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CAZyme Information: KAG4306253.1

You are here: Home > Sequence: KAG4306253.1

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Pneumocystis oryctolagi
Lineage Ascomycota; Pneumocystidomycetes; ; Pneumocystidaceae; Pneumocystis; Pneumocystis oryctolagi
CAZyme ID KAG4306253.1
CAZy Family GT50
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1588 JABTEG010000001|CGC3 181343.29 9.0601
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_PoryctolagiCS1 2856 N/A 0 2856
Gene Location Start: 905787; End:911519  Strand: -

Full Sequence      Download help

MTVAPLRIVK  KHNSNASPPL  LPQPIHEILQ  DLSLSTQKEN  TNISHDFTYC  RVIYAFSIEQ60
SDASYLKLER  DQIIHVHFQH  FSGWTDGTLI  ATNSRGWFPL  KYTEPYILMA  VRPVVAASHG120
LYALFSSHKY  EEYAIGISNL  IFGVRQLLIR  ANSLSHEALV  VKNDPAIRQK  RKTLLSELDN180
LVSITKNVSK  QSSNHTINAK  LSNELIFLLG  RIVLLSKQFA  HMIGPEKEAC  DEPLSSPTLS240
LNSEFSENIY  MHHRIASVDS  SSFASLDEQT  DKIYSGSLDS  HQSSKSSLNS  QTYCNPVNIL300
HNLTVANEDF  LSHLASFIGR  LHLHSHTSSQ  LLLTTKQCVY  TARELLSVIE  PVSIKHPDAQ360
LYIAKENFYT  KITSFVAIVK  KVITTHCSTN  TSNEQNTIDK  SESKKLIDAA  ANCVSGASQC420
VTRAKFILET  IGGSSISTPL  YKQGNFSQST  SVNTLSSKSS  QTTFENTSPQ  EAYKSYNTFL480
TSPPLKLSSN  IHEAEKKGVL  NEYSISSKNT  SQEPINNKDN  SSYLNDNADL  NTKQILNKCR540
KGSSELSHGL  LIKPPTLFST  CSSSTSECNE  KAMLDSKLKT  HHDLPSGTAS  SFASSERFSI600
TSSYVEHISS  PATSPEPVEL  DTISRNKEEK  KNSKHILLNN  EGQVIGATLY  ALVERMTMHD660
TTPDAVFAST  FYLTFRLFTT  PRELALVLLE  RFPTEKTVDA  DHNWDHYYAM  PVRLRTWMDN720
YWHKSSDEEA  LSIIRDFSCQ  LHKYLPQVSS  RFDELVNKIS  SKTSQNTHST  NISRKVYNLS780
NKSMHSDLSI  PPVIISKNLR  TQLRTASFED  NPDSFSIIDF  DPLEIARQLT  LKESKLFCSI840
LPEELVKLGT  SRKANASTTV  KAMAALSTDI  AGWVVESILS  QNDIKKRAAV  MKQWIKIGNK900
CLELSNYNTL  MAIVSALNSS  TISRLKKTWN  ALSTKSKNIF  ENLRSITDYS  RNYAVYRSRL960
KEHFPPCLPF  LGLILTDITF  IEEGNPSYRS  FKNSSALHPI  QLINYDKYIK  IYSIISKLQQ1020
FQVPYKLEFV  EGLQTWIESQ  ISCVRMKGQN  NVTELWRRSL  ALEPKIQSQS  SQQNDQTKNS1080
TDNSILTVSE  MVEDSDAKKH  CYNIFSEEYV  TPVSIFIQIM  ILGPLCIYIL  IKTYKKLYTK1140
SKKIRSFFHP  YCNSGGGGER  VLWTAIKAIQ  DKYNNIICVI  YTGDVNSKKE  DILTKTKTIF1200
DIELDEKRTQ  FIYLYKRYYI  SSEQWPRFTL  LGQSLGSLIL  AYEAINQCVP  NIFIDTMGYA1260
FTYPLISFCL  DIPIVAYVHY  PTISTDMLSK  VPYRRIFKYI  YWKFFSFIYS  FCGHYAHLVI1320
TNSSWTQNHM  ESLWKKKKEI  LTIYPPCNTK  DLYNSNINNN  KREKLIVYLA  QFRKEKNHIL1380
LLKSFKTMLD  TYPETKNYGI  KMVLIGSTRE  DDELYIDSLK  SMIKSLNISS  YVLFAHNLPW1440
NEVVEWLRKS  WIGVNTMWNE  HFGISIVEYM  AAELIPVVHD  SGGPKLDIVI  DYEGKPTGAN1500
KKYTIMHTLI  VYLGYRATTP  SSFAKAFKDI  FSMSQEECNF  MRKRARMSST  RFSEEKFQES1560
WLNIMNILLK  YEKAYRHKRI  DRTKFKEY1588

Enzyme Prediction      help

EC 2.4.1.131:1

CAZyme Signature Domains help

Created with Snap7915823831739747655563571479487395210321111119112701349142915084124GT4
Family Start End Evalue family coverage
GT4 1358 1489 6.7e-27 0.75

CDD Domains      download full data without filtering help

Created with Snap79158238317397476555635714794873952103211111191127013491429150811471560GT4_ALG11-like11471569PLN0294911471334ALG11_N8241008RasGEF8171066RasGEF
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
340835 GT4_ALG11-like 0.0 1147 1560 5 419
alpha-1,2-mannosyltransferase ALG11 and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. ALG11 in yeast is involved in adding the final 1,2-linked Man to the Man5GlcNAc2-PP-Dol synthesized on the cytosolic face of the ER. The deletion analysis of ALG11 was shown to block the early steps of core biosynthesis that takes place on the cytoplasmic face of the ER and lead to a defect in the assembly of lipid-linked oligosaccharides.
215511 PLN02949 4.41e-124 1147 1569 38 458
transferase, transferring glycosyl groups
406369 ALG11_N 1.12e-114 1147 1334 5 208
ALG11 mannosyltransferase N-terminus.
395492 RasGEF 1.22e-69 824 1008 1 178
RasGEF domain. Guanine nucleotide exchange factor for Ras-like small GTPases.
214539 RasGEF 6.10e-63 817 1066 1 242
Guanine nucleotide exchange factor for Ras-like small GTPases.

CAZyme Hits      help

Created with Snap79158238317397476555635714794873952103211111191127013491429150811031588QSL65024.1|GT411341570CAA20913.1|GT4|2.4.1.13111341570NP_587708.1|GT4|2.4.1.13111441569EGX46298.1|GT411471562AIT18233.1|GT4
Hit ID E-Value Query Start Query End Hit Start Hit End
QSL65024.1|GT4 1.07e-238 1103 1588 13 508
CAA20913.1|GT4|2.4.1.131 2.08e-122 1134 1570 44 465
NP_587708.1|GT4|2.4.1.131 2.08e-122 1134 1570 44 465
EGX46298.1|GT4 8.37e-122 1144 1569 91 526
AIT18233.1|GT4 9.10e-118 1147 1562 60 474

PDB Hits      download full data without filtering help

Created with Snap79158238317397476555635714794873952103211111191127013491429150864810651BKD_S64810651NVU_S64810655WFO_N64810651XD2_C64810654URU_S
Hit ID E-Value Query Start Query End Hit Start Hit End Description
1BKD_S 8.61e-35 648 1065 38 452
Complex Of Human H-Ras With Human Sos-1 [Homo sapiens]
1NVU_S 9.17e-35 648 1065 40 454
Chain S, Son of sevenless protein homolog 1 [Homo sapiens],1NVV_S Chain S, Son of sevenless protein homolog 1 [Homo sapiens],1NVW_S Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS [Homo sapiens],1NVX_S Chain S, Son of sevenless protein homolog 1 [Homo sapiens],4NYI_S Approach for Targeting Ras with Small Molecules that Activate SOS-Mediated Nucleotide Exchange [Homo sapiens],4NYJ_S Approach for Targeting Ras with Small Molecules that Activate SOS-Mediated Nucleotide Exchange [Homo sapiens],4NYM_S Approach for Targeting Ras with Small Molecules that Activate SOS-Mediated Nucleotide Exchange [Homo sapiens]
5WFO_N 9.32e-35 648 1065 41 455
Ligand-bound Ras:SOS:Ras complex [Homo sapiens],5WFP_N Ligand-bound Ras:SOS:Ras complex [Homo sapiens],5WFQ_N Ligand-bound Ras:SOS:Ras complex [Homo sapiens],5WFR_N Ligand-bound Ras:SOS:Ras complex [Homo sapiens],6BVI_B Ras:SOS:Ras in complex with a small molecule activator [Homo sapiens],6BVJ_B Ras:SOS:Ras in complex with a small molecule activator [Homo sapiens],6BVK_B Ras:SOS:Ras in complex with a small molecule activator [Homo sapiens],6BVL_B Ras:SOS:Ras in complex with a small molecule activator [Homo sapiens],6BVM_B Ras:SOS:Ras in complex with a small molecule activator [Homo sapiens],6CUO_B Ras:SOS:Ras in complex with a small molecule activator [Homo sapiens],6CUP_B Ras:SOS:Ras in complex with a small molecule activator [Homo sapiens],6CUR_B Ras:SOS:Ras in complex with a small molecule activator [Homo sapiens],6D55_B Ras:SOS:Ras in complex with a small molecule activator [Homo sapiens],6D56_B Ras:SOS:Ras in complex with a small molecule activator [Homo sapiens],6D59_B Ras:SOS:Ras in complex with a small molecule activator [Homo sapiens],6D5E_B Ras:SOS:Ras in complex with a small molecule activator [Homo sapiens],6D5G_B Ras:SOS:Ras in complex with a small molecule activator [Homo sapiens],6D5H_B Ras:SOS:Ras in complex with a small molecule activator [Homo sapiens],6D5J_B Ras:SOS:Ras in complex with a small molecule activator [Homo sapiens],6D5L_B Ras:SOS:Ras in complex with a small molecule activator [Homo sapiens],6D5M_S Ras:SOS:Ras in complex with a small molecule activator [Homo sapiens],6D5V_S Ras:SOS:Ras in complex with a small molecule activator [Homo sapiens],6D5W_S Ras:SOS:Ras in complex with a small molecule activator [Homo sapiens],6V94_B Expanding the Chemical Landscape of SOS1 Activators Using Fragment Based Methods [Homo sapiens],6V9F_B Expanding the Chemical Landscape of SOS1 Activators Using Fragment Based Methods [Homo sapiens],6V9J_B Expanding the Chemical Landscape of SOS1 Activators Using Fragment Based Methods [Homo sapiens],6V9L_B Expanding the Chemical Landscape of SOS1 Activators Using Fragment Based Methods [Homo sapiens],6V9M_B Expanding the Chemical Landscape of SOS1 Activators Using Fragment Based Methods [Homo sapiens],6V9N_B Expanding the Chemical Landscape of SOS1 Activators Using Fragment Based Methods [Homo sapiens],6V9O_B Expanding the Chemical Landscape of SOS1 Activators Using Fragment Based Methods [Homo sapiens]
1XD2_C 9.62e-35 648 1065 40 454
Chain C, Son of sevenless protein homolog 1 [Homo sapiens]
4URU_S 1.01e-34 648 1065 43 457
The crystal structure of H-Ras and SOS in complex with ligands [Homo sapiens],4URV_S The crystal structure of H-Ras and SOS in complex with ligands [Homo sapiens],4URW_S The crystal structure of H-Ras and SOS in complex with ligands [Homo sapiens],4URX_S The crystal structure of H-Ras and SOS in complex with ligands [Homo sapiens],4URY_S The crystal structure of H-Ras and SOS in complex with ligands [Homo sapiens],4URZ_S The crystal structure of H-Ras and SOS in complex with ligands [Homo sapiens],4US0_S The crystal structure of H-Ras and SOS in complex with ligands [Homo sapiens],4US1_S The crystal structure of H-Ras and SOS in complex with ligands [Homo sapiens],4US2_S The crystal structure of H-Ras and SOS in complex with ligands [Homo sapiens]

Swiss-Prot Hits      download full data without filtering help

Created with Snap79158238317397476555635714794873952103211111191127013491429150811341570sp|O74878|ALG11_SCHPO11191570sp|Q2TAA5|ALG11_HUMAN11191570sp|Q5R7Z6|ALG11_PONAB11361562sp|Q8X092|ALG11_NEUCR11191569sp|Q3TZM9|ALG11_MOUSE
Hit ID E-Value Query Start Query End Hit Start Hit End Description
sp|O74878|ALG11_SCHPO 3.70e-123 1134 1570 44 465
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=alg11 PE=3 SV=1
sp|Q2TAA5|ALG11_HUMAN 4.55e-105 1119 1570 25 492
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase OS=Homo sapiens OX=9606 GN=ALG11 PE=1 SV=2
sp|Q5R7Z6|ALG11_PONAB 1.61e-104 1119 1570 25 492
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase OS=Pongo abelii OX=9601 GN=ALG11 PE=2 SV=2
sp|Q8X092|ALG11_NEUCR 2.04e-103 1136 1562 92 537
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=alg-11 PE=3 SV=1
sp|Q3TZM9|ALG11_MOUSE 2.77e-103 1119 1569 25 491
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase OS=Mus musculus OX=10090 GN=Alg11 PE=2 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI CS Position
1.000074 0.000000

TMHMM  Annotations      download full data without filtering help

Start End
1109 1131
1225 1242
1257 1279
1299 1321