CAZyme Information: KLU90669.1

Basic Information

• Species: Magnaporthiopsis poae
• Lineage: Ascomycota; Sordariomycetes; ; Magnaporthaceae; Magnaporthiopsis; Magnaporthiopsis poae
• CAZyme ID: KLU90669.1
• CAZy Family: GH72
• CAZyme Description: Chitin synthase [Source:UniProtKB/TrEMBL;Acc:A0A0C4ECT6]

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
818	GL876975|CGC1	92924.53	8.9911

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_MpoaeATCC64411	12363	644358	200	12163

• Gene Location: location=GL876975:888039-890569(+)

Full Sequence      

MGGGSPVSCDDDDEDSWIQRQQPNATPAGGLKRYATRKVKLVQGSVLSINYNVPSAIRNA
VQPKYRDLEGTNEEFVKIRYTAATCDPDEFTLKNGYDLRPWMYSRHTELLIAITYYNEDK
MLTSRTLHSVMQNIRDIVNLKKSTLWHRGGPAWQKIVVVLLFDGVDNVDHGVLDVLATMG
VYQHGVTERVVDGHETQAHVFEYTTQLSVTPDSRLVKPVTEDSTTLPPIQVILCMKTKRA
GKINSHRWLYNAFGRILNPEVIVTVDTGTRLCRYALLEMWAAFYNDKDLGAACGEIRCHT
GKFRSRAGLVNPIVASQNFEYVVAFQLERSFEAAIGWLTVLPGAFSAYRFRAIVGYPLDR
YFHGDPSLARIWRKGGARATAFGANRFLAEDRVVAYELLAGKGKKWHSDFINSARAETDI
PCTTADFISQRRRWLNGAFTSTLYSIGRFYKMYRSGHSIARLAAFHVELAYNLVTFLVAW
FSLAGYLLTMFVVNDVTGNPPDGSGAYAWPFGPATPVFNGIIQFVYILVVVLQFVLALGS
HPRRERKLYLLSFIIFSFVQLYLFLNLIYLVKRLLDFRREGAGAESSYNYINEYYSDVGP
WTVLITGVSVFGVYIAAGILHLDMWHLFTSYASYLFVLASYINILSIYAFSNTHDITWGR
KSGRQDLNDDFKHPLHPPARASASSQGGVVIEEVQKPQEDIDTQFEAVVKRALTPYVPPT
KEYGDGGAKSRNTTPEEDFKSFRTKLVGVYIFSNFLMCAVVLNDSFQSLSFLGDPYWHKI
WFFRVWMWANAGVLLMRLAGCCWFTVFHRGWRLLFWRY

Enzyme Prediction     

EC	2.4.1.16:26

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	115	283	2.1e-60	0.9938650306748467

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
396286	Chitin_synth_1	1.07e-81	115	283	1	163	Chitin synthase. This region is found commonly in chitin synthases classes I, II and III. Chitin a linear homopolymer of GlcNAc residues, it is an important component of the cell wall of fungi and is synthesized on the cytoplasmic surface of the cell membrane by membrane bound chitin synthases.
133033	Chitin_synth_C	4.34e-57	111	439	1	242	C-terminal domain of Chitin Synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin. Chitin synthase, also called UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyltransferase, catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of GlcNAc residues formed by covalent beta-1,4 linkages. Chitin is an important component of the cell wall of fungi and bacteria and it is synthesized on the cytoplasmic surface of the cell membrane by membrane bound chitin synthases. Studies with fungi have revealed that most of them contain more than one chitin synthase gene. At least five subclasses of chitin synthases have been identified.
400626	Chitin_synth_1N	4.93e-27	38	114	1	70	Chitin synthase N-terminal. This is the N-terminal domain of Chitin synthase (pfam01644).
224136	BcsA	1.27e-22	226	569	109	402	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility].
133045	CESA_like	3.02e-15	251	354	71	167	CESA_like is the cellulose synthase superfamily. The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
VBB75132.1|GT2	3.69e-298	14	804	123	905
AEO55935.1|GT2	1.97e-295	12	804	112	895
AEQ16474.1|GT2	5.68e-295	1	804	124	916
QBZ56648.1|GT2	5.68e-295	1	804	124	916
CAP72673.1|GT2	6.19e-295	14	804	123	898

PDB Hits     

KLU90669.1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P29070|CHS1_NEUCR	3.84e-295	12	804	121	904	Chitin synthase 1 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=chs-1 PE=3 SV=2
sp|P54267|CHSG_ASPFU	1.26e-294	15	804	122	898	Chitin synthase G OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=chsG PE=2 SV=2
sp|Q00757|CHSB_EMENI	2.18e-286	15	804	126	903	Chitin synthase B OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=chsB PE=2 SV=2
sp|P30602|CHS3_EXODE	3.92e-279	12	775	114	866	Chitin synthase 3 OS=Exophiala dermatitidis OX=5970 GN=CHS3 PE=3 SV=2
sp|Q92197|CHSC_ASPFU	2.39e-269	15	804	106	880	Chitin synthase C OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=chsC PE=3 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000059	0.000000

TMHMM  Annotations     

Start	End
471	493
516	538
548	570
598	620
630	652
746	763
785	807