CAZyme Information: KAG5295899.1

Basic Information

• Species: Histoplasma capsulatum
• Lineage: Ascomycota; Eurotiomycetes; ; Ajellomycetaceae; Histoplasma; Histoplasma capsulatum
• CAZyme ID: KAG5295899.1
• CAZy Family: GH3
• CAZyme Description: glycosyl hydrolase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
448	JAEVHI010000003|CGC7	50494.96	8.9418

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_HcapsulatumG184AR	12723	N/A	3308	9415

• Gene Location: location=JAEVHI010000003:1499065-1500519(-)

Full Sequence      

MQVQAYPSRLPSPAGSRQSMSIISTFLHLLLLALPIHGIDVDLDNDDSVAMTARVLAAGV
RHYYTGDRPGGVPGYLPPPYYWWEAGAMFGSLIDYWFYTGDSTYNNIIIQAMLHQASDTQ
NFMPANQTRVEANDDQCFWALAAMAAAERRFTDPPPDQPQWLTLVQGTFNSQAARWDMET
CGGGLKWQIFRFNKGFNYKNTISNGCFFNIAARLATYTNNHTYAAWAEKTWEWVQRIGLI
TPDYYFLDGTDDLKNCSQLNRNRWTYNAGIFMLGAAHMYQFVSVKSHLIFFSSNPSAIYC
LEKARANLPLAPPNRPTENPPAKHHQRPPHLHPQRLQRPLRTHLRSPQQMHNRPALLQSL
PRALDGRHDANLPLHDGAAPADPARLCRRRRQRLHHRHQRRAVLTEVECRPLRGQRRAGA
ADGGARGDSGAAGPARAAACVGEDEQDE

Enzyme Prediction     

EC	3.2.1.101:2

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH76	51	283	2.1e-74	0.6145251396648045

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
397638	Glyco_hydro_76	5.58e-127	48	281	1	234	Glycosyl hydrolase family 76. Family of alpha-1,6-mannanases.
227170	COG4833	2.45e-08	182	272	133	215	Predicted alpha-1,6-mannanase, GH76 family [Carbohydrate transport and metabolism].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QSS73882.1|GH76	0.0	1	448	1	448
QSS66977.1|GH76	2.86e-210	1	283	1	283
QSS56044.1|GH76	2.68e-207	1	283	46	328
QGA21543.1|GH76	4.43e-118	17	298	6	296
QMS79050.1|GH76	1.29e-115	28	280	6	259

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6RY0_A	4.83e-74	43	281	30	277	Chain A, Mannan endo-1,6-alpha-mannosidase [Thermochaetoides thermophila DSM 1495],6RY1_A Chain A, Mannan endo-1,6-alpha-mannosidase [Thermochaetoides thermophila DSM 1495],6RY2_A Chain A, Mannan endo-1,6-alpha-mannosidase [Thermochaetoides thermophila DSM 1495],6RY5_A Chain A, Mannan endo-1,6-alpha-mannosidase [Thermochaetoides thermophila DSM 1495],6RY6_A Chain A, Mannan endo-1,6-alpha-mannosidase [Thermochaetoides thermophila DSM 1495],6RY7_A Chain A, Mannan endo-1,6-alpha-mannosidase [Thermochaetoides thermophila DSM 1495]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P36091|DCW1_YEAST	4.95e-89	37	281	20	266	Mannan endo-1,6-alpha-mannosidase DCW1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=DCW1 PE=1 SV=1
sp|Q75DG6|DCW1_ASHGO	1.47e-88	29	280	12	267	Mannan endo-1,6-alpha-mannosidase DCW1 OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) OX=284811 GN=DCW1 PE=3 SV=2
sp|O74556|YCZ2_SCHPO	5.53e-86	38	283	19	264	Putative mannan endo-1,6-alpha-mannosidase C970.02 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPCC970.02 PE=3 SV=1
sp|Q6FLP9|DCW1_CANGA	1.23e-85	25	280	5	262	Mannan endo-1,6-alpha-mannosidase DCW1 OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) OX=284593 GN=DCW1 PE=3 SV=1
sp|Q5AD78|DCW1_CANAL	8.97e-84	24	281	4	263	Mannan endo-1,6-alpha-mannosidase DCW1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=DCW1 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.003565	0.996380	CS pos: 38-39. Pr: 0.9415

TMHMM  Annotations     

There is no transmembrane helices in KAG5295899.1.