dbCAN-seq: a database of CAZyme sequence and annotation

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CAZyme Information: KAG2009800.1

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Basic Information help

Species

Coprinopsis cinerea

Lineage

Basidiomycota; Agaricomycetes; ; Psathyrellaceae; Coprinopsis; Coprinopsis cinerea

CAZyme ID

KAG2009800.1

CAZy Family

GH105

CAZyme Description

asparagine-linked glycosylation protein 11

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
408		46151.15	9.4715

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_Ccinerea326	15250	N/A	238	15012

Gene Location

Full Sequence Download help

Enzyme Prediction help

EC	2.4.1.131:1

CAZyme Signature Domains help

Family	Start	End	Evalue	family coverage
GT4	207	368	3.3e-22	0.90625

CDD Domains download full data without filtering help

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
340835	GT4_ALG11-like	2.79e-180	2	395	52	418	alpha-1,2-mannosyltransferase ALG11 and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. ALG11 in yeast is involved in adding the final 1,2-linked Man to the Man5GlcNAc2-PP-Dol synthesized on the cytosolic face of the ER. The deletion analysis of ALG11 was shown to block the early steps of core biosynthesis that takes place on the cytoplasmic face of the ER and lead to a defect in the assembly of lipid-linked oligosaccharides.
215511	PLN02949	4.84e-125	1	393	84	446	transferase, transferring glycosyl groups
406369	ALG11_N	5.86e-93	2	157	52	207	ALG11 mannosyltransferase N-terminus.
340834	GT4_ALG2-like	8.72e-25	176	393	169	388	alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. A deficiency of this enzyme causes an abnormal accumulation of Man1GlcNAc2-PP-dolichol and Man2GlcNAc2-PP-dolichol, which is associated with a type of congenital disorders of glycosylation (CDG), designated CDG-Ii, in humans.
395425	Glycos_transf_1	2.22e-21	210	383	2	158	Glycosyl transferases group 1. Mutations in this domain of PIGA lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.

CAZyme Hits help

Hit ID	E-Value	Query Start	Query End	Hit Start
1.49e-143	1	406	326	711
2.59e-121	1	397	126	589
1.27e-116	1	407	108	559
1.00e-112	1	393	106	469
3.16e-112	65	394	1	312

PDB Hits help

KAG2009800.1 has no PDB hit.

Swiss-Prot Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
6.32e-104	5	394	115	484	GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase OS=Danio rerio OX=7955 GN=alg11 PE=2 SV=2
1.26e-101	7	394	119	480	GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase OS=Mus musculus OX=10090 GN=Alg11 PE=2 SV=1
1.12e-99	7	394	119	480	GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase OS=Homo sapiens OX=9606 GN=ALG11 PE=1 SV=2
2.23e-99	7	394	119	480	GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase OS=Pongo abelii OX=9601 GN=ALG11 PE=2 SV=2
7.46e-99	6	394	114	474	GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase OS=Xenopus laevis OX=8355 GN=alg11 PE=2 SV=2

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000033	0.000005

TMHMM Annotations help

There is no transmembrane helices in KAG2009800.1.