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CAZyme Information: HMPREF1544_10788-t46_1-p1
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Mucor circinelloides | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Mucoromycota; Mucoromycetes; ; Mucoraceae; Mucor; Mucor circinelloides | |||||||||||
| CAZyme ID | HMPREF1544_10788-t46_1-p1 | |||||||||||
| CAZy Family | GT48 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | ||||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH15 | 17 | 318 | 3.6e-16 | 0.7728531855955678 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| 395586 | Glyco_hydro_15 | 9.87e-62 | 13 | 231 | 3 | 206 | Glycosyl hydrolases family 15. In higher organisms this family is represented by phosphorylase kinase subunits. |
| 406202 | ILEI | 1.64e-27 | 1131 | 1219 | 1 | 88 | Interleukin-like EMT inducer. ILEI is a family of proteins found in vertebrates. It is heavily involved in the process of the transition from epithelial to mesenchymal tissue - EMT - during all of embryonic development, cancer progression, metastasis, and chronic inflammation/fibrosis. ILEI is upregulated exclusively at the level of translation, and abnormal ILEI expression, ie cytoplasmic over-expression instead of vesicular localization, is associated with EMT in human cancerous tissue. In order to induce and maintain the EMT of hepatocytes in a TGF-beta-independent fashion ILEI needs the cooperation of oncogenic Ras. |
| 260110 | PANDER_like | 1.26e-26 | 1104 | 1229 | 3 | 129 | Domains similar to the Pancreatic-derived factor. FAM3B or PANDER (PANcreatic DERived factor) has been identifed as a regulator of glucose homeostasis and beta cell function. The protein is expressed in the endocrine pancreas and co-secreted with insulin in response to glucose, particularly under conditions of insulin resistance. The protein had initially been predicted to be a member of the four-helical cytokine family, hence the FAM3B designation. This wider family contains FAM3B and FAM4C, N-terminal domains of N-acetylglucosaminyltransferases, and domains in poorly characterized proteins that have been associated with deafness and the progression of cancer. |
| 260112 | PANDER_like_TMEM2 | 1.79e-19 | 1130 | 1229 | 47 | 147 | PANDER-like domain of the transmembrane protein TMEM2. TMEM2 has been characterized as a transmembrane protein that maps to the DFNB7-DFNB11 deafness locus on human chromosome 9. It contains a domain similar to the Pancreatic-derived factor PANDER, C-terminal to a glycine rich G8-domain. The function of the PANDER-like domain in TMEM2 has not been characterized. |
| 260111 | PANDER_GnT-1_2_like | 1.21e-15 | 1111 | 1228 | 6 | 127 | PANDER-like domain of N-acetylglucosaminyltransferases. O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 participates in O-mannosyl glycosylation and may be responsible for creating GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moieties on alpha dystroglycan and other O-mannosylated proteins. The domain characterized by this model lies N-terminal to the catalytic domain. Its function has not been determined. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| 0.0 | 11 | 1219 | 15 | 1234 | |
| 1.97e-240 | 13 | 1040 | 10 | 861 | |
| 1.97e-240 | 13 | 1040 | 10 | 861 | |
| 5.48e-240 | 13 | 1040 | 10 | 861 | |
| 9.89e-240 | 13 | 1040 | 9 | 860 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 2.64e-08 | 1075 | 1219 | 4 | 149 | Long wavelength S-SAD structure of FAM3B PANDER [Mus musculus],2YOP_B Long wavelength S-SAD structure of FAM3B PANDER [Mus musculus],2YOP_C Long wavelength S-SAD structure of FAM3B PANDER [Mus musculus] |
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| 3.40e-08 | 1075 | 1219 | 20 | 165 | Structure of FAM3B PANDER E30 construct [Mus musculus],2YOQ_B Structure of FAM3B PANDER E30 construct [Mus musculus],2YOQ_C Structure of FAM3B PANDER E30 construct [Mus musculus] |
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| 3.06e-06 | 1131 | 1219 | 48 | 134 | Chain A, Protein FAM3A [Mus musculus] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6.54e-214 | 6 | 1350 | 3 | 1149 | Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Mus musculus OX=10090 GN=Phka1 PE=1 SV=3 |
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| 4.22e-213 | 6 | 1350 | 3 | 1144 | Phosphorylase b kinase regulatory subunit alpha, liver isoform OS=Oryctolagus cuniculus OX=9986 GN=PHKA2 PE=2 SV=1 |
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| 9.30e-212 | 6 | 1350 | 3 | 1145 | Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Oryctolagus cuniculus OX=9986 GN=PHKA1 PE=1 SV=1 |
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| 4.37e-210 | 6 | 1350 | 3 | 1150 | Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Rattus norvegicus OX=10116 GN=Phka1 PE=1 SV=2 |
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| 7.10e-210 | 6 | 1350 | 3 | 1144 | Phosphorylase b kinase regulatory subunit alpha, liver isoform OS=Homo sapiens OX=9606 GN=PHKA2 PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | CS Position |
|---|---|---|
| 0.999342 | 0.000673 |