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CAZyme Information: HCAG_08008-t26_1-p1

You are here: Home > Sequence: HCAG_08008-t26_1-p1

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Histoplasma capsulatum
Lineage Ascomycota; Eurotiomycetes; ; Ajellomycetaceae; Histoplasma; Histoplasma capsulatum
CAZyme ID HCAG_08008-t26_1-p1
CAZy Family GT34
CAZyme Description chitin synthase 2
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1277 141213.21 8.0877
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_HcapsulatumNAm1 9402 339724 89 9313
Gene Location

Full Sequence      Download help

Enzyme Prediction      help

EC 2.4.1.16:26 2.4.1.16:26

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT2 547 709 1.2e-78 0.9938650306748467
GT2 687 877 8.3e-22 0.35294117647058826

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
396286 Chitin_synth_1 2.65e-112 547 709 1 163
Chitin synthase. This region is found commonly in chitin synthases classes I, II and III. Chitin a linear homopolymer of GlcNAc residues, it is an important component of the cell wall of fungi and is synthesized on the cytoplasmic surface of the cell membrane by membrane bound chitin synthases.
133033 Chitin_synth_C 2.19e-95 543 863 1 244
C-terminal domain of Chitin Synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin. Chitin synthase, also called UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyltransferase, catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of GlcNAc residues formed by covalent beta-1,4 linkages. Chitin is an important component of the cell wall of fungi and bacteria and it is synthesized on the cytoplasmic surface of the cell membrane by membrane bound chitin synthases. Studies with fungi have revealed that most of them contain more than one chitin synthase gene. At least five subclasses of chitin synthases have been identified.
400626 Chitin_synth_1N 1.25e-33 476 546 1 70
Chitin synthase N-terminal. This is the N-terminal domain of Chitin synthase (pfam01644).
224136 BcsA 5.82e-31 658 999 115 416
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility].
367353 Chitin_synth_2 2.76e-20 688 858 205 372
Chitin synthase. Members of this family are fungal chitin synthase EC:2.4.1.16 enzymes. They catalyze chitin synthesis as follows: UDP-N-acetyl-D-glucosamine + {(1,4)-(N-acetyl-beta-D-glucosaminyl)}(N) <=> UDP + {(1,4)-(N-acetyl-beta-D-glucosaminyl)}(N+1).

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
0.0 1 1277 1 1200
0.0 243 1277 3 1043
0.0 204 1277 8 1063
0.0 15 1277 15 1217
0.0 292 1277 100 1072

PDB Hits      help

HCAG_08008-t26_1-p1 has no PDB hit.

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
0.0 316 1207 152 1060
Chitin synthase 2 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=chs-2 PE=3 SV=4
0.0 309 1277 66 1012
Chitin synthase A OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=chsA PE=3 SV=2
0.0 490 1227 211 954
Chitin synthase 1 OS=Exophiala dermatitidis OX=5970 GN=CHS1 PE=3 SV=2
0.0 243 1277 3 1043
Chitin synthase 2 OS=Paracoccidioides brasiliensis OX=121759 GN=CHS2 PE=3 SV=2
8.35e-300 451 1197 86 838
Chitin synthase 1 OS=Phycomyces blakesleeanus (strain ATCC 8743b / DSM 1359 / FGSC 10004 / NBRC 33097 / NRRL 1555) OX=763407 GN=chs1 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI CS Position
1.000042 0.000005

TMHMM  Annotations      download full data without filtering help

Start End
896 918
931 953
968 990
1010 1032
1042 1061
1139 1161
1176 1198