CAZyme Information: HCBG_02110-t26_1-p1

Basic Information

• Species: Histoplasma capsulatum
• Lineage: Ascomycota; Eurotiomycetes; ; Ajellomycetaceae; Histoplasma; Histoplasma capsulatum
• CAZyme ID: HCBG_02110-t26_1-p1
• CAZy Family: GH125
• CAZyme Description: GPI mannosyltransferase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
624		70312.07	8.9982

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_HcapsulatumG186AR	9364	447093	110	9254

• Gene Location: location=GG663364:2718368-2720644(+)

Full Sequence      

MFRRTYLLLLVVRIYFAFSPSYLHPDENFQGPEIFAGQIFNYPSKPTWEFTSDRPIRSVF
PLWLFYGVPMTLLKWLWAEDGTGNTPPELIYYVLRGSMFVLSFVMEDWAIHELVASSSRL
RRQTVVLVASSYVTWTFQTHTFSNSLETLLVVWSLVLIQRILENKQNSSIFACVVLSFLL
VAGVFNRITFPAFVLIPGLRLVPHFLRKPLSLLTVIVFGLISCFIAIFIDTNFYSASVTS
LSDVFHNPIITPLNNLFYNSDVSNLANHGLHPRYNHFLVNLPQLLGPIYLLLLYSFISSS
VRSFFSLRNLRAISALSATVLLSIFPHQEPRFLIPCVALLLTCFRPPRSRFFLASWVLFN
AALGILMGIYHQGGVIPTQLNLPTLLANSTAPLTSSPGSGGMNSKPDDPMPMRMPSGTAT
AFWWKTYSPPSWMLGDLSNTSVPHLTFSSISTIDLMGIPGPEMMERLERSVPKCESDRRP
KHGKPAAKRNHQHQQLDPNAGNDDSAVNSNNNYNNKVTIQHDNPTLLIAPNSNTFLDRYV
AVRTGSASAADADAVADRTNENEEKDRGSLHSLQLHLLWSYARHLNLDDMDFGEDGVWPT
LKRVVGRRGLNVWLVRRRGCLDGN

Enzyme Prediction     

EC	2.4.1.-:4

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT22	5	433	2.4e-80	0.9897172236503856

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
281842	Glyco_transf_22	2.29e-54	5	434	2	412	Alg9-like mannosyltransferase family. Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.
215437	PLN02816	0.003	3	341	39	351	mannosyltransferase

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QSS72479.1|GT22	0.0	1	624	1	624
QSS55894.1|GT22	0.0	1	624	1	624
QVM11889.1|GT22	6.24e-237	1	617	1	549
BCS03934.1|GT22	2.87e-219	1	621	1	537
BCS15543.1|GT22	2.87e-219	1	621	1	537

PDB Hits     

HCBG_02110-t26_1-p1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q2UTP0|SMP3_ASPOR	2.21e-215	1	620	1	542	GPI mannosyltransferase 4 OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) OX=510516 GN=smp3 PE=3 SV=1
sp|Q4WTT7|SMP3_ASPFU	4.37e-201	1	620	1	546	GPI mannosyltransferase 4 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=smp3 PE=3 SV=2
sp|Q5BAX7|SMP3_EMENI	1.11e-198	1	620	1	541	GPI mannosyltransferase 4 OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=smp3 PE=3 SV=2
sp|Q4I785|SMP3_GIBZE	5.04e-158	1	617	1	513	GPI mannosyltransferase 4 OS=Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) OX=229533 GN=SMP3 PE=3 SV=2
sp|Q6CDD0|SMP3_YARLI	1.24e-77	10	435	13	398	GPI mannosyltransferase 4 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) OX=284591 GN=SMP3 PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
0.596361	0.403638

TMHMM  Annotations     

Start	End
168	190
210	229
284	306
351	373