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CAZyme Information: KIW20791.1

You are here: Home > Sequence: KIW20791.1

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Exophiala spinifera
Lineage Ascomycota; Eurotiomycetes; ; Herpotrichiellaceae; Exophiala; Exophiala spinifera
CAZyme ID KIW20791.1
CAZy Family GT4
CAZyme Description Alpha-galactosidase [Source:UniProtKB/TrEMBL;Acc:A0A0D1YZP4]
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
710 KN847492|CGC23 79000.23 6.0409
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_EspiniferaCBS89968 12110 N/A 61 12049
Gene Location

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in KIW20791.1.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH27 142 398 1.6e-68 0.9781659388646288

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
269893 GH27 8.42e-122 46 333 1 271
glycosyl hydrolase family 27 (GH27). GH27 enzymes occur in eukaryotes, prokaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-N-acetylgalactosaminidase, and 3-alpha-isomalto-dextranase. All GH27 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH27 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.
239729 proteasome_beta_type_4 1.93e-98 487 688 1 197
proteasome beta type-4 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on top of one another forming an elongated alpha-beta-beta-alpha cylinder with a central cavity. The proteasome alpha and beta subunits are members of the N-terminal nucleophile (Ntn)-hydrolase superfamily. Their N-terminal threonine residues are exposed as a nucleophile in peptide bond hydrolysis.Mammals have 7 alpha and 7 beta proteasome subunits while archaea have one of each.
166449 PLN02808 2.87e-95 14 396 1 358
alpha-galactosidase
177874 PLN02229 3.54e-88 40 398 57 393
alpha-galactosidase
178295 PLN02692 1.12e-87 2 398 4 384
alpha-galactosidase

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
9.64e-185 40 411 57 427
1.47e-184 39 411 68 439
5.49e-184 40 411 57 427
7.55e-173 39 409 47 417
4.28e-172 42 398 39 395

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
3.00e-86 42 390 96 443
Crystal structure of a putative alpha-galactosidase/melibiase (BF4189) from Bacteroides fragilis NCTC 9343 at 2.00 A resolution [Bacteroides fragilis NCTC 9343],4OGZ_B Crystal structure of a putative alpha-galactosidase/melibiase (BF4189) from Bacteroides fragilis NCTC 9343 at 2.00 A resolution [Bacteroides fragilis NCTC 9343]
6.59e-86 42 393 96 446
Crystal structure of a putative alpha-galactosidase (BF1418) from Bacteroides fragilis NCTC 9343 at 1.57 A resolution [Bacteroides fragilis NCTC 9343]
5.21e-79 449 708 1 264
A Gated Channel Into The Proteasome Core Particle [Saccharomyces cerevisiae],1G0U_M A Gated Channel Into The Proteasome Core Particle [Saccharomyces cerevisiae],2ZCY_0 yeast 20S proteasome:syringolin A-complex [Saccharomyces cerevisiae],2ZCY_M yeast 20S proteasome:syringolin A-complex [Saccharomyces cerevisiae],3BDM_0 yeast 20S proteasome:glidobactin A-complex [Saccharomyces cerevisiae],3BDM_M yeast 20S proteasome:glidobactin A-complex [Saccharomyces cerevisiae],3JCO_2 Structure of yeast 26S proteasome in M1 state derived from Titan dataset [Saccharomyces cerevisiae S288C],3JCO_9 Structure of yeast 26S proteasome in M1 state derived from Titan dataset [Saccharomyces cerevisiae S288C],3JCP_2 Structure of yeast 26S proteasome in M2 state derived from Titan dataset [Saccharomyces cerevisiae S288C],3JCP_9 Structure of yeast 26S proteasome in M2 state derived from Titan dataset [Saccharomyces cerevisiae S288C],3MG6_1 Structure of yeast 20S open-gate proteasome with Compound 6 [Saccharomyces cerevisiae],3MG6_M Structure of yeast 20S open-gate proteasome with Compound 6 [Saccharomyces cerevisiae],3MG7_1 Structure of yeast 20S open-gate proteasome with Compound 8 [Saccharomyces cerevisiae],3MG7_M Structure of yeast 20S open-gate proteasome with Compound 8 [Saccharomyces cerevisiae],3MG8_1 Structure of yeast 20S open-gate proteasome with Compound 16 [Saccharomyces cerevisiae],3MG8_M Structure of yeast 20S open-gate proteasome with Compound 16 [Saccharomyces cerevisiae],3NZJ_1 Crystal structure of yeast 20S proteasome in complex with ligand 2a [Saccharomyces cerevisiae],3NZJ_M Crystal structure of yeast 20S proteasome in complex with ligand 2a [Saccharomyces cerevisiae],3NZW_1 Crystal structure of the yeast 20S proteasome in complex with 2b [Saccharomyces cerevisiae],3NZW_M Crystal structure of the yeast 20S proteasome in complex with 2b [Saccharomyces cerevisiae],3NZX_1 Crystal structure of the yeast 20S proteasome in complex with ligand 2c [Saccharomyces cerevisiae],3NZX_M Crystal structure of the yeast 20S proteasome in complex with ligand 2c [Saccharomyces cerevisiae],3WXR_2 Yeast 20S proteasome with a mutation of alpha7 subunit [Saccharomyces cerevisiae S288C],3WXR_N Yeast 20S proteasome with a mutation of alpha7 subunit [Saccharomyces cerevisiae S288C],4CR2_7 Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome [Saccharomyces cerevisiae],4CR3_7 Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome [Saccharomyces cerevisiae],4CR4_7 Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome [Saccharomyces cerevisiae],4X6Z_2 Yeast 20S proteasome in complex with PR-VI modulator [Saccharomyces cerevisiae S288C],4X6Z_N Yeast 20S proteasome in complex with PR-VI modulator [Saccharomyces cerevisiae S288C],5A5B_7 Structure of the 26S proteasome-Ubp6 complex [Saccharomyces cerevisiae],5MP9_7 26S proteasome in presence of ATP (s1) [Saccharomyces cerevisiae S288C],5MP9_n 26S proteasome in presence of ATP (s1) [Saccharomyces cerevisiae S288C],5MPA_7 26S proteasome in presence of ATP (s2) [Saccharomyces cerevisiae S288C],5MPA_n 26S proteasome in presence of ATP (s2) [Saccharomyces cerevisiae S288C],5MPB_7 26S proteasome in presence of AMP-PNP (s3) [Saccharomyces cerevisiae S288C],5MPB_n 26S proteasome in presence of AMP-PNP (s3) [Saccharomyces cerevisiae S288C],5MPC_7 26S proteasome in presence of BeFx (s4) [Saccharomyces cerevisiae S288C],5MPC_n 26S proteasome in presence of BeFx (s4) [Saccharomyces cerevisiae S288C],5NIF_2 Yeast 20S proteasome in complex with Blm-pep activator [Saccharomyces cerevisiae S288C],5NIF_N Yeast 20S proteasome in complex with Blm-pep activator [Saccharomyces cerevisiae S288C],5WVI_7 The resting state of yeast proteasome [Saccharomyces cerevisiae S288C],5WVI_a The resting state of yeast proteasome [Saccharomyces cerevisiae S288C],5WVK_7 Yeast proteasome-ADP-AlFx [Saccharomyces cerevisiae S288C],5WVK_a Yeast proteasome-ADP-AlFx [Saccharomyces cerevisiae S288C],6EF3_7 Yeast 26S proteasome bound to ubiquitinated substrate (4D motor state) [Saccharomyces cerevisiae S288C],6J2C_7 Yeast proteasome in translocation competent state (C3-a) [Saccharomyces cerevisiae S288C],6J2C_a Yeast proteasome in translocation competent state (C3-a) [Saccharomyces cerevisiae S288C],6J2N_7 yeast proteasome in substrate-processing state (C3-b) [Saccharomyces cerevisiae S288C],6J2N_a yeast proteasome in substrate-processing state (C3-b) [Saccharomyces cerevisiae S288C],6J2Q_7 Yeast proteasome in Ub-accepted state (C1-b) [Saccharomyces cerevisiae S288C],6J2Q_a Yeast proteasome in Ub-accepted state (C1-b) [Saccharomyces cerevisiae S288C],6J2X_7 Yeast proteasome in resting state (C1-a) [Saccharomyces cerevisiae S288C],6J2X_a Yeast proteasome in resting state (C1-a) [Saccharomyces cerevisiae S288C],6J30_7 yeast proteasome in Ub-engaged state (C2) [Saccharomyces cerevisiae S288C],6J30_a yeast proteasome in Ub-engaged state (C2) [Saccharomyces cerevisiae S288C],7LS5_2 Chain 2, Proteasome subunit beta type-7 [Saccharomyces cerevisiae S288C],7LS5_N Chain N, Proteasome subunit beta type-7 [Saccharomyces cerevisiae S288C],7QO3_7 Chain 7, Proteasome subunit beta type-7 [Saccharomyces cerevisiae],7QO3_n Chain n, Proteasome subunit beta type-7 [Saccharomyces cerevisiae],7QO5_7 Chain 7, Proteasome subunit beta type-7 [Saccharomyces cerevisiae],7QO5_n Chain n, Proteasome subunit beta type-7 [Saccharomyces cerevisiae],7QO6_7 Chain 7, Proteasome subunit beta [Saccharomyces cerevisiae],7QO6_n Chain n, Proteasome subunit beta [Saccharomyces cerevisiae]
4.48e-75 40 410 3 381
Crystal structure of alpha-galactosidase I from Mortierella vinacea [Umbelopsis vinacea]
1.21e-74 40 402 3 341
Chain A, alpha-galactosidase [Oryza sativa]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
7.52e-85 40 396 50 382
Alpha-galactosidase OS=Cyamopsis tetragonoloba OX=3832 PE=1 SV=1
6.13e-79 42 393 29 356
Alpha-galactosidase A OS=Cellvibrio japonicus (strain Ueda107) OX=498211 GN=agaA PE=1 SV=1
2.68e-78 449 708 1 264
Proteasome subunit beta type-7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=PRE4 PE=1 SV=1
1.96e-77 40 396 34 366
Alpha-galactosidase 2 OS=Arabidopsis thaliana OX=3702 GN=AGAL2 PE=1 SV=1
1.08e-74 454 709 8 261
Probable proteasome subunit beta type-7 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPBC577.10 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI CS Position
0.000264 0.999715 CS pos: 20-21. Pr: 0.9347

TMHMM  Annotations      help

There is no transmembrane helices in KIW20791.1.