CAZyme Information: HCDG_03045-t38_1-p1

Basic Information

• Species: Histoplasma capsulatum
• Lineage: Ascomycota; Eurotiomycetes; ; Ajellomycetaceae; Histoplasma; Histoplasma capsulatum
• CAZyme ID: HCDG_03045-t38_1-p1
• CAZy Family: GH17
• CAZyme Description: glycosyl hydrolase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
317	GG692421|CGC9	35704.02	6.9133

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_HcapsulatumH143	9796	544712	249	9547

• Gene Location: location=GG692421:2348364-2349788(+)

Full Sequence      

MSQLEMSIKASLQRWESANRLTGNTSPETEIYLQFLPSTSSNIMVVLQAFVLVWFFFVSD
AQGKSNYKSHAEAGLKTLQKWYNTTTGLWETTGWWNGGNCLTTIADFAIFDEQAASVGHT
VFLTTFAKAQKANFRFHKRILPNGLVDTNYLKPSSDGSQLQNRGNPGFINDYYDDEGWWA
LGWVQVYDLTGDPKYLNMAEDIFEDMTRGWDDSRCGGGIWWDKNQTALVAIANELFLSVA
AHLATRVHHKANHYHSWATKGWYWFKKTGMINERNNNAKNEKDQFGVNWVGPFAGPALAS
TQSSALDALVAAAAIRR

Enzyme Prediction     

No EC number prediction in HCDG_03045-t38_1-p1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH76	71	275	5.9e-44	0.49162011173184356

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
397638	Glyco_hydro_76	2.78e-15	170	275	83	196	Glycosyl hydrolase family 76. Family of alpha-1,6-mannanases.
227170	COG4833	1.18e-04	169	268	88	181	Predicted alpha-1,6-mannanase, GH76 family [Carbohydrate transport and metabolism].
395616	Glyco_hydro_9	0.005	157	260	194	286	Glycosyl hydrolase family 9.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QSS56711.1|GH76	4.12e-189	44	317	1	387
QSS71561.1|GH76	3.38e-188	44	317	1	387
QSS61749.1|GH76	3.20e-154	1	317	1	371
AUW31385.1|GH76	7.68e-61	69	276	33	238
ANM86558.1|GH76	7.68e-61	69	276	33	238

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4BOK_A	1.48e-09	170	266	86	182	Chain A, Alpha-1,6-mannanase [Niallia circulans]
4BOJ_A	1.50e-09	170	266	89	185	Chain A, Alpha-1,6-mannanase [Niallia circulans],4BOJ_B Chain B, Alpha-1,6-mannanase [Niallia circulans],4BOJ_C Chain C, Alpha-1,6-mannanase [Niallia circulans]
4D4A_A	1.60e-09	170	266	107	203	Chain A, Alpha-1,6-mannanase [Niallia circulans],4D4A_B Chain B, Alpha-1,6-mannanase [Niallia circulans],4D4B_A Chain A, Alpha-1,6-mannanase [Niallia circulans],4D4B_B Chain B, Alpha-1,6-mannanase [Niallia circulans],4D4C_A Chain A, Alpha-1,6-mannanase [Niallia circulans],4D4C_B Chain B, Alpha-1,6-mannanase [Niallia circulans],4D4D_A Chain A, Alpha-1,6-mannanase [Niallia circulans],4D4D_B Chain B, Alpha-1,6-mannanase [Niallia circulans],5N0F_A Chain A, Alpha-1,6-mannanase [Niallia circulans],5N0F_B Chain B, Alpha-1,6-mannanase [Niallia circulans],6ZBX_A Chain A, Alpha-1,6-mannanase [Niallia circulans],6ZBX_B Chain B, Alpha-1,6-mannanase [Niallia circulans],7NL5_A Chain A, Alpha-1,6-mannanase [Niallia circulans]
5M77_A	2.28e-09	170	266	120	216	Chain A, Alpha-1,6-mannanase [Niallia circulans],5M77_B Chain B, Alpha-1,6-mannanase [Niallia circulans]
5AGD_A	6.86e-09	170	266	107	203	Chain A, Alpha-1,6-mannanase [Niallia circulans],5AGD_B Chain B, Alpha-1,6-mannanase [Niallia circulans],6ZBM_A Chain A, Alpha-1,6-mannanase [Niallia circulans],6ZBW_A Chain A, Alpha-1,6-mannanase [Niallia circulans],6ZBW_B Chain B, Alpha-1,6-mannanase [Niallia circulans]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q5ACZ2|DFG5_CANAL	4.28e-07	82	276	52	229	Mannan endo-1,6-alpha-mannosidase DFG5 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=DFG5 PE=1 SV=1
sp|Q9P6I3|YHG7_SCHPO	5.64e-07	82	271	44	213	Putative mannan endo-1,6-alpha-mannosidase C1198.07c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPBC1198.07c PE=3 SV=2
sp|Q9P6I4|YHG6_SCHPO	7.77e-07	145	272	83	217	Putative mannan endo-1,6-alpha-mannosidase C1198.06c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPBC1198.06c PE=3 SV=1
sp|O74556|YCZ2_SCHPO	9.95e-06	143	273	86	223	Putative mannan endo-1,6-alpha-mannosidase C970.02 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPCC970.02 PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
0.999800	0.000203

TMHMM  Annotations     

There is no transmembrane helices in HCDG_03045-t38_1-p1.