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CAZyme Information: GBF63454.1

You are here: Home > Sequence: GBF63454.1

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Trichophyton mentagrophytes
Lineage Ascomycota; Eurotiomycetes; ; Arthrodermataceae; Trichophyton; Trichophyton mentagrophytes
CAZyme ID GBF63454.1
CAZy Family GH3
CAZyme Description exo-alpha-sialidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
408 44596.93 9.8083
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_TmentagrophytesTIMM2789 7958 N/A 98 7860
Gene Location

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.18:1 3.2.1.-:1

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH33 56 380 7.2e-55 0.9181286549707602

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
271229 Sialidase 2.08e-84 48 398 2 361
sialidases/neuraminidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed beta-propeller fold. This hierarchy includes eubacterial, eukaryotic, and viral sialidases.
271234 Sialidase_non-viral 1.65e-59 57 398 10 339
Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases.
404074 BNR_2 2.47e-05 72 372 1 279
BNR repeat-like domain. This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
1.03e-218 5 408 2 409
1.25e-216 24 408 21 406
1.12e-200 4 408 13 424
9.71e-195 38 408 4 376
1.27e-175 10 408 4 403

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
1.07e-308 1 408 1 408
Chain A, Extracellular sialidase/neuraminidase [Trichophyton rubrum],7P1V_B Chain B, Extracellular sialidase/neuraminidase [Trichophyton rubrum],7P1V_C Chain C, Extracellular sialidase/neuraminidase [Trichophyton rubrum],7P1V_D Chain D, Extracellular sialidase/neuraminidase [Trichophyton rubrum]
2.83e-294 23 408 1 386
Chain A, Extracellular sialidase/neuraminidase [Trichophyton rubrum],7P1R_A Chain A, Extracellular sialidase/neuraminidase [Trichophyton rubrum],7P1R_B Chain B, Extracellular sialidase/neuraminidase [Trichophyton rubrum],7P1R_C Chain C, Extracellular sialidase/neuraminidase [Trichophyton rubrum],7P1R_D Chain D, Extracellular sialidase/neuraminidase [Trichophyton rubrum],7P1S_A Chain A, Extracellular sialidase/neuraminidase [Trichophyton rubrum],7P1S_B Chain B, Extracellular sialidase/neuraminidase [Trichophyton rubrum],7P1S_C Chain C, Extracellular sialidase/neuraminidase [Trichophyton rubrum],7P1S_D Chain D, Extracellular sialidase/neuraminidase [Trichophyton rubrum],7P1U_A Chain A, Extracellular sialidase/neuraminidase [Trichophyton rubrum],7P1U_B Chain B, Extracellular sialidase/neuraminidase [Trichophyton rubrum]
2.08e-218 24 408 1 386
The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural And Mechanistic Insights [Aspergillus fumigatus Af293],2XZI_B The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural And Mechanistic Insights [Aspergillus fumigatus Af293],2XZJ_A The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural And Mechanistic Insights [Aspergillus fumigatus Af293],2XZJ_B The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural And Mechanistic Insights [Aspergillus fumigatus Af293],2XZK_A The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural And Mechanistic Insights [Aspergillus fumigatus Af293],2XZK_B The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural And Mechanistic Insights [Aspergillus fumigatus Af293]
4.46e-217 24 408 37 422
Structural evaluation the Y358H mutant of the aspergillus fumigatus kdnase (sialidase) [Aspergillus fumigatus Af293],4M4N_B Structural evaluation the Y358H mutant of the aspergillus fumigatus kdnase (sialidase) [Aspergillus fumigatus Af293]
8.98e-217 24 408 37 422
Structural evaluation R171L mutant of the aspergillus fumigatus kdnase (sialidase) [Aspergillus fumigatus Af293],4M4V_B Structural evaluation R171L mutant of the aspergillus fumigatus kdnase (sialidase) [Aspergillus fumigatus Af293]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
1.29e-306 1 408 1 408
Exo-alpha-sialidase ARB_03431 OS=Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331 GN=ARB_03431 PE=1 SV=1
2.22e-217 24 408 21 406
Exo-alpha-sialidase OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=AFUA_4G13800 PE=1 SV=2
3.34e-15 60 377 202 527
Sialidase OS=Bacteroides fragilis (strain YCH46) OX=295405 GN=nanH PE=3 SV=2
1.61e-13 57 402 63 401
Sialidase OS=Micromonospora viridifaciens OX=1881 GN=nedA PE=1 SV=1
8.76e-08 40 230 329 587
Sialidase A OS=Streptococcus pneumoniae OX=1313 GN=nanA PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI CS Position
0.000309 0.999662 CS pos: 22-23. Pr: 0.9750

TMHMM  Annotations      help

There is no transmembrane helices in GBF63454.1.