CAZyme Information: KAG6623018.1

Basic Information

• Species: Phytophthora cinnamomi
• Lineage: Oomycota; NA; ; Peronosporaceae; Phytophthora; Phytophthora cinnamomi
• CAZyme ID: KAG6623018.1
• CAZy Family: PL1
• CAZyme Description: Beta-glucan synthesis-associated protein SKN1

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
597	JAFJYM010000003|CGC1	66084.54	5.0939

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_PcinnamomiGKB4	19981	N/A	0	19981

• Gene Location: location=JAFJYM010000003:122080-136673(-)

Full Sequence      

MGKNNTLSGRTFPTKSGIKPWVDPDTPTDRRTYTSSRGRQWDLVMSDEFNVANRSFRPGD
DHMWTSLEKPDGVNGALELYSHNMTSTKCDDDGTCYFYIKSVDEVNVIHVYNMYTHPPGF
TDANFFYRSAMVQSWNKFCYQGGMLEVRAQLPGAVSKASGNPDLALGKSGKVATSNYYPT
WPGIWMMGNLGRAIFSASTNRMWPFSYNKCDPDVFNSSNQRISACDANPGYGLNPNQGRG
APEIDVLEGGGLAISSSLQIAPGMPDDYRLISANTSTGDYYSCFYSYGCQTPGANNIDVP
TAYYQRQRGHKSWYQGLRYASNNECMQSSSLKQSYNTIASSMKAGITENSCSLQTCPASF
DVHTDVSLIDGTENDHWGINSNGTCFPVINSYMGAYLCDPDNTNSKCASPRSSSTPKSSA
MSPFNYQMDAISSNWPIHLGAYVDFVVYQLEWVTGKKGYNAGKTNPEKLMLEEPMYVIFN
VALSATWGAKPPNPGQECRGDGKDEAVNKICDSFPMFMKVDYIRLYQDHGDGLDADNYMQ
VGMGADTDAIETETFGEHHTTAKAMRVAYQLDVCKSDKDNIVLIMDYAQNLAGTFYP

Enzyme Prediction     

EC	-	-

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH16	47	273	2e-64	0.6134969325153374

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
397841	SKN1	5.86e-56	11	277	86	332	Beta-glucan synthesis-associated protein (SKN1). This family consists of the beta-glucan synthesis-associated proteins KRE6 and SKN1. Beta1,6-Glucan is a key component of the yeast cell wall, interconnecting cell wall proteins, beta1,3-glucan, and chitin. It has been postulated that the synthesis of beta1,6-glucan begins in the endoplasmic reticulum with the formation of protein-bound primer structures and that these primer structures are extended in the Golgi complex by two putative glucosyltransferases that are functionally redundant, Kre6 and Skn1. This is followed by maturation steps at the cell surface and by coupling to other cell wall macromolecules.
185689	GH16_fungal_KRE6_glucanase	1.87e-43	43	527	1	295	Saccharomyces cerevisiae KRE6 and related glucanses, member of glycosyl hydrolase family 16. KRE6 is a Saccharomyces cerevisiae glucanase that participates in the synthesis of beta-1,6-glucan, a major structural component of the cell wall. It is a golgi membrane protein required for normal beta-1,6-glucan levels in the cell wall. KRE6 is closely realted to laminarinase, a glycosyl hydrolase family 16 member that hydrolyzes 1,3-beta-D-glucosidic linkages in 1,3-beta-D-glucans such as laminarins, curdlans, paramylons, and pachymans, with very limited action on mixed-link (1,3-1,4-)-beta-D-glucans.
225182	BglS	2.31e-09	22	410	30	353	Beta-glucanase, GH16 family [Carbohydrate transport and metabolism].
185693	GH16_laminarinase_like	3.25e-05	444	526	159	235	Laminarinase, member of the glycosyl hydrolase family 16. Laminarinase, also known as glucan endo-1,3-beta-D-glucosidase, is a glycosyl hydrolase family 16 member that hydrolyzes 1,3-beta-D-glucosidic linkages in 1,3-beta-D-glucans such as laminarins, curdlans, paramylons, and pachymans, with very limited action on mixed-link (1,3-1,4-)-beta-D-glucans.
185693	GH16_laminarinase_like	3.87e-05	46	189	2	103	Laminarinase, member of the glycosyl hydrolase family 16. Laminarinase, also known as glucan endo-1,3-beta-D-glucosidase, is a glycosyl hydrolase family 16 member that hydrolyzes 1,3-beta-D-glucosidic linkages in 1,3-beta-D-glucans such as laminarins, curdlans, paramylons, and pachymans, with very limited action on mixed-link (1,3-1,4-)-beta-D-glucans.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
UIZ28149.1|GH16	9.05e-304	7	542	24	581
UIZ27810.1|GH16	2.25e-297	2	542	56	620
UIZ28151.1|GH16	7.74e-293	8	542	26	584
UIZ28152.1|GH16	4.29e-291	1	542	7	569
UIZ28150.1|GH16	1.01e-252	45	542	1	519

PDB Hits     

KAG6623018.1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P33336|SKN1_YEAST	1.32e-34	4	262	340	574	Beta-glucan synthesis-associated protein SKN1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=SKN1 PE=1 SV=1
sp|P32486|KRE6_YEAST	1.98e-34	7	262	291	522	Beta-glucan synthesis-associated protein KRE6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=KRE6 PE=1 SV=2
sp|P87024|SKN1_CANAX	3.98e-33	7	262	320	549	Beta-glucan synthesis-associated protein SKN1 OS=Candida albicans OX=5476 GN=SKN1 PE=2 SV=1
sp|P87023|KRE6_CANAX	5.67e-31	7	278	316	579	Beta-glucan synthesis-associated protein KRE6 OS=Candida albicans OX=5476 GN=KRE6 PE=2 SV=1
sp|O13941|YEPB_SCHPO	2.32e-26	22	249	219	415	Uncharacterized beta-glucan synthesis-associated protein C23H3.11c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPAC23H3.11c PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000081	0.000000

TMHMM  Annotations     

There is no transmembrane helices in KAG6623018.1.