CAZyme Information: MRET_0069-t46_1-p1

Basic Information

• Species: Malassezia restricta
• Lineage: Basidiomycota; Malasseziomycetes; ; Malasseziaceae; Malassezia; Malassezia restricta
• CAZyme ID: MRET_0069-t46_1-p1
• CAZy Family: AA1
• CAZyme Description: dehydrogenase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
622	CP030251|CGC3	68574.63	6.8497

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_MrestrictaKCTC27527	4544	N/A	138	4406

• Gene Location: location=CP030251:125997-127865(+)

Full Sequence      

MTRFISWAVVSVAVLCVSQVSGFYNETRVFDRRQTTGNGWDLDNKSYDYVIVGGGTAGLV
LANRLSADGSNSVAVIEAGNSGYDDNNKFIVPSAMLYDSGTNTQYDWQFKTTAQKHMNGR
KAAWPRGKVLGGSSAINGLYYVRPSDAEMNAWADLAGGNAYDHWGWDSFFGFFKRSEKFQ
TPLKSVQDQAHIHYDDGSHGHHGPIHTTWPAITYGPVGAFIESANKAGVKMNKNGYDGKN
QGVYLALSSLNKDNWQRSFSRNEYLDPIGDRKNLHVLTGHTVTQILFDRSDKNNVQATGV
HYKAAANEYEHTLHANKEVILSAGSINSPQLLQLSGVGPSGLLQSLGIDVVVDLPGVGEN
LQDHVMAGMSFSVKNDKDVPPQKVTGNKKTDSYVNSAVSYVAFHNIFNDADAFRGKIQAR
VKAIPDELNVDDSVREGYRAVYDKIANDLFYSNVSPVEVLGNVMFGSISLQAALQHPLSR
GNIRITSKNPFDYPRINPNYFREDIDLKILREAFKLIREITQQPPLKDHIASENWPGNGV
QSNEQWEDWIRNAAGTEYHPSSTCAMLPRNKGGVVNPDLKVYGTRNLRVVDASVPPLALS
CHLESVVYALAEAAAEIILNHN

Enzyme Prediction     

No EC number prediction in MRET_0069-t46_1-p1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
AA3	45	620	8.3e-187	0.9964788732394366

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
235000	PRK02106	5.26e-130	44	596	3	509	choline dehydrogenase; Validated
225186	BetA	2.27e-104	44	600	5	515	Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only].
398739	GMC_oxred_C	2.86e-37	477	608	1	137	GMC oxidoreductase. This domain found associated with pfam00732.
366272	GMC_oxred_N	4.03e-37	118	364	15	216	GMC oxidoreductase. This family of proteins bind FAD as a cofactor.
215420	PLN02785	2.65e-25	46	594	55	552	Protein HOTHEAD

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AXA48849.1|AA3_2	0.0	1	622	1	622
AYO41661.1|AA3_2	0.0	1	622	1	622
SHO78725.1|AA3_2	2.09e-299	1	621	1	618
CDI55496.1|AA3_2	2.28e-207	32	619	39	627
CBQ69373.1|AA3_2	8.96e-206	32	619	50	638

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4YNT_A	1.29e-86	42	618	1	564	Crystal structure of Aspergillus flavus FAD glucose dehydrogenase [Aspergillus flavus NRRL3357],4YNU_A Crystal structure of Aspergillus flavus FADGDH in complex with D-glucono-1,5-lactone [Aspergillus flavus NRRL3357]
6XUT_A	3.13e-78	42	618	12	587	Chain A, Oligosaccharide dehydrogenase [Trametes cinnabarina],6XUU_A Chain A, Oligosaccharide dehydrogenase [Trametes cinnabarina],6XUV_A Chain A, Oligosaccharide dehydrogenase [Trametes cinnabarina]
4H7U_A	9.10e-73	47	618	41	597	Crystal structure of pyranose dehydrogenase from Agaricus meleagris, wildtype [Leucoagaricus meleagris]
6ZE2_A	2.95e-72	44	618	3	582	Chain A, FAD-dependent oxidoreductase [Thermochaetoides thermophila DSM 1495],6ZE2_B Chain B, FAD-dependent oxidoreductase [Thermochaetoides thermophila DSM 1495],6ZE3_A Chain A, FAD-dependent oxidoreductase [Thermochaetoides thermophila DSM 1495],6ZE4_A Chain A, FAD-dependent oxidoreductase [Thermochaetoides thermophila DSM 1495],6ZE4_B Chain B, FAD-dependent oxidoreductase [Thermochaetoides thermophila DSM 1495],6ZE5_A Chain A, FAD-dependent oxidoreductase [Thermochaetoides thermophila DSM 1495],6ZE5_B Chain B, FAD-dependent oxidoreductase [Thermochaetoides thermophila DSM 1495],6ZE6_A Chain A, FAD-dependent oxidoreductase [Thermochaetoides thermophila DSM 1495],6ZE6_B Chain B, FAD-dependent oxidoreductase [Thermochaetoides thermophila DSM 1495],6ZE7_A Chain A, FAD-dependent oxidoreductase [Thermochaetoides thermophila DSM 1495],6ZE7_B Chain B, FAD-dependent oxidoreductase [Thermochaetoides thermophila DSM 1495],7AA2_A Chain A, FAD-dependent oxidoreductase [Thermochaetoides thermophila DSM 1495],7AA2_B Chain B, FAD-dependent oxidoreductase [Thermochaetoides thermophila DSM 1495]
5OC1_A	3.19e-68	47	618	2	561	Crystal structure of aryl-alcohol oxidase from Pleurotus eryngii in complex with p-anisic acid [Pleurotus eryngii]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q5GMY3|GMCH_MALSM	3.71e-300	1	621	1	618	GMC oxidoreductase family protein Mala s 12.0101 OS=Malassezia sympodialis OX=76777 PE=1 SV=2
sp|M5EAX2|GMCH_MALS4	3.71e-300	1	621	1	618	GMC oxidoreductase family protein Mala s 12 OS=Malassezia sympodialis (strain ATCC 42132) OX=1230383 GN=MSY001_2108 PE=1 SV=1
sp|Q4A0Q1|BETA_STAS1	1.64e-82	45	618	3	533	Oxygen-dependent choline dehydrogenase OS=Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41) OX=342451 GN=betA PE=3 SV=1
sp|A0A2H3D1U1|ARMD5_ARMGA	5.42e-81	42	618	35	629	Dehydrogenase ARMGADRAFT_1018426 OS=Armillaria gallica OX=47427 GN=ARMGADRAFT_1018426 PE=1 SV=1
sp|Q9X2M2|BETA_STAXY	5.26e-79	45	618	3	533	Oxygen-dependent choline dehydrogenase OS=Staphylococcus xylosus OX=1288 GN=betA PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.000523	0.999449	CS pos: 22-23. Pr: 0.9750

TMHMM  Annotations     

There is no transmembrane helices in MRET_0069-t46_1-p1.