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CAZyme Information: KAG5418105.1
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Candida metapsilosis | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Ascomycota; Saccharomycetes; ; Debaryomycetaceae; Candida; Candida metapsilosis | |||||||||||
| CAZyme ID | KAG5418105.1 | |||||||||||
| CAZy Family | GH17 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | ||||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH16 | 2325 | 2495 | 3.9e-77 | 0.9827586206896551 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| 215595 | PLN03130 | 0.0 | 138 | 1384 | 157 | 1465 | ABC transporter C family member; Provisional |
| 215640 | PLN03232 | 0.0 | 138 | 1403 | 157 | 1480 | ABC transporter C family member; Provisional |
| 188098 | MRP_assoc_pro | 0.0 | 255 | 1382 | 301 | 1510 | multi drug resistance-associated protein (MRP). This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other] |
| 240327 | PTZ00243 | 4.84e-179 | 292 | 1385 | 265 | 1538 | ABC transporter; Provisional |
| 185765 | BRO1_ScBro1_like | 2.69e-138 | 1386 | 1759 | 7 | 348 | Protein-interacting, N-terminal, Bro1-like domain of Saccharomyces cerevisiae Bro1 and related proteins. This family contains the N-terminal, Bro1-like domain of Saccharomyces cerevisiae Bro1 and related proteins. It belongs to the BRO1_Alix_like superfamily which also includes the Bro1-like domains of mammalian Alix (apoptosis-linked gene-2 interacting protein X), His-Domain type N23 protein tyrosine phosphatase (HD-PTP, also known as PTPN23), RhoA-binding proteins Rhophilin-1 and -2, Brox, Saccharomyces cerevisiae Rim20 (also known as PalA), Ustilago maydis Rim23 (also known as PalC), and related domains. Alix, HD-PTP, Brox, Bro1, Rim20, and Rim23, interact with the ESCRT (Endosomal Sorting Complexes Required for Transport) system. Bro1 participates in endosomal trafficking. Bro1-like domains are boomerang-shaped, and part of the domain is a tetratricopeptide repeat (TPR)-like structure. Bro1-like domains bind components of the ESCRT-III complex: Snf7 in the case of Bro1. Snf7 binds to a conserved hydrophobic patch on the middle of the concave side of the Bro1 domain. RIM20, and some other members of the BRO1_Alix_like superfamily including Alix, also have a V-shaped (V) domain. In the case of Alix, the V-domain contains a binding site for the retroviral late assembly (L) domain YPXnL motif, which is partially conserved in the superfamily. The Alix V-domain is also a dimerization domain. The C-terminal portion (V-domain and proline rich-region) of Bro1 interacts with Doa4, a protease that deubiquitinates integral membrane proteins sorted into the lumenal vesicles of late-endosomal multivesicular bodies. It interacts with a YPxL motif in the Doa4 catalytic domain to stimulate its deubiquitination activity. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| 0.0 | 6 | 2574 | 27 | 2789 | |
| 3.25e-261 | 2236 | 2683 | 14 | 461 | |
| 1.79e-257 | 2236 | 2683 | 14 | 461 | |
| 5.18e-203 | 2236 | 2682 | 20 | 469 | |
| 2.23e-189 | 2236 | 2682 | 21 | 480 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 1.31e-266 | 109 | 1385 | 114 | 1501 | Chain A, Metal resistance protein YCF1 [Saccharomyces cerevisiae] |
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| 1.24e-265 | 109 | 1385 | 137 | 1524 | Chain A, Metal resistance protein YCF1 [Saccharomyces cerevisiae S288C],7M69_A Chain A, Metal resistance protein YCF1 [Saccharomyces cerevisiae S288C] |
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| 1.06e-208 | 293 | 1382 | 266 | 1438 | Cryo-EM structure of bovine multidrug resistance protein 1 (MRP1) [Bos taurus],5UJA_A Cryo-EM structure of bovine multidrug resistance protein 1 (MRP1) bound to leukotriene C4 [Bos taurus] |
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| 7.24e-208 | 293 | 1382 | 345 | 1517 | Cryo-EM structure of wild-type bovine multidrug resistance protein 1 (MRP1) under active turnover conditions [Bos taurus] |
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| 2.96e-206 | 293 | 1382 | 465 | 1637 | Cryo-EM structure of ATP-bound, outward-facing bovine multidrug resistance protein 1 (MRP1) [Bos taurus] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 1.09e-311 | 6 | 1385 | 53 | 1594 | Multiple drug resistance-associated protein-like transporter 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=MLT1 PE=1 SV=1 |
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| 1.61e-279 | 9 | 1385 | 16 | 1547 | Bile pigment transporter 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=BPT1 PE=1 SV=2 |
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| 3.65e-266 | 109 | 1385 | 114 | 1501 | Metal resistance protein YCF1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=YCF1 PE=1 SV=2 |
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| 4.82e-264 | 115 | 1385 | 104 | 1467 | ATP-binding cassette transporter abc2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=abc2 PE=1 SV=1 |
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| 1.54e-249 | 125 | 1385 | 96 | 1454 | Vacuolar heme ABC transmembrane exporter abc3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=abc3 PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | CS Position |
|---|---|---|
| 1.000023 | 0.000001 |
TMHMM Annotations download full data without filtering help
| Start | End |
|---|---|
| 26 | 48 |
| 69 | 91 |
| 96 | 118 |
| 125 | 147 |
| 162 | 184 |
| 262 | 284 |
| 307 | 329 |
| 388 | 410 |
| 415 | 437 |
| 494 | 516 |
| 869 | 891 |
| 911 | 933 |
| 983 | 1005 |
| 1059 | 1081 |