CAZyme Information: HCDG_03729-t38_1-p1

Basic Information

• Species: Histoplasma capsulatum
• Lineage: Ascomycota; Eurotiomycetes; ; Ajellomycetaceae; Histoplasma; Histoplasma capsulatum
• CAZyme ID: HCDG_03729-t38_1-p1
• CAZy Family: GH2
• CAZyme Description: asparagine-linked glycosylation 9 protein isoform a

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
586		66556.36	9.3876

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_HcapsulatumH143	9796	544712	249	9547

• Gene Location: location=GG692422:1645849-1647806(-)

Full Sequence      

MPSKQSQLAGSYSYESSVEGASKSSPKYVTLSHRADLLAPIQDCDEVFNYWEPTHYLVHG
YGLQTWEYSPEYSIRSWLYVSLHAGIAKISTLVTQSKTAQFYFVRMALAFICAACETRIF
AAISRTLHPRIGVIFVTIMVFSPGIFHASTAMLPSSFTMYTSMLGISAFMDWRGGLNTGR
GIMWFGIGAIVGWPFAGALVVSFLLEEVLIGYGSEFLHRTLIRFTEGVIKCLVVLVLEVV
TDSLFYRKLVVVPWNIVSYNVFGGSNKGPNIFGTEPWTFYFRNLLLNFNIWFLLALSAAP
LLILQTVFRPRDTSKQTILRTVALLLPFYIWLGIFTIQPHKEERFMYAAYPFLALNAAIA
FHNILAYLGSSNRKEFIGRVPRKVKLAIALMPVLLATNISLLRTLGIVTAYSAPLQLFQP
LENPEVAAHGDHVCFGKEWYRFPSSFFLPDKKRAKFIKNEFNGLLPGEFTTEADGRGPRP
GTWMVPSGMNDQNQEDPGKYQMNISQCNFLVDSYFPGDEGSALQPNYVLDKSTWEEISCR
RFLDTKRTSLLGRIIWIPDLPFIPEKLQRKWGRYCLLRRRNFDTRP

Enzyme Prediction     

EC	2.4.1.259:12	2.4.1.261:12

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT22	37	449	2.4e-97	0.961439588688946

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
281842	Glyco_transf_22	1.82e-85	37	449	15	414	Alg9-like mannosyltransferase family. Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.
215437	PLN02816	0.005	242	401	258	404	mannosyltransferase

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QSS49797.1|GT22	0.0	1	586	1	601
QSS60134.1|GT22	0.0	1	586	1	602
QSS68289.1|GT22	0.0	1	586	1	601
EAA65371.1|GT22	1.40e-269	35	584	47	595
BCS18456.1|GT22	5.16e-269	35	580	47	591

PDB Hits     

HCDG_03729-t38_1-p1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q9P7Q9|ALG9_SCHPO	2.61e-119	41	577	34	557	Alpha-1,2-mannosyltransferase alg9 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=alg9 PE=3 SV=1
sp|Q9H6U8|ALG9_HUMAN	1.21e-101	35	560	72	584	Alpha-1,2-mannosyltransferase ALG9 OS=Homo sapiens OX=9606 GN=ALG9 PE=1 SV=2
sp|Q8VDI9|ALG9_MOUSE	9.34e-101	35	560	72	584	Alpha-1,2-mannosyltransferase ALG9 OS=Mus musculus OX=10090 GN=Alg9 PE=2 SV=1
sp|P53868|ALG9_YEAST	1.15e-87	41	559	28	519	Alpha-1,2-mannosyltransferase ALG9 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=ALG9 PE=1 SV=1
sp|Q9FZ49|ALG9_ARATH	8.32e-77	41	579	66	567	Dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase OS=Arabidopsis thaliana OX=3702 GN=ALG9 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000015	0.000003

TMHMM  Annotations     

Start	End
102	124
131	153
182	204
224	246
284	306
318	337
347	369
386	408