CAZyme Information: FPRO_14650-t41_1-p1

Basic Information

• Species: Fusarium proliferatum
• Lineage: Ascomycota; Sordariomycetes; ; Nectriaceae; Fusarium; Fusarium proliferatum
• CAZyme ID: FPRO_14650-t41_1-p1
• CAZy Family: GT17
• CAZyme Description: related to sterol glucosyltransferase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
803	FJOF01000008|CGC6	86080.13	7.4996

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_FproliferatumET1	16509	1227346	366	16143

• Gene Location: location=FJOF01000008:2387188-2390119(+)

Full Sequence      

MSKSGSQSPPKGKEVQDTDNVLDIPWDAPPPYELHSSGSVLASTSRVNDYGKVDIEFSSL
QPDEVNRLLPPDKAQEIEPSGSFSTAAPSGPCPALNVVIQVVGSRGDVQPFIALGVALQR
YGHRVRLATHDTFTDFVRSSGLEFYPVGGDPEDLMAYMVKNPGLIPSMESLRGGDIGRKR
VMIHDMLRGFWSSCVKPDTVSNRPFVADAIIANPPSFAHVHCAQALGIPLHMMFTMPWTA
TRSFPHPLANIQSQNMDPRASNYLSYGVVDLMTWQGLGDVINAWRVKDLHLDPLAAAVGP
DIVGLMKVPYTYCWSPALVPKPSDWGESIDICGFFMRDEPAYTPPQDLADFLARGPPPVY
IGFGSIVIDDPTALTNIIKESCRVAGARVIISRGWSKLGGNDPSTDSVFYLGDCPHEWLF
KRVAAVVHHGGAGTTACGLVNGRPTTIVPFFGDQPFWGSVVASNGAGPSPIAYKGISVDK
LSSAIKFCLSPEAQAAANRIATQMREESGVNTAVNSFHRHLPVANLICELIPHNAAKWQY
VGKSKKGDKGHIRLSNAALKVLLDAKKAKLADFEPLRPKEYLVENERWDPVTAGASSVLG
TMTDFTSALGGAFIDPFKDVKRVRPDGTRRSAGTATAVASGKALQGMTTAVVKGSLVDVP
LAFAEGFRNTPRLYGEKVADYGPVTDWKSGGTVAAKNFGFGFYEGLTDIVTKPMKGAKEE
GALGFFKGVGKGSLNMVAKPGSATFGLLAYPAQGIYKSIQSMKTNKARDAVTAGRVESLS
DGEQGAASPDAPQVVERFQELIG

Enzyme Prediction     

EC	2.4.1.173:23	2.4.1.-:3

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT1	115	519	5.5e-51	0.981675392670157

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
340817	GT1_Gtf-like	1.22e-80	95	520	1	404	UDP-glycosyltransferases and similar proteins. This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.
224732	YjiC	9.11e-40	103	519	10	397	UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism].
397255	Glyco_transf_28	6.89e-23	97	245	1	139	Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities.
273616	MGT	3.19e-07	106	509	7	378	glycosyltransferase, MGT family. This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance]
227376	MRS6	0.004	692	759	2346	2413	Vacuolar protein sorting-associated protein [Intracellular trafficking and secretion].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CCT75037.1|GT1	0.0	1	803	1	803
QGI70427.1|GT1	0.0	1	803	1	808
QGI87785.1|GT1	0.0	1	803	1	808
QGJ01316.1|GT1	0.0	1	803	1	808
QKD60288.1|GT1	0.0	1	801	1	801

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5XVM_A	1.60e-74	102	527	27	445	Sterol 3-beta-glucosyltransferase (ugt51) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [Saccharomyces cerevisiae S288C],5XVM_B Sterol 3-beta-glucosyltransferase (ugt51) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [Saccharomyces cerevisiae S288C]
5GL5_A	2.69e-74	102	527	47	465	Sterol 3-beta-glucosyltransferase (ugt51) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c): UDPG complex [Saccharomyces cerevisiae S288C],5GL5_B Sterol 3-beta-glucosyltransferase (ugt51) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c): UDPG complex [Saccharomyces cerevisiae S288C]
1IIR_A	6.34e-35	95	513	1	391	Crystal Structure of UDP-glucosyltransferase GtfB [Amycolatopsis orientalis]
3H4I_A	9.65e-32	95	507	1	368	Chimeric Glycosyltransferase for the generation of novel natural products [Amycolatopsis orientalis],3H4T_A Chimeric Glycosyltransferase for the generation of novel natural products - GtfAH1 in complex with UDP-2F-Glc [Amycolatopsis orientalis]
1RRV_A	3.12e-26	95	501	1	380	X-ray crystal structure of TDP-vancosaminyltransferase GtfD as a complex with TDP and the natural substrate, desvancosaminyl vancomycin. [Amycolatopsis orientalis],1RRV_B X-ray crystal structure of TDP-vancosaminyltransferase GtfD as a complex with TDP and the natural substrate, desvancosaminyl vancomycin. [Amycolatopsis orientalis]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q9XIG1|U80B1_ARATH	1.29e-136	93	522	154	575	Sterol 3-beta-glucosyltransferase UGT80B1 OS=Arabidopsis thaliana OX=3702 GN=UGT80B1 PE=1 SV=1
sp|Q9M8Z7|U80A2_ARATH	5.94e-134	93	524	191	613	Sterol 3-beta-glucosyltransferase UGT80A2 OS=Arabidopsis thaliana OX=3702 GN=UGT80A2 PE=1 SV=1
sp|Q54IL5|UGT52_DICDI	2.11e-82	67	536	1137	1624	UDP-sugar-dependent glycosyltransferase 52 OS=Dictyostelium discoideum OX=44689 GN=ugt52 PE=2 SV=1
sp|Q6C8M8|ATG26_YARLI	8.63e-82	64	529	967	1421	Sterol 3-beta-glucosyltransferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) OX=284591 GN=ATG26 PE=3 SV=3
sp|A7ERM5|ATG26_SCLS1	1.04e-79	78	542	926	1387	Sterol 3-beta-glucosyltransferase OS=Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) OX=665079 GN=atg26 PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000053	0.000000

TMHMM  Annotations     

There is no transmembrane helices in FPRO_14650-t41_1-p1.