You are browsing environment: FUNGIDB
CAZyme Information: KAG5419324.1
You are here: Home > Sequence: KAG5419324.1
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Candida metapsilosis | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Ascomycota; Saccharomycetes; ; Debaryomycetaceae; Candida; Candida metapsilosis | |||||||||||
| CAZyme ID | KAG5419324.1 | |||||||||||
| CAZy Family | GH72 | |||||||||||
| CAZyme Description | DED1 | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 672801; End:676423 Strand: + | |||||||||||
Full Sequence Download help
| MSDISQQMNN LSVQENGSNG QYQPRQNGRR QYVPPHLRGR SGQQQQSNGG SDDIPFGGSR | 60 |
| RNGYDNRGGF SSRGNGFGFG GGSRGGARGG GAGFGGGRYQ RQVPGVGKWV DGKHVPAPRN | 120 |
| ERLELELFGV PEEEGTHLSG INFDNYDDIP VEASGDNVPE PITAFTSPPL DELLVENIKL | 180 |
| SNFTKPTPVQ KYSVPIVAGG RDLMACAQTG SGKTGGFLFP VLSESYANGP APVPESTGTF | 240 |
| SSHKAYPTAL VMAPTRELVS QIYDESKKFA YRSWVRPCVV YGGADIGNQI RQLDRGCDLL | 300 |
| VATPGRLKDL LERGRVSLAN IKYLVLDEAD RMLDMGFEPQ IRQIVQECDM PSVENRQTLM | 360 |
| FSATFPRDIQ MLARDFLKNY IFLSVGRVGS TSENITQRVL YVEDEEKKSV ILDMLNANSS | 420 |
| GLTIVFTETK RMADNLADFL YDQGFPATAI HGDRSQYERE KALAAFKSGK APILVATAVA | 480 |
| ARGLDIPNVS HVINYDLPGD IDDYVHRIGR TGRAGNVGIA TAFFNRNNKN IAKEMIDLLS | 540 |
| EANQEVPDFL TKISRESAFG RGGRGSSRGG GYGGRGGATR DFRRSGGGGH SNSGWGSSAG | 600 |
| SGWGNSGNSG WGNSNGSSGG YGSGSGSGSR SNFNSSYGNP SGNTSWCSTD ILYFSTKRHS | 660 |
| LDRGMGRRNF KTALVTTVLL LVVYLLYSSY DGHGSYKTEP NSNKLQLLRE LEANKEWKTK | 720 |
| GFNFQPRLKP IPDQSSITLQ QLYQSIPYDS TSAFPKFIWQ TWKVDLKDES FPKRYRHYQA | 780 |
| TWDDKNPSYK HFVIPDEQCD TLVEELYSEV PDVAKAYKNM PKSILKADFF RYLILFARGG | 840 |
| VYTDIDTVGL KPIDEWAGSN EEIAGKANNA GLVVGIEADP DRPDWAEWYA RRIQFCQWTI | 900 |
| QSKRGHPMLA QLIAKITDIT LTRLEKGQLR TVLGKNEGGD VMNWTGPGIF TDYVFKYLNQ | 960 |
| IVEVDWRLFT GMEQPILIDD VLVLPITSFS PDVNQMGAKS SSHPMAFAKH MFSGSWKDDG | 1020 |
| MPAMGS | 1026 |
Enzyme Prediction help
| EC | 2.4.1.257:12 |
|---|
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT32 | 774 | 857 | 3.7e-21 | 0.9444444444444444 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| 350809 | DEADc_DDX3 | 2.46e-155 | 143 | 390 | 1 | 249 | DEAD-box helicase domain of DEAD box protein 3. DDX3 (also called helicase-like protein, DEAD box, X isoform, or DDX14) has been reported to display a high level of RNA-independent ATPase activity stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. Diseases associated with DDX3 include mental retardation, X-linked 102 and agenesis of the corpus callosum, with facial anomalies and robin sequence. DDX3 is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region. |
| 350725 | DEADc_DDX3_DDX4 | 9.40e-155 | 165 | 389 | 2 | 221 | DEAD-box helicase domain of ATP-dependent RNA helicases DDX3 and DDX4. This subfamily includes Drosophila melanogaster Vasa, which is essential for development. DEAD box protein 3 (DDX3) has been reported to display a high level of RNA-independent ATPase activity stimulated by both RNA and DNA. DEAD box protein 4 (DDX4, also known as VASA homolog) is an ATP-dependent RNA helicase required during spermatogenesis and is essential for the germline integrity. DDX3 and DDX4 are members of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region. |
| 223587 | SrmB | 1.87e-143 | 142 | 558 | 8 | 415 | Superfamily II DNA and RNA helicase [Replication, recombination and repair]. |
| 350810 | DEADc_DDX4 | 1.67e-136 | 116 | 389 | 5 | 264 | DEAD-box helicase domain of DEAD box protein 4. DEAD box protein 4 (DDX4, also known as VASA homolog) is an ATP-dependent RNA helicase required during spermatogenesis and is essential for the germline integrity. DEAD-box helicases are a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region. |
| 240273 | PTZ00110 | 1.59e-123 | 155 | 557 | 122 | 514 | helicase; Provisional |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| CCG25808.1|GT32 | 3.56e-239 | 665 | 1026 | 1 | 362 |
| CCE44689.1|GT32 | 5.21e-228 | 665 | 1024 | 1 | 360 |
| CAX43101.1|GT32 | 1.06e-179 | 665 | 1024 | 9 | 383 |
| AOW28617.1|GT32 | 4.37e-179 | 665 | 1024 | 9 | 383 |
| AAL49987.1|GT32|2.4.1.257 | 4.37e-179 | 665 | 1024 | 9 | 383 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6O5F_A | 1.13e-190 | 116 | 587 | 8 | 476 | Crystal structure of DEAD-box RNA helicase DDX3X at pre-unwound state [Homo sapiens],6O5F_B Crystal structure of DEAD-box RNA helicase DDX3X at pre-unwound state [Homo sapiens] |
| 6CZ5_A | 7.28e-190 | 116 | 587 | 12 | 480 | Crystal structure of small molecule AMP-acrylamide covalently bound to DDX3 S228C [Homo sapiens] |
| 5E7I_A | 6.04e-189 | 116 | 559 | 7 | 448 | Crystal structure of the active catalytic core of the human DEAD-box protein DDX3 [Homo sapiens],5E7I_B Crystal structure of the active catalytic core of the human DEAD-box protein DDX3 [Homo sapiens],5E7I_C Crystal structure of the active catalytic core of the human DEAD-box protein DDX3 [Homo sapiens],5E7J_A Crystal structure of the active catalytic core of the human DEAD-box protein DDX3 bound to AMP [Homo sapiens],5E7M_A Crystal structure of the active catalytic core of the human DEAD-box protein DDX3 bound to AMPPNP [Homo sapiens] |
| 4PXA_A | 2.29e-187 | 116 | 559 | 24 | 465 | DEAD-box RNA helicase DDX3X Cancer-associated mutant D354V [Homo sapiens] |
| 2I4I_A | 4.18e-178 | 151 | 559 | 3 | 415 | Crystal Structure of human DEAD-box RNA helicase DDX3X [Homo sapiens] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| sp|A5DZE6|DED1_LODEL | 0.0 | 1 | 593 | 1 | 609 | ATP-dependent RNA helicase DED1 OS=Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) OX=379508 GN=DED1 PE=3 SV=1 |
| sp|Q5A4E2|DED1_CANAL | 9.94e-309 | 1 | 592 | 1 | 612 | ATP-dependent RNA helicase DED1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=DED1 PE=3 SV=1 |
| sp|A5DQS0|DED1_PICGU | 1.10e-303 | 1 | 588 | 1 | 600 | ATP-dependent RNA helicase DED1 OS=Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) OX=294746 GN=DED1 PE=3 SV=3 |
| sp|Q6BU54|DED1_DEBHA | 6.90e-303 | 1 | 646 | 1 | 629 | ATP-dependent RNA helicase DED1 OS=Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) OX=284592 GN=DED1 PE=3 SV=1 |
| sp|A3LQ01|DED1_PICST | 1.66e-295 | 1 | 560 | 1 | 565 | ATP-dependent RNA helicase DED1 OS=Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) OX=322104 GN=DED1 PE=3 SV=3 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | CS Position |
|---|---|---|
| 1.000068 | 0.000000 |