dbCAN-seq: a database of CAZyme sequence and annotation

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CAZyme Information: H257_12224-t26_1-p1

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Basic Information help

Species

Aphanomyces astaci

Lineage

Oomycota; NA; ; Saprolegniaceae; Aphanomyces; Aphanomyces astaci

CAZyme ID

H257_12224-t26_1-p1

CAZy Family

GT20

CAZyme Description

hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
366		40888.39	5.9449

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_AastaciAPO3	19584	N/A	465	19119

Gene Location

Full Sequence Download help

Enzyme Prediction help

No EC number prediction in H257_12224-t26_1-p1.

CAZyme Signature Domains help

Family	Start	End	Evalue	family coverage
GH18	85	357	1.8e-22	0.9222972972972973

CDD Domains download full data without filtering help

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
119355	GH18_SI-CLP	1.03e-103	80	366	1	318	Stabilin-1 interacting chitinase-like protein (SI-CLP) is a eukaryotic chitinase-like protein of unknown function that interacts with the endocytic/sorting transmembrane receptor stabilin-1 and is secreted from the lysosome. SI-CLP has a glycosyl hydrolase family 18 (GH18) domain but lacks a chitin-binding domain. The catalytic amino acids of the GH18 domain are not conserved in SI-CLP, similar to the chitolectins YKL-39, YKL-40, and YM1/2. Human SI-CLP is sorted to late endosomes and secretory lysosomes in alternatively activated macrophages.
119353	GH18_CFLE_spore_hydrolase	2.19e-15	84	366	4	313	Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in bacterial endospore germination. CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells. SleB translocates across the forespore inner membrane and is deposited as a mature enzyme in the cortex layer of the spore. As part of a sensory mechanism capable of initiating germination, CFLE degrades a spore-specific peptidoglycan constituent called muramic-acid delta-lactam that comprises the outer cortex. CFLE has a C-terminal glycosyl hydrolase family 18 (GH18) catalytic domain as well as two N-terminal LysM peptidoglycan-binding domains. In addition to SleB, this family includes YaaH, YdhD, and YvbX from Bacillus subtilis.
214753	Glyco_18	9.37e-14	85	357	3	333	Glyco_18 domain.
395573	Glyco_hydro_18	1.90e-09	162	357	85	306	Glycosyl hydrolases family 18.
226376	YaaH	9.68e-08	198	366	229	418	Spore germination protein YaaH [Cell cycle control, cell division, chromosome partitioning].

CAZyme Hits help

Hit ID	E-Value	Query Start	Query End	Hit Start
4.35e-86	35	366	67	382
2.47e-76	62	357	502	801
2.59e-76	62	357	505	804
2.72e-76	62	357	508	807
2.72e-76	62	357	508	807

PDB Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6.43e-67	49	366	45	393	Crystal Structure of Stabilin-1 Interacting Chitinase-Like Protein, SI-CLP [Homo sapiens],3BXW_B Crystal Structure of Stabilin-1 Interacting Chitinase-Like Protein, SI-CLP [Homo sapiens]

Swiss-Prot Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
1.51e-67	49	366	45	393	Chitinase domain-containing protein 1 OS=Mus musculus OX=10090 GN=Chid1 PE=1 SV=1
1.18e-66	49	366	45	393	Chitinase domain-containing protein 1 OS=Rattus norvegicus OX=10116 GN=Chid1 PE=2 SV=2
1.18e-66	49	366	45	393	Chitinase domain-containing protein 1 OS=Pongo abelii OX=9601 GN=CHID1 PE=2 SV=1
1.67e-66	51	366	47	393	Chitinase domain-containing protein 1 OS=Bos taurus OX=9913 GN=CHID1 PE=2 SV=1
3.31e-66	49	366	45	393	Chitinase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHID1 PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.001157	0.998814	CS pos: 28-29. Pr: 0.9132

TMHMM Annotations download full data without filtering help

Start	End
7	26