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CAZyme Information: FPRO_14073-t41_1-p1

You are here: Home > Sequence: FPRO_14073-t41_1-p1

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Fusarium proliferatum
Lineage Ascomycota; Sordariomycetes; ; Nectriaceae; Fusarium; Fusarium proliferatum
CAZyme ID FPRO_14073-t41_1-p1
CAZy Family GH78
CAZyme Description related to adenine phosphoribosyltransferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1116 123606.00 7.5437
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_FproliferatumET1 16509 1227346 366 16143
Gene Location

Full Sequence      Download help

Enzyme Prediction      help

EC 1.1.3.-:1

CAZyme Signature Domains help

Family Start End Evalue family coverage
AA7 290 524 2.4e-41 0.4737991266375546

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
235028 PRK02304 4.31e-31 923 1114 1 174
adenine phosphoribosyltransferase; Provisional
223577 Apt 1.54e-22 937 1097 17 164
Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein [Nucleotide transport and metabolism].
177930 PLN02293 1.36e-18 924 1097 13 173
adenine phosphoribosyltransferase
396238 FAD_binding_4 1.17e-17 300 429 1 130
FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidizes the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.
206754 PRTases_typeI 7.55e-17 961 1096 1 118
Phosphoribosyl transferase (PRT)-type I domain. Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
2.06e-12 300 717 63 482
1.12e-11 286 720 60 491
5.96e-11 294 720 58 490
1.02e-10 300 483 61 229
1.04e-10 294 720 58 490

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
2.96e-17 299 481 38 203
Crystal structure of 6-hydoxy-D-nicotine oxidase from Arthrobacter nicotinovorans. Crystal Form 3 (P1) [Paenarthrobacter nicotinovorans],2BVF_B Crystal structure of 6-hydoxy-D-nicotine oxidase from Arthrobacter nicotinovorans. Crystal Form 3 (P1) [Paenarthrobacter nicotinovorans],2BVG_A Crystal structure of 6-hydoxy-D-nicotine oxidase from Arthrobacter nicotinovorans. Crystal Form 1 (P21) [Paenarthrobacter nicotinovorans],2BVG_B Crystal structure of 6-hydoxy-D-nicotine oxidase from Arthrobacter nicotinovorans. Crystal Form 1 (P21) [Paenarthrobacter nicotinovorans],2BVG_C Crystal structure of 6-hydoxy-D-nicotine oxidase from Arthrobacter nicotinovorans. Crystal Form 1 (P21) [Paenarthrobacter nicotinovorans],2BVG_D Crystal structure of 6-hydoxy-D-nicotine oxidase from Arthrobacter nicotinovorans. Crystal Form 1 (P21) [Paenarthrobacter nicotinovorans],2BVH_A Crystal structure of 6-hydoxy-D-nicotine oxidase from Arthrobacter nicotinovorans. Crystal Form 2 (P21) [Paenarthrobacter nicotinovorans],2BVH_B Crystal structure of 6-hydoxy-D-nicotine oxidase from Arthrobacter nicotinovorans. Crystal Form 2 (P21) [Paenarthrobacter nicotinovorans],2BVH_C Crystal structure of 6-hydoxy-D-nicotine oxidase from Arthrobacter nicotinovorans. Crystal Form 2 (P21) [Paenarthrobacter nicotinovorans],2BVH_D Crystal structure of 6-hydoxy-D-nicotine oxidase from Arthrobacter nicotinovorans. Crystal Form 2 (P21) [Paenarthrobacter nicotinovorans]
9.97e-16 922 1114 3 179
Crystal structure of an APRT from Yersinia pseudotuberculosis in complex with AMP. [Yersinia pseudotuberculosis IP 32953]
1.15e-15 922 1114 9 185
Crystal structure of adenine phosphoribosyltransferase from Yersinia pseudotuberculosis. [Yersinia pseudotuberculosis IP 32953],5Y07_A Crystal structure of adenine phosphoribosyltransferase from Yersinia pseudotuberculosis with PRPP. [Yersinia pseudotuberculosis IP 32953],5Y07_B Crystal structure of adenine phosphoribosyltransferase from Yersinia pseudotuberculosis with PRPP. [Yersinia pseudotuberculosis IP 32953],5Y4A_A Cadmium directed assembly of adenine phosphoribosyltransferase from Yersinia pseudotuberculosis. [Yersinia pseudotuberculosis IP 32953],5Y4A_B Cadmium directed assembly of adenine phosphoribosyltransferase from Yersinia pseudotuberculosis. [Yersinia pseudotuberculosis IP 32953],5ZC7_A Crystal structure of APRT from Y. pseudotuberculosis with bound adenine (P63 space group). [Yersinia pseudotuberculosis IP 32953],5ZC7_B Crystal structure of APRT from Y. pseudotuberculosis with bound adenine (P63 space group). [Yersinia pseudotuberculosis IP 32953],5ZMI_A Crystal structure of APRT from Y. pseudotuberculosis in complex with adenine. [Yersinia pseudotuberculosis IP 32953],5ZNQ_A Crystal structure of APRT from Y. pseudotuberculosis with bound adenine (P21 space group). [Yersinia pseudotuberculosis IP 32953],5ZNQ_B Crystal structure of APRT from Y. pseudotuberculosis with bound adenine (P21 space group). [Yersinia pseudotuberculosis IP 32953],5ZOC_A Crystal structure of APRT from Y. pseudotuberculosis with bound adenine (C2 space group). [Yersinia pseudotuberculosis IP 32953]
2.62e-14 922 1084 12 163
Crystal structure of project JW0458 from Escherichia coli [Escherichia coli K-12],2DY0_B Crystal structure of project JW0458 from Escherichia coli [Escherichia coli K-12]
5.38e-14 920 1097 20 184
Crystal structure of adenine phosphoribosyltransferase from Thermoanaerobacter pseudethanolicus ATCC 33223, NYSGRC Target 029700. [Thermoanaerobacter pseudethanolicus ATCC 33223],4LZA_B Crystal structure of adenine phosphoribosyltransferase from Thermoanaerobacter pseudethanolicus ATCC 33223, NYSGRC Target 029700. [Thermoanaerobacter pseudethanolicus ATCC 33223]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
8.12e-20 927 1097 2 159
Adenine phosphoribosyltransferase OS=Kosmotoga olearia (strain ATCC BAA-1733 / DSM 21960 / TBF 19.5.1) OX=521045 GN=apt PE=3 SV=1
7.42e-19 927 1102 4 166
Adenine phosphoribosyltransferase OS=Roseiflexus castenholzii (strain DSM 13941 / HLO8) OX=383372 GN=apt PE=3 SV=1
2.20e-17 927 1102 4 166
Adenine phosphoribosyltransferase OS=Roseiflexus sp. (strain RS-1) OX=357808 GN=apt PE=3 SV=1
4.08e-17 927 1114 2 171
Adenine phosphoribosyltransferase OS=Clostridium novyi (strain NT) OX=386415 GN=apt PE=3 SV=1
1.36e-16 927 1097 2 160
Adenine phosphoribosyltransferase OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=apt PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI CS Position
1.000072 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in FPRO_14073-t41_1-p1.