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CAZyme Information: GAX95264.1
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Pythium insidiosum | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Oomycota; NA; ; Pythiaceae; Pythium; Pythium insidiosum | |||||||||||
| CAZyme ID | GAX95264.1 | |||||||||||
| CAZy Family | CBM47 | |||||||||||
| CAZyme Description | GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase [Source:UniProtKB/TrEMBL;Acc:A0A2D4BLV0] | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | ||||||||||||
Enzyme Prediction help
| EC | 2.4.1.131:1 |
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CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| 340835 | GT4_ALG11-like | 1.14e-170 | 37 | 465 | 1 | 399 | alpha-1,2-mannosyltransferase ALG11 and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. ALG11 in yeast is involved in adding the final 1,2-linked Man to the Man5GlcNAc2-PP-Dol synthesized on the cytosolic face of the ER. The deletion analysis of ALG11 was shown to block the early steps of core biosynthesis that takes place on the cytoplasmic face of the ER and lead to a defect in the assembly of lipid-linked oligosaccharides. |
| 215511 | PLN02949 | 9.23e-128 | 39 | 494 | 36 | 458 | transferase, transferring glycosyl groups |
| 406369 | ALG11_N | 2.05e-94 | 37 | 277 | 1 | 208 | ALG11 mannosyltransferase N-terminus. |
| 395425 | Glycos_transf_1 | 9.64e-23 | 303 | 456 | 1 | 142 | Glycosyl transferases group 1. Mutations in this domain of PIGA lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family. |
| 340834 | GT4_ALG2-like | 1.18e-21 | 236 | 456 | 133 | 362 | alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. A deficiency of this enzyme causes an abnormal accumulation of Man1GlcNAc2-PP-dolichol and Man2GlcNAc2-PP-dolichol, which is associated with a type of congenital disorders of glycosylation (CDG), designated CDG-Ii, in humans. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| 8.97e-195 | 12 | 498 | 20 | 491 | |
| 1.74e-148 | 12 | 494 | 14 | 483 | |
| 1.74e-148 | 12 | 494 | 14 | 483 | |
| 6.20e-106 | 37 | 492 | 63 | 489 | |
| 6.20e-106 | 37 | 492 | 63 | 489 |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 4.37e-106 | 37 | 492 | 63 | 489 | GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase OS=Homo sapiens OX=9606 GN=ALG11 PE=1 SV=2 |
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| 6.17e-106 | 38 | 492 | 64 | 489 | GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase OS=Mus musculus OX=10090 GN=Alg11 PE=2 SV=1 |
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| 1.73e-105 | 37 | 492 | 63 | 489 | GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase OS=Pongo abelii OX=9601 GN=ALG11 PE=2 SV=2 |
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| 1.87e-100 | 38 | 491 | 62 | 492 | GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase OS=Danio rerio OX=7955 GN=alg11 PE=2 SV=2 |
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| 2.75e-99 | 7 | 491 | 30 | 482 | GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase OS=Xenopus laevis OX=8355 GN=alg11 PE=2 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | CS Position |
|---|---|---|
| 1.000044 | 0.000001 |