CAZyme Information: KAB8199482.1

Basic Information

• Species: Aspergillus parasiticus
• Lineage: Ascomycota; Eurotiomycetes; ; Aspergillaceae; Aspergillus; Aspergillus parasiticus
• CAZyme ID: KAB8199482.1
• CAZy Family: AA13
• CAZyme Description: glycosyl hydrolases family 31-domain-containing protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
770		85784.04	6.9071

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_AparasiticusCBS117618	14005	N/A	253	13752

• Gene Location: location=ML735074:51316-53681(+)

Full Sequence      

MPPYSSYLGAFSVFALAALGESRSSWTLGQGIEINWQSSPQQLSIVQANKTLLATVPGQN
FLSASAGKDQWVGANGNFNYTNIDRIRCQGQNVTGITHSSREDSVNGEDVSIQGYLQNCG
NQSIGYTMSFWVPKALPDRVAFDVNVEPGHKRNAAMNKLYVTFGSHISEDFYGLGAQASF
ASMKNQTIPIFSREQGVGRGDQPITALEDSQSWFSGGNEFTTYTAIPQYISSAARVFYLR
EEDTAFAEFDFTKPNAVTVRYDALTVGGHIMQADNMLNAITMLTDYVGKMPTLPEWVDNG
AILGIQGGQEKVERIVKEGLKQDCPVAAVWLQDWSGTHSQEAPYGNMQISRLWWNWESDS
KLYPTWTEFVQDLREEYGVKTLAYINPFVANVSSKADGYRRNLFLEATKGGYMVQNSTTN
GTAIISSGKGIQAGILDLTNQKTRTWFTDVLRKQVWNANISGVMWDFGEYTPITPDTKLA
NISSDAYFYHNQYPRDWAIFQRSVAKEMPLFNEMVTFHRSASLGSNRHLNLFWVGDQTTV
WGVNDGIKSAVTIMGQMGISGYAQSHSDLGGYTTAFHPPTVANSSGAIGRSAEILGRWGE
LAAVSSAVFRSHEGNVPEVNAQFYTNSSTYSYYAYNARMFKSLGPYRRQILNNESKTRGW
PLLRMPVLYHPDDSKARQISYQSFYLGADLYVAPVLDPQTTKLNVYLPGTDRNRTYTHVW
SGKTYYAGQTVRVDAPYGKPAVFVVNHAHSPELNVFLDFVRKENGTVIRV

Enzyme Prediction     

No EC number prediction in KAB8199482.1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH31	270	744	4.8e-66	0.9789227166276346

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
236691	PRK10426	9.47e-166	120	744	44	617	alpha-glucosidase; Provisional
269880	GH31_glucosidase_YihQ	2.86e-143	288	637	1	325	alpha-glucosidase YihQ-like. YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs of YihQ that have not yet been functionally characterized are present in plants and fungi. YihQ has sequence similarity to other GH31 enzymes such as CtsZ, a 6-alpha-glucosyltransferase from Bacillus globisporus, and YicI, an alpha-xylosidase from Echerichia coli. These latter two belong to different GH31 subfamilies than YihQ. In bacteria, YihQ (along with YihO) is important for bacterial O-antigen capsule assembly and translocation.
224418	YicI	2.61e-52	215	744	183	664	Alpha-glucosidase, glycosyl hydrolase family GH31 [Carbohydrate transport and metabolism].
395838	Glyco_hydro_31	6.20e-39	270	744	2	436	Glycosyl hydrolases family 31. Glycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases.
269878	GH31_NET37	1.91e-33	308	709	16	361	glucosidase NET37. NET37 (also known as KIAA1161) is a human lamina-associated nuclear envelope transmembrane protein. A member of the glycosyl hydrolase family 31 (GH31) , it has been shown to be required for myogenic differentiation of C2C12 cells. Related proteins are found in eukaryotes and prokaryotes. Enzymes of the GH31 family possess a wide range of different hydrolytic activities including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-xylosidase, 6-alpha-glucosyltransferase, 3-alpha-isomaltosyltransferase and alpha-1,4-glucan lyase. All GH31 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QMW44330.1|GH31	0.0	1	770	1	770
QMW32300.1|GH31	0.0	1	770	1	770
QRD83751.1|GH31	0.0	1	770	1	770
UDD57268.1|GH31	0.0	1	770	1	770
BAE62256.1|GH31	0.0	1	770	1	767

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5AED_A	1.11e-87	153	743	111	661	A bacterial protein structure in glycoside hydrolase family 31 [Escherichia coli K-12],5AED_B A bacterial protein structure in glycoside hydrolase family 31 [Escherichia coli K-12],5AEG_A A bacterial protein structure in glycoside hydrolase family 31. [Escherichia coli K-12],5AEG_B A bacterial protein structure in glycoside hydrolase family 31. [Escherichia coli K-12],5OHT_A A GH31 family sulfoquinovosidase from E. coli in complex with aza-sugar inhibitor IFGSQ [Escherichia coli K-12],5OHT_B A GH31 family sulfoquinovosidase from E. coli in complex with aza-sugar inhibitor IFGSQ [Escherichia coli K-12]
5AEE_A	5.85e-87	153	743	111	661	A bacterial protein structure in glycoside hydrolase family 31 [Escherichia coli K-12],5AEE_B A bacterial protein structure in glycoside hydrolase family 31 [Escherichia coli K-12]
6PNR_A	2.54e-83	151	765	94	666	Chain A, Alpha-glucosidase [[Eubacterium] rectale],6PNR_C Chain C, Alpha-glucosidase [[Eubacterium] rectale]
5OHY_A	3.26e-78	139	743	80	646	Chain A, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],5OHY_B Chain B, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],5OHY_C Chain C, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],5OHY_D Chain D, Alpha-glucosidase yihQ [Agrobacterium tumefaciens]
5OHS_A	1.68e-77	139	743	80	646	Chain A, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],5OHS_B Chain B, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],5OHS_C Chain C, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],5OHS_D Chain D, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],5OHS_E Chain E, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],5OHS_F Chain F, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],5OHS_G Chain G, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],5OHS_H Chain H, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],7OFX_A Chain A, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],7OFX_B Chain B, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],7OFX_C Chain C, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],7OFX_D Chain D, Alpha-glucosidase yihQ [Agrobacterium tumefaciens]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P32138|SQASE_ECOLI	4.78e-87	153	743	111	661	Sulfoquinovosidase OS=Escherichia coli (strain K12) OX=83333 GN=yihQ PE=1 SV=3
sp|B3PEE6|OL4AG_CELJU	2.56e-15	223	708	189	633	Oligosaccharide 4-alpha-D-glucosyltransferase OS=Cellvibrio japonicus (strain Ueda107) OX=498211 GN=agd31B PE=1 SV=1
sp|Q69ZQ1|MYORG_MOUSE	3.30e-13	359	708	365	680	Myogenesis-regulating glycosidase OS=Mus musculus OX=10090 GN=Myorg PE=1 SV=2
sp|Q9F234|AGL2_BACTQ	7.25e-12	168	744	146	668	Alpha-glucosidase 2 OS=Bacillus thermoamyloliquefaciens OX=1425 PE=3 SV=1
sp|Q6NSJ0|MYORG_HUMAN	1.85e-10	355	708	362	678	Myogenesis-regulating glycosidase OS=Homo sapiens OX=9606 GN=MYORG PE=1 SV=2

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.000318	0.999653	CS pos: 22-23. Pr: 0.8666

TMHMM  Annotations     

There is no transmembrane helices in KAB8199482.1.