CAZyme Information: KEF52902.1

Basic Information

• Species: Exophiala aquamarina
• Lineage: Ascomycota; Eurotiomycetes; ; Herpotrichiellaceae; Exophiala; Exophiala aquamarina
• CAZyme ID: KEF52902.1
• CAZy Family: AA4
• CAZyme Description: Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase [Source:UniProtKB/TrEMBL;Acc:A0A072NZQ5]

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
419		46713.23	9.5415

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_EaquamarinaCBS119918	13118	1182545	0	13118

• Gene Location: location=AMGV01000015:86540-87884(+)

Full Sequence      

MNGLLATMQDLLSNSKHTRWIGPLMILGEAMLCSLIIWKVSYTEIDWSTYMVQIQLFLDG
ERQYTKITGPTGPLVYPALHVYIYTALYHLTDEGTNILRAQTIFAGLYLVTLTVVLACYR
RVGAPPWLLVPLALSKRLHSIYVLRLFNDCWAVVGLWLAIYLLQRRKWAAGALVWGLGLG
VKMTLLLAAPGVGVVLLQGAGLAGAVWSGSSVVLSQLVLAAPFLTRDTGLDYFLRAFDFG
RQFLFKWTVNWRFVGEDTFLSKGFAIGLLVVHLALLLSFFQTKWVRPTASSLGDFVTKHF
SPLNEGEQTKISQKITPTFVMDTLLGSLVIGLLCARSLHYQFYAYLGWATPYLLWRAGGG
PVWVLLNWAIQEYSWLVFPSTDMSSGFVVMELAVQVMCALIAPPVDHIRPPVKRSVKAG

Enzyme Prediction     

EC	2.4.1.258:10

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT58	23	385	3.2e-140	0.9945054945054945

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
398745	ALG3	0.0	23	385	1	358	ALG3 protein. The formation of N-glycosidic linkages of glycoproteins involves the ordered assembly of the common Glc3Man9GlcNAc2 core-oligosaccharide on the lipid carrier dolichyl pyrophosphate. Whereas early mannosylation steps occur on the cytoplasmic side of the endoplasmic reticulum with GDP-Man as donor, the final reactions from Man5GlcNAc2-PP-Dol to Man9GlcNAc2-PP-Dol on the lumenal side use Dol-P-Man. ALG3 gene encodes the Dol-P-Man:Man5GlcNAc2-PP-Dol mannosyltransferase.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
BCR98022.1|GT58	1.83e-146	9	395	8	387
BCS10476.1|GT58	1.83e-146	9	395	8	387
BAE62911.1|GT58	2.41e-144	10	401	9	393
UDD58266.1|GT58	2.41e-144	10	401	9	393
QMW45188.1|GT58	2.38e-142	10	401	149	533

PDB Hits     

KEF52902.1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q2U6A4|ALG3_ASPOR	4.29e-145	10	401	9	393	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) OX=510516 GN=alg3 PE=3 SV=1
sp|A1CBE6|ALG3_ASPCL	1.43e-142	10	397	71	451	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) OX=344612 GN=alg3 PE=3 SV=1
sp|Q4WVG2|ALG3_ASPFU	5.22e-140	7	400	14	400	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=alg3 PE=3 SV=1
sp|Q9C1K8|ALG3_NEUCR	5.61e-140	13	396	26	415	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=alg-3 PE=3 SV=1
sp|A1DDZ3|ALG3_NEOFI	2.43e-136	7	400	6	392	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) OX=331117 GN=alg3 PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000022	0.000001

TMHMM  Annotations     

Start	End
20	42
97	119
141	163
173	195
202	224
258	280