CAZyme Information: FVEG_12117-t26_3-p1

Basic Information

• Species: Fusarium verticillioides
• Lineage: Ascomycota; Sordariomycetes; ; Nectriaceae; Fusarium; Fusarium verticillioides
• CAZyme ID: FVEG_12117-t26_3-p1
• CAZy Family: GH71
• CAZyme Description: trehalose 6-phosphate synthase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
665		74915.41	6.3170

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_Fverticillioides7600	16240	334819	371	15869

• Gene Location: location=CM000581.1:2498388-2500435(-)

Full Sequence      

MNQKFANKIIEIYKPGDIVIIHDYFLMLLPSMLRQRVPNMYISFFLHSPFPSSEFLRCLP
RRKEVLEGVLGSNLIGFQSYSYSRHFLSCCTRILGFPSDTLGIDAYGTRVQVGVFPIGID
AAKVESHAWTDAVTAKYNALRELYRGKKIIVGRDRLDSVRGVAQKLQAFERFLEMYPEWR
EKVVLIQVTSPTSVEAEKEDLEDDTKVATRVNELVMRINGMYGSLGFSPVQHYPQYLSQN
EYFALLRASDIGLITSVRDGMNTTSLEYIICQKEGNAPLILSEFSGTAHSLSDAIHINPW
DLSGVAEKINAALTMSEAKRQDMQSRLYKHVTEHNVQSWITKFIRKVYNVLGDSSSANST
PLLDRALLLTQYRSANKRLFMFDYDGTLTPIVREPSAAVPSERLIHTLDLLASDPKNAVW
IISGRDQDFLKQHLGNNRRLGFSAEHGSFMKHPGSDEWENLAEKFDMGWQAEVMEVFQKY
TDRVQGSFIERKRCALTWHYRLADPEQGIHMSRECHKELESTVGAKWDVEVMPGKANIEV
RPTFINKGEIAKRLITMYHTPGTESEDKSGHLEFALCMGDDFTDEDMFRSLNAASGPVLD
ANHVFTVTVGASTKVTLAKSHLLEPEDVIECVALLAGVQDVGERLGEVNLGALSAVEGHI
PSAER

Enzyme Prediction     

EC	3.1.3.12:1

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT20	1	347	1.6e-143	0.72

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
184712	PRK14501	0.0	2	636	120	724	putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional
340820	GT20_TPS	0.0	1	345	120	460	trehalose-6-phosphate synthase. Trehalose-6-Phosphate Synthase (TPS, EC 2.4.1.15) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain.
395781	Glyco_transf_20	1.92e-167	1	349	124	470	Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex,.
223457	OtsA	1.24e-148	1	350	133	480	Trehalose-6-phosphate synthase [Carbohydrate transport and metabolism].
215556	PLN03064	2.22e-142	2	588	218	807	alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QKD49547.1|GT20	0.0	1	665	219	883
CCT67493.1|GT20	0.0	1	665	219	883
QGI63541.1|GT20	0.0	1	665	219	883
QGI94423.1|GT20	0.0	1	665	219	883
QGI80816.1|GT20	0.0	1	665	219	883

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5DXF_A	1.61e-125	2	344	184	520	Structure of Candida albicans trehalose-6-phosphate phosphatase N-terminal domain [Candida albicans SC5314],5DXF_B Structure of Candida albicans trehalose-6-phosphate phosphatase N-terminal domain [Candida albicans SC5314]
5DXN_A	2.82e-118	360	635	3	269	Structure of Aspergillus fumigatus trehalose-6-phosphate phosphatase crystal form 2 [Aspergillus fumigatus Af293],5DXO_A Structure of Aspergillus fumigatus trehalose-6-phosphate phosphatase crystal form 3 [Aspergillus fumigatus Af293],5DXO_B Structure of Aspergillus fumigatus trehalose-6-phosphate phosphatase crystal form 3 [Aspergillus fumigatus Af293]
5DXL_A	4.94e-113	360	635	3	269	Structure of Aspergillus fumigatus trehalose-6-phosphate phosphatase crystal form 1 [Aspergillus fumigatus Af293]
5DXI_A	7.90e-97	360	638	5	300	Structure of C. albicans Trehalose-6-phosphate phosphatase C-terminal domain [Candida albicans SC5314],5DXI_B Structure of C. albicans Trehalose-6-phosphate phosphatase C-terminal domain [Candida albicans SC5314]
5HUV_A	4.39e-87	2	348	122	468	Structure of Candida albicans trehalose-6-phosphate synthase E341R/E346R in complex with UDP-glucose [Candida albicans SC5314],5HUV_B Structure of Candida albicans trehalose-6-phosphate synthase E341R/E346R in complex with UDP-glucose [Candida albicans SC5314]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P31688|TPS2_YEAST	8.99e-203	2	664	183	871	Trehalose-phosphatase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=TPS2 PE=1 SV=3
sp|Q9P4D3|TPS2_ZYGRO	9.25e-195	2	664	189	878	Trehalose-phosphatase OS=Zygosaccharomyces rouxii OX=4956 GN=TPS2 PE=1 SV=1
sp|P78875|TPP1_SCHPO	9.48e-194	1	636	196	813	Trehalose-phosphatase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=tpp1 PE=1 SV=2
sp|O14145|TPS2_SCHPO	1.50e-154	2	630	204	844	Trehalose-phosphatase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=tps2 PE=3 SV=1
sp|Q54K57|TPSA_DICDI	7.34e-150	2	628	132	727	Alpha,alpha-trehalose-phosphate synthase [UDP-forming] A OS=Dictyostelium discoideum OX=44689 GN=tpsA PE=2 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000046	0.000000

TMHMM  Annotations     

There is no transmembrane helices in FVEG_12117-t26_3-p1.