CAZyme Information: HCDG_05694-t38_1-p1

Basic Information

• Species: Histoplasma capsulatum
• Lineage: Ascomycota; Eurotiomycetes; ; Ajellomycetaceae; Histoplasma; Histoplasma capsulatum
• CAZyme ID: HCDG_05694-t38_1-p1
• CAZy Family: GH72
• CAZyme Description: beta-N-acetylglucosaminidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
910		99016.75	6.5898

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_HcapsulatumH143	9796	544712	249	9547

• Gene Location: location=GG692427:944770-947864(-)

Full Sequence      

MGFDGTSVNSEIRSLIEDYHLGSVILTAKNLKSAEETTKLVYELQTIARDAGHPVPLLIC
LDQENGGVNTLFDEIYIRQFPSAMGMAATGSKSLAREVCKATAQELSAVGINWILGPVLD
ALTNARNQPLGVRSVGDDPQEVSAYGIEFMKGYQEAGLVTCGKHFPSYGNLDYMGSQSDV
PIITETIEQLSVSALVPYRNAITHGIDSMMVGGCSMASAGMTVMHACLSEQVVDELLRKD
LKFDGVVVSECLEMEALSYNIGVGGGTVMAMKAGCDLILLCRSFSVQQEAINGLKLGVEN
GIISKSRIRESLRRVLDMKSRCTSWEKALNPPGISLLSKMQPSHTSLSTRAYSSSLTVVR
DKHNNIPLSSVLEPDEELLLLTPLIKPLPASAMLLSMTTEASRAGLSADAASWERSASVM
SGESVFKEFGRSLARQRNGRVLHTSYTANGVRPVHENLIDRASAVIVVTADANRNLYQNG
FTKHVSLMCNSQFSPNGERRAKPVIVVAVSSPYDFATDPSIGTYICTYDFTETALQSLVK
ILYGELTPSGSLPGSLSRNQRLQQSRQHWLVENWNEDRDAHALDTLLDIVREDGTQCQRS
ELASVTSTTFLLRNSDVEESHFVVRNSSTQALYGFCSTYYFKSTGTGVIGALIVDPSRRR
MSIGHSLHNRAIRTLIQRPGIRSFQLGSRLPGIYHGIPTGNPTERKRLRQWFANLGWNTA
LSRSVCSMMLRNLEDWSPPEGLTKVLQSSEVDYDLVYGWEFADSVLDHVKTTSRVGVMEI
YKRGLGGAPGSGIIRAKRREDGTILGSVVVYNSTSALAESMPALKDTRTIAGGISCPVIS
PSVGEYATLVQGLILLGIKQIRKQGARAAILDCVDADGNYDSLSAMGFSVLHSFEEVTCD
ASTWSMMAAS

Enzyme Prediction     

No EC number prediction in HCDG_05694-t38_1-p1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH3	54	279	1.3e-51	0.9583333333333334

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
224389	BglX	4.61e-67	1	369	10	351	Periplasmic beta-glucosidase and related glycosidases [Carbohydrate transport and metabolism].
395747	Glyco_hydro_3	4.16e-62	2	316	13	314	Glycosyl hydrolase family 3 N terminal domain.
235417	PRK05337	3.22e-31	5	295	10	294	beta-hexosaminidase; Provisional
178629	PLN03080	1.05e-08	80	553	114	585	Probable beta-xylosidase; Provisional
185053	PRK15098	2.96e-08	79	319	119	353	beta-glucosidase BglX.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QSS62698.1|GH3	0.0	1	910	15	924
QSS50503.1|GH3	0.0	84	910	1	827
QSS74235.1|GH3	0.0	84	910	1	827
BAE65506.1|GH3	0.0	1	910	54	961
QRD92904.1|GH3	0.0	1	910	7	914

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4ZM6_A	3.08e-86	2	740	20	700	A unique GCN5-related glucosamine N-acetyltransferase region exist in the fungal multi-domain GH3 beta-N-acetylglucosaminidase [Rhizomucor miehei CAU432],4ZM6_B A unique GCN5-related glucosamine N-acetyltransferase region exist in the fungal multi-domain GH3 beta-N-acetylglucosaminidase [Rhizomucor miehei CAU432]
6K5J_A	1.50e-60	2	557	24	532	Structure of a glycoside hydrolase family 3 beta-N-acetylglucosaminidase from Paenibacillus sp. str. FPU-7 [Paenibacillaceae]
3BMX_A	6.28e-43	6	553	71	614	Beta-N-hexosaminidase (YbbD) from Bacillus subtilis [Bacillus subtilis],3BMX_B Beta-N-hexosaminidase (YbbD) from Bacillus subtilis [Bacillus subtilis],3NVD_A Structure of YBBD in complex with pugnac [Bacillus subtilis],3NVD_B Structure of YBBD in complex with pugnac [Bacillus subtilis]
3LK6_A	8.30e-43	6	553	45	588	Chain A, Lipoprotein ybbD [Bacillus subtilis],3LK6_B Chain B, Lipoprotein ybbD [Bacillus subtilis],3LK6_C Chain C, Lipoprotein ybbD [Bacillus subtilis],3LK6_D Chain D, Lipoprotein ybbD [Bacillus subtilis]
4GYJ_A	1.21e-42	6	553	75	618	Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1) [Bacillus subtilis subsp. subtilis str. 168],4GYJ_B Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1) [Bacillus subtilis subsp. subtilis str. 168],4GYK_A Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1211) [Bacillus subtilis subsp. subtilis str. 168],4GYK_B Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1211) [Bacillus subtilis subsp. subtilis str. 168]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P40406|NAGZ_BACSU	3.23e-42	6	553	71	614	Beta-hexosaminidase OS=Bacillus subtilis (strain 168) OX=224308 GN=nagZ PE=1 SV=1
sp|Q7WUL3|NAG3_CELFI	1.88e-34	15	553	51	552	Beta-N-acetylglucosaminidase/beta-glucosidase OS=Cellulomonas fimi OX=1708 GN=nag3 PE=1 SV=1
sp|P48823|HEXA_PSEO7	8.66e-29	6	553	49	593	Beta-hexosaminidase A OS=Pseudoalteromonas piscicida OX=43662 GN=cht60 PE=1 SV=1
sp|Q3SKU2|NAGZ_THIDA	3.01e-27	5	291	12	293	Beta-hexosaminidase OS=Thiobacillus denitrificans (strain ATCC 25259) OX=292415 GN=nagZ PE=3 SV=1
sp|Q6LJ30|NAGZ_PHOPR	9.50e-26	5	294	10	287	Beta-hexosaminidase OS=Photobacterium profundum (strain SS9) OX=298386 GN=nagZ PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000071	0.000000

TMHMM  Annotations     

There is no transmembrane helices in HCDG_05694-t38_1-p1.