CAZyme Information: HCDG_01000-t38_1-p1

Basic Information

• Species: Histoplasma capsulatum
• Lineage: Ascomycota; Eurotiomycetes; ; Ajellomycetaceae; Histoplasma; Histoplasma capsulatum
• CAZyme ID: HCDG_01000-t38_1-p1
• CAZy Family: AA3
• CAZyme Description: alpha-1,6-mannosyltransferase subunit

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
573		64353.75	10.1986

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_HcapsulatumH143	9796	544712	249	9547

• Gene Location: location=GG692419:4040020-4042063(-)

Full Sequence      

MPRLTDWFLLSLIPGLILLHLYVSPYTKVEESFNIQAIHDISTYGIPTKNAKNRFRTQYD
HFSFPGAVPRTFVGALIVAGIAKPFMWINSQIHWQLLVRGIVGCFNVFALISYARGVRRA
FGKDVAVWTLPNMFAFGITTFAFRYLLPEPSSAVQNIQSRKRYRLSLYLLTIAGVVFRSE
IALLLATTTADLWAKKRVNLRSDILPAAISGIIIGLFSTIITDSIFWQKFPLWPELAAFK
YNVISGHASAWGISAWHFYLTNALPRLLLNPVTYTLCIPLSILQPSTRPTATSLLLSPLA
YIFLYSFQPHKEWRFILYTIPPLTTTAALGASHIWTHRSKKPPLYHLLAAVLCLSTLTTF
AISTLLLLPISATNYPGAHALNALHNNHPYSHNDSRITRQQTITVHIDNLSCQTGVTRFL
QKSPPKSPLIVLPGTPDGRYPELRSGEQKWVYDKTDAGDVARMRRADAERFWGQFDYLLA
EVVGDGANNMPGRWEVVDEITGFGGVRVLRPGDEFGGDGVGGGVEEEVLGRLFGDKAVDG
WSWVKRVGRKYVTRGWWVEVRMVPKIRVLRNVG

Enzyme Prediction     

No EC number prediction in HCDG_01000-t38_1-p1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT22	16	395	3.8e-71	0.922879177377892

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
281842	Glyco_transf_22	3.51e-26	7	362	2	364	Alg9-like mannosyltransferase family. Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.
215437	PLN02816	0.009	209	321	246	348	mannosyltransferase

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QSS52223.1|GT22	0.0	1	573	1	590
QSS70192.1|GT22	0.0	1	573	1	590
QVM10858.1|GT22	3.83e-215	1	572	1	567
CAK43935.1|GT22	1.00e-197	9	571	25	573
BCS08490.1|GT22	1.96e-194	9	571	10	555

PDB Hits     

HCDG_01000-t38_1-p1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P53730|ALG12_YEAST	6.43e-59	20	503	17	491	Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=ALG12 PE=1 SV=1
sp|Q9VH78|ALG12_DROME	3.03e-57	20	421	12	396	Probable Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase OS=Drosophila melanogaster OX=7227 GN=Alg12 PE=2 SV=1
sp|Q23361|ALG12_CAEEL	1.34e-52	5	485	4	436	Probable Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase OS=Caenorhabditis elegans OX=6239 GN=algn-12 PE=1 SV=2
sp|Q8VDB2|ALG12_MOUSE	8.43e-52	6	421	11	406	Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase OS=Mus musculus OX=10090 GN=Alg12 PE=2 SV=2
sp|Q9BV10|ALG12_HUMAN	4.49e-51	9	421	13	407	Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase OS=Homo sapiens OX=9606 GN=ALG12 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
0.999552	0.000472

TMHMM  Annotations     

Start	End
7	24
67	89
96	115
125	147
167	189
204	226
238	260
290	307
314	336
346	368