logo
sublogo
You are browsing environment: FUNGIDB
help

CAZyme Information: KAG6624022.1

You are here: Home > Sequence: KAG6624022.1

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Phytophthora cinnamomi
Lineage Oomycota; NA; ; Peronosporaceae; Phytophthora; Phytophthora cinnamomi
CAZyme ID KAG6624022.1
CAZy Family PL3
CAZyme Description Glycosyl transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
441 46582.61 4.2399
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_PcinnamomiGKB4 19981 N/A 0 19981
Gene Location

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in KAG6624022.1.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH17 25 281 1e-21 0.9807073954983923

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
227625 Scw11 2.01e-12 26 277 47 304
Exo-beta-1,3-glucanase, GH17 family [Carbohydrate transport and metabolism].
366033 Glyco_hydro_17 4.47e-04 25 281 1 304
Glycosyl hydrolases family 17.
397323 Atrophin-1 0.004 300 400 293 378
Atrophin-1 family. Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteristic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
2.73e-102 9 285 9 288
1.23e-99 25 313 573 859
3.48e-65 26 285 29 288
7.92e-50 23 285 19 282
5.68e-43 26 197 29 200

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
9.76e-15 26 287 39 297
Crystal structure of glycoside hydrolase family 17 beta-1,3-glucanosyltransferase from Rhizomucor miehei [Rhizomucor miehei CAU432]
5.84e-14 26 287 39 297
Active-site mutant of Rhizomucor miehei beta-1,3-glucanosyltransferase in complex with laminaribiose [Rhizomucor miehei CAU432],4WTS_A Active-site mutant of Rhizomucor miehei beta-1,3-glucanosyltransferase in complex with laminaritriose [Rhizomucor miehei CAU432]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
4.69e-15 86 261 100 287
Probable glucan endo-1,3-beta-glucosidase eglC OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=eglC PE=1 SV=1
1.04e-12 86 258 100 284
Probable glucan endo-1,3-beta-glucosidase eglC OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=eglC PE=3 SV=1
1.05e-12 86 258 100 284
Probable glucan endo-1,3-beta-glucosidase eglC OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) OX=451804 GN=eglC PE=3 SV=1
1.87e-12 114 258 125 284
Probable glucan endo-1,3-beta-glucosidase eglC OS=Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) OX=331117 GN=eglC PE=3 SV=1
4.84e-12 86 258 100 284
Probable glucan endo-1,3-beta-glucosidase eglC OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) OX=341663 GN=eglC PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI CS Position
0.000252 0.999724 CS pos: 23-24. Pr: 0.9680

TMHMM  Annotations      help

There is no transmembrane helices in KAG6624022.1.