Species | Phytophthora cinnamomi | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Lineage | Oomycota; NA; ; Peronosporaceae; Phytophthora; Phytophthora cinnamomi | |||||||||||
CAZyme ID | KAG6624022.1 | |||||||||||
CAZy Family | PL3 | |||||||||||
CAZyme Description | Glycosyl transferase | |||||||||||
CAZyme Property |
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Genome Property |
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Gene Location |
Family | Start | End | Evalue | family coverage |
---|---|---|---|---|
GH17 | 25 | 281 | 1e-21 | 0.9807073954983923 |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
227625 | Scw11 | 2.01e-12 | 26 | 277 | 47 | 304 | Exo-beta-1,3-glucanase, GH17 family [Carbohydrate transport and metabolism]. |
366033 | Glyco_hydro_17 | 4.47e-04 | 25 | 281 | 1 | 304 | Glycosyl hydrolases family 17. |
397323 | Atrophin-1 | 0.004 | 300 | 400 | 293 | 378 | Atrophin-1 family. Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteristic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity. |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
2.73e-102 | 9 | 285 | 9 | 288 | |
1.23e-99 | 25 | 313 | 573 | 859 | |
3.48e-65 | 26 | 285 | 29 | 288 | |
7.92e-50 | 23 | 285 | 19 | 282 | |
5.68e-43 | 26 | 197 | 29 | 200 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
9.76e-15 | 26 | 287 | 39 | 297 | Crystal structure of glycoside hydrolase family 17 beta-1,3-glucanosyltransferase from Rhizomucor miehei [Rhizomucor miehei CAU432] |
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5.84e-14 | 26 | 287 | 39 | 297 | Active-site mutant of Rhizomucor miehei beta-1,3-glucanosyltransferase in complex with laminaribiose [Rhizomucor miehei CAU432],4WTS_A Active-site mutant of Rhizomucor miehei beta-1,3-glucanosyltransferase in complex with laminaritriose [Rhizomucor miehei CAU432] |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
4.69e-15 | 86 | 261 | 100 | 287 | Probable glucan endo-1,3-beta-glucosidase eglC OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=eglC PE=1 SV=1 |
|
1.04e-12 | 86 | 258 | 100 | 284 | Probable glucan endo-1,3-beta-glucosidase eglC OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=eglC PE=3 SV=1 |
|
1.05e-12 | 86 | 258 | 100 | 284 | Probable glucan endo-1,3-beta-glucosidase eglC OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) OX=451804 GN=eglC PE=3 SV=1 |
|
1.87e-12 | 114 | 258 | 125 | 284 | Probable glucan endo-1,3-beta-glucosidase eglC OS=Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) OX=331117 GN=eglC PE=3 SV=1 |
|
4.84e-12 | 86 | 258 | 100 | 284 | Probable glucan endo-1,3-beta-glucosidase eglC OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) OX=341663 GN=eglC PE=3 SV=1 |
Other | SP_Sec_SPI | CS Position |
---|---|---|
0.000252 | 0.999724 | CS pos: 23-24. Pr: 0.9680 |
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