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CAZyme Information: KIW06235.1

You are here: Home > Sequence: KIW06235.1

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Verruconis gallopava
Lineage Ascomycota; Dothideomycetes; ; Sympoventuriaceae; Verruconis; Verruconis gallopava
CAZyme ID KIW06235.1
CAZy Family GH79
CAZyme Description hypothetical protein, variant
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
762 KN847535|CGC2 84203.94 4.9929
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_VgallopavaCBS43764 9871 N/A 53 9818
Gene Location

Full Sequence      Download help

Enzyme Prediction      help

EC 2.4.1.186:3

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT8 7 223 6.1e-45 0.8793774319066148

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
133018 GT8_Glycogenin 1.13e-94 8 249 2 240
Glycogenin belongs the GT 8 family and initiates the biosynthesis of glycogen. Glycogenin initiates the biosynthesis of glycogen by incorporating glucose residues through a self-glucosylation reaction at a Tyr residue, and then acts as substrate for chain elongation by glycogen synthase and branching enzyme. It contains a conserved DxD motif and an N-terminal beta-alpha-beta Rossmann-like fold that are common to the nucleotide-binding domains of most glycosyltransferases. The DxD motif is essential for coordination of the catalytic divalent cation, most commonly Mn2+. Glycogenin can be classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. It is placed in glycosyltransferase family 8 which includes lipopolysaccharide glucose and galactose transferases and galactinol synthases.
133037 GT8_A4GalT_like 3.62e-25 8 223 4 248
A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS.
279798 Glyco_transf_8 5.24e-25 10 221 2 248
Glycosyl transferase family 8. This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase.
224359 RfaJ 7.66e-20 12 223 7 246
Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase [Cell wall/membrane/envelope biogenesis].
132996 Glyco_transf_8 2.20e-19 8 223 5 246
Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
2.82e-295 1 761 1 752
1.49e-231 1 734 1 688
2.76e-219 1 668 1 645
4.98e-206 6 720 6 727
1.88e-198 5 578 4 585

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
1.52e-44 6 246 23 273
structure of glycogenin truncated at residue 270 in a complex with UDP [Oryctolagus cuniculus],1ZCT_B structure of glycogenin truncated at residue 270 in a complex with UDP [Oryctolagus cuniculus]
1.56e-44 6 246 23 273
Structure of apo-glycogenin truncated at residue 270 [Oryctolagus cuniculus],3V8Z_A Structure of apo-glycogenin truncated at residue 270 complexed with UDP [Oryctolagus cuniculus]
2.14e-44 6 246 23 273
Structure of T82M glycogenin mutant truncated at residue 270 [Oryctolagus cuniculus],3V91_A Structure of T82M glycogenin mutant truncated at residue 270 complexed with UDP-glucose [Oryctolagus cuniculus]
4.59e-44 6 246 3 253
Crystal Structure of Rabbit Muscle Glycogenin Complexed with UDP-glucose and Manganese [Oryctolagus cuniculus],1LL3_A Crystal Structure of Rabbit Muscle Glycogenin [Oryctolagus cuniculus]
5.33e-44 6 246 9 259
Crystal Structure of Rabbit Muscle Glycogenin [Oryctolagus cuniculus],1LL0_B Crystal Structure of Rabbit Muscle Glycogenin [Oryctolagus cuniculus],1LL0_C Crystal Structure of Rabbit Muscle Glycogenin [Oryctolagus cuniculus],1LL0_D Crystal Structure of Rabbit Muscle Glycogenin [Oryctolagus cuniculus],1LL0_E Crystal Structure of Rabbit Muscle Glycogenin [Oryctolagus cuniculus],1LL0_F Crystal Structure of Rabbit Muscle Glycogenin [Oryctolagus cuniculus],1LL0_G Crystal Structure of Rabbit Muscle Glycogenin [Oryctolagus cuniculus],1LL0_H Crystal Structure of Rabbit Muscle Glycogenin [Oryctolagus cuniculus],1LL0_I Crystal Structure of Rabbit Muscle Glycogenin [Oryctolagus cuniculus],1LL0_J Crystal Structure of Rabbit Muscle Glycogenin [Oryctolagus cuniculus]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
3.59e-47 6 252 2 244
Glycogenin-1 OS=Caenorhabditis elegans OX=6239 GN=gyg-1 PE=1 SV=1
2.60e-44 6 285 3 292
Glycogenin-1 OS=Mus musculus OX=10090 GN=Gyg1 PE=1 SV=3
2.36e-43 6 246 3 253
Glycogenin-1 OS=Oryctolagus cuniculus OX=9986 GN=GYG1 PE=1 SV=3
2.36e-43 6 285 3 292
Glycogenin-1 OS=Rattus norvegicus OX=10116 GN=Gyg1 PE=2 SV=4
1.54e-41 6 246 3 253
Glycogenin-1 OS=Homo sapiens OX=9606 GN=GYG1 PE=1 SV=4

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI CS Position
1.000057 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in KIW06235.1.