CAZyme Information: HCEG_00724-t36_1-p1

Basic Information

• Species: Histoplasma capsulatum
• Lineage: Ascomycota; Eurotiomycetes; ; Ajellomycetaceae; Histoplasma; Histoplasma capsulatum
• CAZyme ID: HCEG_00724-t36_1-p1
• CAZy Family: AA2
• CAZyme Description: alpha-1,6 mannosyltransferase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
590	DS990636|CGC2	66442.15	10.1679

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_HcapsulatumH88	9666	544711	221	9445

• Gene Location: location=DS990636:2456993-2459037(-)

Full Sequence      

MPRLTDWFLLSLIPGLILLHLYVSPYTKVEESFNIQAIHDISTYGIPTKNAKNRFRTQYD
HFSFPGAVPRTFVGALIVAGIAKPFMWINSQIHWQLLVRGIVGCFNVFALISYARGVRRA
FGKDVAVWYILFQASQFHVIYYASRTLPNMFAFGITTFAFRYLLPEPSSAVQNIQSRKRY
RLSLYLLTIAGVVFRSEIALLLATTTADLWAKKRVNLRSDILPAAISGIIIGLFSTIITD
SIFWQKFPLWPELAAFKYNVISGHASAWGISAWHFYLTNALPRLLLNPVTYTLCIPLSIL
QPSTRPTATSLLLSPLAYIFLYSFQPHKEWRFILYTIPPLTTTAALGASHIWTHRSKKPP
LYHLLAAVLCLSTLTTFAISTLLLLPISATNYPGAHALNALHNNHPYSHNDSRITRQQTI
TVHIDNLSCQTGVTRFLQKSPPKSPLIVLPGTPDGRYPELRSGEQKWVYDKTDAGDVARM
RRADAERFWGQFDYLLAEVVGDGANNMPGRWEVVDEITGFGGVRVLRPGDEFGGDGVGGG
VEEEVLGRLFGDKAVDGWSWVKRVGRKYVTRGWWVEVRMVPKIRVLRNVG

Enzyme Prediction     

No EC number prediction in HCEG_00724-t36_1-p1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT22	16	412	1.4e-83	0.922879177377892

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
281842	Glyco_transf_22	1.60e-33	7	379	2	364	Alg9-like mannosyltransferase family. Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.
215437	PLN02816	2.85e-05	121	338	144	348	mannosyltransferase

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QSS52223.1|GT22	0.0	1	590	1	590
QSS70192.1|GT22	0.0	1	590	1	590
QVM10858.1|GT22	1.21e-230	1	589	1	567
CAK43935.1|GT22	2.68e-212	9	588	25	573
BCS08490.1|GT22	1.29e-209	9	588	10	555

PDB Hits     

HCEG_00724-t36_1-p1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P53730|ALG12_YEAST	1.61e-67	20	520	17	491	Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=ALG12 PE=1 SV=1
sp|Q9VH78|ALG12_DROME	7.57e-65	20	438	12	396	Probable Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase OS=Drosophila melanogaster OX=7227 GN=Alg12 PE=2 SV=1
sp|Q23361|ALG12_CAEEL	2.54e-61	5	502	4	436	Probable Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase OS=Caenorhabditis elegans OX=6239 GN=algn-12 PE=1 SV=2
sp|Q8VDB2|ALG12_MOUSE	8.32e-61	6	438	11	406	Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase OS=Mus musculus OX=10090 GN=Alg12 PE=2 SV=2
sp|Q9USD4|ALG12_SCHPO	1.15e-59	22	498	25	430	Probable Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=alg12 PE=3 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
0.999552	0.000472

TMHMM  Annotations     

Start	End
7	24
67	89
96	115
125	142
184	206
221	243
255	277
307	324
331	353
363	385