CAZyme Information: KIW92265.1

Basic Information

• Species: Cladophialophora bantiana
• Lineage: Ascomycota; Eurotiomycetes; ; Herpotrichiellaceae; Cladophialophora; Cladophialophora bantiana
• CAZyme ID: KIW92265.1
• CAZy Family: GH17
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
779	KN846989|CGC3	89192.58	8.8600

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_CbantianaCBS173.52	12817	1442370	55	12762

• Gene Location: location=KN846989:949883-952356(+)

Full Sequence      

MSTPNSTLRQRGPKEKNKPVASGEKDDEVLNEALSNVQKTVSKEWDYKLALGVIAALAFA
TRFFGISHPNEVVFDEVHFGKFASYYLQRTYFFDVHPPFGKLLFALVGWLVGYDGHFLFD
NIGESYITNNVPYLAFRGLPAFLGALTVVVVYLIMWESGYSLPACVLAAGLVLFDNSHVG
QTRLILLDATLVFFVSLSIYCYIRFYKQRHDPFGRKWWKWLLLCGFCMSCVISTKYVGAF
TFFTIGCAVLIDLWDLLDINRKGGALDLFTFGKHFVARALGLIIIPFFFYLFWFQVHFAI
LTRSGPGDDFMTPEFQETLSDNLMHQASIDIQYYDYITLRHKDTKVYLHSHPDRYPLRYD
DGRISSQGQQVTGYPFNDTNNEWQILPNAQHPDPAMAGKPVLNGDIVKLRHVVTNTMLLT
HDVASPYFPTNQEFTTVPLEVAAGDRHNDTLFEIRMEQGKKGSPFKTMSGQFKLIHYPTK
VAMWTHTTPLPDWAFKQAEINGNKNAQQSSNIWYVDDIPNLPEDSPRRIKEVKKTKSLPF
YRKYIELQRAMFYHNNALTASHPYATQPYQWPFLLRGVSFWTQDSTKQQIYFLGNPIGYW
IASALLAVFAGILGADQLSLRRGIDALDRRTRSRLYNSTGFFFLCWAAHYFPFYLMGRQL
FLHHYLPAHLASCLVTGALIEFIFNVDPAIDDDTHHAPQQKKDKVTGKIPEKARKHFQTA
AERLKGQSMLGTWAATVVILAAVLYGFYFFFPLTYGWPGLTPAQVNARKWLGYDLHFAK

Enzyme Prediction     

EC	2.4.1.109:8

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT39	54	298	5.7e-72	0.9910313901345291

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
224839	PMT1	0.0	46	779	22	699	Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones].
396786	PMT	2.16e-82	53	302	2	245	Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families.
406576	PMT_4TMC	1.53e-78	542	771	1	197	C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes.
397103	MIR	4.46e-13	339	496	3	164	MIR domain. The MIR (protein mannosyltransferase, IP3R and RyR) domain is a domain that may have a ligand transferase function.
197746	MIR	2.94e-09	329	388	2	57	Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
SMR42986.1|GT39	0.0	1	779	1	779
SMR45157.1|GT39	0.0	1	779	1	779
SMY20320.1|GT39	0.0	1	779	1	779
SMQ46634.1|GT39	0.0	1	779	1	779
APA05800.1|GT39	0.0	1	779	1	771

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6P25_A	1.12e-105	48	774	50	728	Structure of S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the sugar donor and a peptide acceptor [Saccharomyces cerevisiae W303],6P2R_A Structure of S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the sugar donor [Saccharomyces cerevisiae W303]
6P25_B	1.25e-89	53	668	70	681	Structure of S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the sugar donor and a peptide acceptor [Saccharomyces cerevisiae W303],6P2R_B Structure of S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the sugar donor [Saccharomyces cerevisiae W303]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q59X23|PMT4_CANAL	5.32e-249	7	779	4	755	Dolichyl-phosphate-mannose--protein mannosyltransferase 4 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=PMT4 PE=2 SV=2
sp|O42933|PMT4_SCHPO	4.14e-241	20	771	32	767	Dolichyl-phosphate-mannose--protein mannosyltransferase 4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=ogm4 PE=3 SV=1
sp|P46971|PMT4_YEAST	1.11e-239	37	779	42	762	Dolichyl-phosphate-mannose--protein mannosyltransferase 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=PMT4 PE=1 SV=1
sp|F1Q8R9|POMT2_DANRE	2.35e-114	51	771	71	751	Protein O-mannosyl-transferase 2 OS=Danio rerio OX=7955 GN=pomt2 PE=1 SV=1
sp|Q8R2R1|POMT1_MOUSE	5.65e-112	46	770	36	736	Protein O-mannosyl-transferase 1 OS=Mus musculus OX=10090 GN=Pomt1 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
0.999924	0.000064

TMHMM  Annotations     

Start	End
49	66
91	113
134	156
184	206
236	255
275	294
591	613
633	655
662	684
729	751