CAZyme Information: HCAG_03810-t26_1-p1

Basic Information

• Species: Histoplasma capsulatum
• Lineage: Ascomycota; Eurotiomycetes; ; Ajellomycetaceae; Histoplasma; Histoplasma capsulatum
• CAZyme ID: HCAG_03810-t26_1-p1
• CAZy Family: GH18
• CAZyme Description: conserved hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
855	CH476657|CGC6	100174.00	5.6955

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_HcapsulatumNAm1	9402	339724	89	9313

• Gene Location: location=CH476657:2218612-2222162(+)

Full Sequence      

MDDSQYRCEEEKRLHEDRKRIKYWKKWGPYVAERQWATARTEMHGVHSYMKYLYKYPQKK
FPYQDLVEENARRGKQDREYQILDTGIFEDNRYWDIFIETAKEDEDELLFRVIAYNRGPE
PAPLHIIPHVWYIVDEEKEAINPECQGTKFAAWYAFDEGDGVPPGECAVVRFRISKRNDL
YVDEEVLDNIIEKRVEEADDFYYRISPLPMADDLRNIQRQALSGMMWTKQHYQFIWDQWA
EGDPGLPPPPSERKAIRNQKWKHLHIDDVLSMPDSWEYPFFAAWDTAFHCIPLAMVDPEF
SKKQLDLLTREWYMHPNGQIPAYEWNFGDVNPPVHAWAVFRIFKIERKMYGRQDLDFLER
VFQKLLMNFTWWVNRKDFDGKNIFEGGFLGLDNIGLFNRSEPLPTGGVLEQADSTGWMAF
YSLSMLNIALELAKHRRIYEDIASKFFEHFILISDAMTFRVGNEQSSLWNEEDGFYYDAI
SYGGPWSHQLPVRSLVGLIPLYAVLTLEPELINKFPDFKRRMNWFIDNKFDVAERNIASM
KRRGKDDRRLLSLVSKERLEKILKRMLDETEFLADHGIRSMSKYHSKHPYSMEVNGQEFK
VGYVPGDSDSGLFGGNSNWRGPIWLCVNFLLIESLLRFHMFYGDSFRIECPTGSGDYMNL
GQVAEEIQHRLQHLFVRGDDDRRAVNGGNNILDFDPHWKDYLWFHEFFDADTGRGLGASH
QCGWTGLIAKMIHDTGITCRLPHTPRTPVTAASHYFDDILSRFSKPRPSKSQMLRRSSTS
RSIGQRSSFASTQAGDESVSMYPFESSPRMLGEGDTPGVNEQTRNYVHEQVEFLARRVSV
GVYEDEFKAGADEQE

Enzyme Prediction     

No EC number prediction in HCAG_03810-t26_1-p1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH63	282	734	2.2e-16	0.35789473684210527

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
397353	Glyco_hydro_63	1.97e-11	279	728	87	488	Glycosyl hydrolase family 63 C-terminal domain. This is a family of eukaryotic enzymes belonging to glycosyl hydrolase family 63. They catalyze the specific cleavage of the non-reducing terminal glucose residue from Glc(3)Man(9)GlcNAc(2). Mannosyl oligosaccharide glucosidase EC:3.2.1.106 is the first enzyme in the N-linked oligosaccharide processing pathway. This family represents the C-terminal catalytic domain.
236653	PRK10137	0.006	325	387	412	468	alpha-glucosidase; Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QSS71982.1|GH0	0.0	50	855	1	891
QSS57151.1|GH0	0.0	50	855	1	891
QSS61281.1|GH0	0.0	132	855	74	797
QGA19611.1|GH0	0.0	1	852	4	1018
QMW30137.1|GH0	0.0	1	852	4	999

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4J5T_A	4.92e-07	551	732	667	800	Crystal structure of Processing alpha-Glucosidase I [Saccharomyces cerevisiae S288C]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q04336|YM54_YEAST	2.69e-314	10	744	14	953	Uncharacterized protein YMR196W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=YMR196W PE=1 SV=1
sp|O14255|GCS1_SCHPO	2.53e-06	558	734	683	806	Probable mannosyl-oligosaccharide glucosidase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPAC6G10.09 PE=3 SV=1
sp|P53008|CWH41_YEAST	2.55e-06	551	732	697	830	Mannosyl-oligosaccharide glucosidase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=CWH41 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000065	0.000000

TMHMM  Annotations     

There is no transmembrane helices in HCAG_03810-t26_1-p1.