunit A [Cereibacter sphaeroides 2.4.1],5EIY_A Chain A, Putative cellulose synthase [Cereibacter sphaeroides 2.4.1],5EJZ_A Chain A, Putative cellulose synthase [Cereibacter sphaeroides 2.4.1]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P58932|BCSA_XANAC	7.72e-40	258	520	146	411	Cellulose synthase catalytic subunit [UDP-forming] OS=Xanthomonas axonopodis pv. citri (strain 306) OX=190486 GN=bcsA PE=3 SV=1
sp|Q9WX61|BCSA3_KOMXY	6.76e-39	258	558	142	438	Cellulose synthase 1 catalytic subunit [UDP-forming] OS=Komagataeibacter xylinus OX=28448 GN=bcsAI PE=3 SV=1
sp|P19449|BCSA1_KOMXY	1.34e-37	258	560	142	449	Cellulose synthase catalytic subunit [UDP-forming] OS=Komagataeibacter xylinus OX=28448 GN=bcsA PE=1 SV=1
sp|Q9RBJ2|BCSA4_KOMXY	1.45e-37	256	574	135	461	Putative cellulose synthase 2 OS=Komagataeibacter xylinus OX=28448 GN=bcsABII-A PE=3 SV=1
sp|Q9WX75|BCSA5_KOMXY	1.45e-37	256	574	135	461	Putative cellulose synthase 3 OS=Komagataeibacter xylinus OX=28448 GN=bcsABII-B PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000053	0.000000

TMHMM  Annotations     

Start	End
191	213
217	239
511	533
548	567
622	644
649	671