CAZyme Information: HMPREF1544_11303-t46_1-p1

Basic Information

• Species: Mucor circinelloides
• Lineage: Mucoromycota; Mucoromycetes; ; Mucoraceae; Mucor; Mucor circinelloides
• CAZyme ID: HMPREF1544_11303-t46_1-p1
• CAZy Family: GT5
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
750		84953.55	5.9906

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_Mcircinelloides1006PhL	12410	1220926	183	12227

• Gene Location: location=KE124138:13736-16153(-)

Full Sequence      

MTYLSLSVADQIKGRFRIGGTFYLVVHNVDQEAYITIHGRHDKILLQSLPDLPFVQSSCG
QDQIIAGDGGVFKIIEAVDNPSNTTVSQTIDTITSNDTGLHLNGTIKFTNCQHIGYSFKL
QELSEKQLDFSIQLGIAHDNKDHHRIIFNFKSNAHEDFYGFGEQFSYSTLKGQKVPIFVR
EQGIGRGEEPVTSILNDPSGVFGDFAGGDSFTTYCSVPQFLSTDNRSLVLHNSEYSSFDL
RKDDRVSVRLNATLLEGRLFQGDNLLDLVSEYTSYSGRMHLLPDWISDGAVVGIQGGTQK
VRKVIRQLQHHNTPIAAVWLQDWCGKRLQKTPNGVEFKRLWWNWESDDTLYPDWPTFVND
ELRSQNIRVLSYVNTFLANVEKKQSYRNNYFLEAEAHGYLVKDPSSTSKHQTLIISSGTD
FEAGILDLTNPDAVVWFKSIVKQHVYDAGVSGMMTDFGEYLPYHSEKVSLHSGISSEVYH
NRYPQEWAKLHSELVHEIGLEDEAVCFYRAGFTRTPGFINLMWTGDQNVAWDAHDGIKSA
VTGMLSGGFSGFSITHSDIGGYTTISAAPLLELVRSKELLFRWMELSAFTAVFRTHEGII
PELNAQFYDDEESLAYFAFYAKLYTSLSPYRKKLIQEAHTRGWPLMRHLVFYYLHDPIVR
RITYSQYLLGDSLLVAPMLAPSMSHVKVYLPKEEGVTWRHVWSNQSFTPTGQDISVETPF
QRPAVFIKEPRQDGGLLDEFIAFTAEQSNA

Enzyme Prediction     

No EC number prediction in HMPREF1544_11303-t46_1-p1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH31	260	729	2.1e-82	0.9812646370023419

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
236691	PRK10426	0.0	142	729	68	619	alpha-glucosidase; Provisional
269880	GH31_glucosidase_YihQ	0.0	277	621	1	325	alpha-glucosidase YihQ-like. YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs of YihQ that have not yet been functionally characterized are present in plants and fungi. YihQ has sequence similarity to other GH31 enzymes such as CtsZ, a 6-alpha-glucosyltransferase from Bacillus globisporus, and YicI, an alpha-xylosidase from Echerichia coli. These latter two belong to different GH31 subfamilies than YihQ. In bacteria, YihQ (along with YihO) is important for bacterial O-antigen capsule assembly and translocation.
224418	YicI	1.03e-91	65	729	39	666	Alpha-glucosidase, glycosyl hydrolase family GH31 [Carbohydrate transport and metabolism].
395838	Glyco_hydro_31	1.11e-58	259	729	2	438	Glycosyl hydrolases family 31. Glycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases.
269878	GH31_NET37	8.04e-46	343	692	49	361	glucosidase NET37. NET37 (also known as KIAA1161) is a human lamina-associated nuclear envelope transmembrane protein. A member of the glycosyl hydrolase family 31 (GH31) , it has been shown to be required for myogenic differentiation of C2C12 cells. Related proteins are found in eukaryotes and prokaryotes. Enzymes of the GH31 family possess a wide range of different hydrolytic activities including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-xylosidase, 6-alpha-glucosyltransferase, 3-alpha-isomaltosyltransferase and alpha-1,4-glucan lyase. All GH31 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CDS13477.1|GH31	5.20e-245	12	743	18	757
QIN82013.1|GH31	1.96e-182	88	734	108	727
USW53386.1|GH31	9.37e-179	6	727	23	741
UJO15759.1|GH31	1.32e-175	40	748	50	761
BCS07610.1|GH31	1.65e-173	35	748	42	762

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5AED_A	2.27e-117	134	728	105	663	A bacterial protein structure in glycoside hydrolase family 31 [Escherichia coli K-12],5AED_B A bacterial protein structure in glycoside hydrolase family 31 [Escherichia coli K-12],5AEG_A A bacterial protein structure in glycoside hydrolase family 31. [Escherichia coli K-12],5AEG_B A bacterial protein structure in glycoside hydrolase family 31. [Escherichia coli K-12],5OHT_A A GH31 family sulfoquinovosidase from E. coli in complex with aza-sugar inhibitor IFGSQ [Escherichia coli K-12],5OHT_B A GH31 family sulfoquinovosidase from E. coli in complex with aza-sugar inhibitor IFGSQ [Escherichia coli K-12]
5AEE_A	1.24e-116	134	728	105	663	A bacterial protein structure in glycoside hydrolase family 31 [Escherichia coli K-12],5AEE_B A bacterial protein structure in glycoside hydrolase family 31 [Escherichia coli K-12]
6PNR_A	2.81e-115	145	739	101	660	Chain A, Alpha-glucosidase [[Eubacterium] rectale],6PNR_C Chain C, Alpha-glucosidase [[Eubacterium] rectale]
5OHY_A	1.12e-107	156	728	110	648	Chain A, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],5OHY_B Chain B, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],5OHY_C Chain C, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],5OHY_D Chain D, Alpha-glucosidase yihQ [Agrobacterium tumefaciens]
5OHS_A	6.08e-107	156	728	110	648	Chain A, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],5OHS_B Chain B, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],5OHS_C Chain C, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],5OHS_D Chain D, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],5OHS_E Chain E, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],5OHS_F Chain F, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],5OHS_G Chain G, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],5OHS_H Chain H, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],7OFX_A Chain A, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],7OFX_B Chain B, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],7OFX_C Chain C, Alpha-glucosidase yihQ [Agrobacterium tumefaciens],7OFX_D Chain D, Alpha-glucosidase yihQ [Agrobacterium tumefaciens]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P32138|SQASE_ECOLI	9.38e-117	134	728	105	663	Sulfoquinovosidase OS=Escherichia coli (strain K12) OX=83333 GN=yihQ PE=1 SV=3
sp|Q9F234|AGL2_BACTQ	1.62e-20	156	729	147	670	Alpha-glucosidase 2 OS=Bacillus thermoamyloliquefaciens OX=1425 PE=3 SV=1
sp|D2PPM7|AIMA_KRIFD	1.03e-19	144	731	152	714	1,3-alpha-isomaltosidase OS=Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399) OX=479435 GN=Kfla_1895 PE=1 SV=1
sp|Q8BHN3|GANAB_MOUSE	4.33e-17	259	705	366	783	Neutral alpha-glucosidase AB OS=Mus musculus OX=10090 GN=Ganab PE=1 SV=1
sp|A7LXT0|GH31A_BACO1	7.56e-17	262	728	381	838	Alpha-xylosidase BoGH31A OS=Bacteroides ovatus (strain ATCC 8483 / DSM 1896 / JCM 5824 / BCRC 10623 / CCUG 4943 / NCTC 11153) OX=411476 GN=BACOVA_02646 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000021	0.000000

TMHMM  Annotations     

There is no transmembrane helices in HMPREF1544_11303-t46_1-p1.