CAZyme Information: HCAG_04981-t26_1-p1

Basic Information

• Species: Histoplasma capsulatum
• Lineage: Ascomycota; Eurotiomycetes; ; Ajellomycetaceae; Histoplasma; Histoplasma capsulatum
• CAZyme ID: HCAG_04981-t26_1-p1
• CAZy Family: GH47
• CAZyme Description: predicted protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
535	CH476659|CGC11	59396.28	5.1604

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_HcapsulatumNAm1	9402	339724	89	9313

• Gene Location: location=CH476659:397204-398974(+)

Full Sequence      

MFLAMRLSGYSILISILLGWYGVAFKIPDIGHRHPSAHQSDPLETETIFLNFNERNTAPS
RCEFACTYLSKTYADTVAFPGSDNYRQFQASFWSQQQSKTQPMCIFHPKNVSQVSFAMFV
ITQVNCTFAVRSGGHAPFPGASNIQDGMAFDMRSINDIIVTPDRKTAILGTGNTWYDVYK
ALEVHDLIAVGARAGDVGVGGHILGGGISFLSNLYGWACDNVINYEVVGAYGGILNIDAQ
KPEMFFALCGGGNNFGIVTRFTVNIYPQGPMWQGLREFSMDHKQAVLDTYVNLGRAIIND
PRSNNGFIAFTVTQEAERIRAHLENADGIPYPPIFAEMEAIPAVFESSKVQYMSEITKAL
ANETPPGSRYTHWTYTFKVDAWLVRFVADTFLATINPLRAIMGIVVECNFQTVTEPMLSQ
MKGNAFGLSVEGGPYTLLLLSASWPNEADDETIYRAFSNMIQIIKEEANESGVHTNYLFM
NYASQFQDVISSYGPDNVQRLRVASYNDDPEGFLRELQPGYFKLNGSAPAELRKG

Enzyme Prediction     

No EC number prediction in HCAG_04981-t26_1-p1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
AA7	93	295	5.8e-46	0.44541484716157204

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
396238	FAD_binding_4	1.50e-11	102	238	1	139	FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidizes the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.
223354	GlcD	8.37e-08	102	286	32	228	FAD/FMN-containing dehydrogenase [Energy production and conversion].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
UNI23960.1|AA7	6.17e-17	77	314	24	263
CDR44461.1|AA7	5.36e-15	82	266	52	236
QUC19098.1|AA7	1.42e-14	77	314	24	263
UPK90596.1|AA7	2.26e-14	102	314	20	235
QRD93627.1|AA7	6.03e-14	77	267	24	215

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6FYD_A	4.61e-21	104	287	51	230	The crystal structure of EncM T139V mutant [Streptomyces maritimus],6FYD_B The crystal structure of EncM T139V mutant [Streptomyces maritimus],6FYD_C The crystal structure of EncM T139V mutant [Streptomyces maritimus],6FYD_D The crystal structure of EncM T139V mutant [Streptomyces maritimus]
6FYG_A	8.26e-21	104	287	51	230	The crystal structure of EncM V135T mutant [Streptomyces maritimus],6FYG_B The crystal structure of EncM V135T mutant [Streptomyces maritimus],6FYG_C The crystal structure of EncM V135T mutant [Streptomyces maritimus],6FYG_D The crystal structure of EncM V135T mutant [Streptomyces maritimus]
6FYF_A	8.26e-21	104	287	51	230	The crystal structure of EncM V135M mutant [Streptomyces maritimus],6FYF_B The crystal structure of EncM V135M mutant [Streptomyces maritimus],6FYF_C The crystal structure of EncM V135M mutant [Streptomyces maritimus],6FYF_D The crystal structure of EncM V135M mutant [Streptomyces maritimus]
6FYB_A	1.11e-20	104	287	51	230	The crystal structure of EncM L144M mutant [Streptomyces maritimus],6FYB_B The crystal structure of EncM L144M mutant [Streptomyces maritimus],6FYB_C The crystal structure of EncM L144M mutant [Streptomyces maritimus],6FYB_D The crystal structure of EncM L144M mutant [Streptomyces maritimus],6FYC_A The crystal structure of EncM L144M mutant complex with dioxygen under 15 bars O2 pressure [Streptomyces maritimus],6FYC_B The crystal structure of EncM L144M mutant complex with dioxygen under 15 bars O2 pressure [Streptomyces maritimus]
6FYE_A	1.48e-20	104	287	51	230	The crystal structure of EncM H138T mutant [Streptomyces maritimus],6FYE_B The crystal structure of EncM H138T mutant [Streptomyces maritimus]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|M2T7Z1|TPCD_COCH5	9.33e-77	62	525	30	518	FAD-dependent monooxygenase tpcD OS=Cochliobolus heterostrophus (strain C5 / ATCC 48332 / race O) OX=701091 GN=tpcD PE=1 SV=1
sp|A0A023I4D6|PRX3_PENRO	2.93e-64	65	527	31	510	FAD-dependent monooxygenase prx3 OS=Penicillium roqueforti OX=5082 GN=prx3 PE=3 SV=1
sp|W6Q5R7|PRX3_PENRF	2.93e-64	65	527	31	510	FAD-dependent monooxygenase prx3 OS=Penicillium roqueforti (strain FM164) OX=1365484 GN=prx3 PE=3 SV=1
sp|A0A0U5GQ05|DRTC_ASPCI	2.86e-62	66	534	45	523	FAD-dependent monooxygenase drtC OS=Aspergillus calidoustus OX=454130 GN=drtC PE=1 SV=1
sp|B6H064|PRX3_PENRW	8.74e-61	65	527	31	510	FAD-dependent monooxygenase prx3 OS=Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255) OX=500485 GN=prx3 PE=2 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
0.941804	0.058228

TMHMM  Annotations     

Start	End
7	24