CAZyme Information: FPRO_06247-t41_1-p1

Basic Information

• Species: Fusarium proliferatum
• Lineage: Ascomycota; Sordariomycetes; ; Nectriaceae; Fusarium; Fusarium proliferatum
• CAZyme ID: FPRO_06247-t41_1-p1
• CAZy Family: CE5
• CAZyme Description: related to class I alpha-mannosidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
979		109288.15	4.5513

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_FproliferatumET1	16509	1227346	366	16143

• Gene Location: location=FJOF01000003:2457463-2460507(+)

Full Sequence      

MLPLRRRGRFYAIVAVVMVFLLYRFMQNSWSQSPHFETVKQPSQPASDPVQGSKEAFEPP
VVPPPVQLPDSEQDSNAANKPKPAVPQDGPALPEKVSEKVDTPAEEKPVADEPISVGDAA
LPDDKKEEHKQPAEQSAPQIPDVHFKDPPKQADNPDIPDVNVDGSKVHWTKPKENFPIPP
ESIRPVPTGTAPSINRIQFDFQPEDVQTSTTRLDRLKRVKAEIERAWTGYRKFAFPHDEL
KPASMKYRDTFCGWGATLIDSLDTLWIAGMKEEFDEAAKAVANVDFTYSERNDIPVFETT
IRYLGGLIAAYDVSGGSSGQYKILLDKAVELAEVLMGVFDTPNRMPLLYYRWHEPYASQP
HRASTVGIAELGTLSMEFTRLAQLTGTNKYYDAVDRITDALIEMQAAGTDIPGLFPERID
ASGCNRTATTRTESLSQEAREQVNSADLTKEPEGFDPTKLGGDVASPAQLPQADSRWEDK
LQRRDVPVDTDEATKAGDQTPARPGPQQAPPLAADGSSADWDCKPQGLVSSSPNYGHYHM
GGAQDSAYEYFPKQYLLLNGLEPKYRPLYENTIDAINEWLLYRPMIKDDGWDVFFTGKLT
TSSRGDSEWLKTYDMAHLACFVGGMYGLGGKIFGRDGDIDKAKKLTDGCVWAYQSTVTGI
MPEYAHLVACPALEKCAFSEESWYEDLDPNREWRDSEFRKWSDGEAQRKLAEGAAPAAAQ
QNKPDDSNKGPEPVVNPPKVVKRAGIPMPELDRSMEEDDSEFGSTLPDSLKQKIGLNKDG
SENTEAEKAHPGKTDSEKAKPAPVELENQPAAVQDTTEKTIAPKPVTVDSFDAVRNAEQV
AASDDVPLERPATHEEYVKSRIQREKLPPGYTDIINRNYILRPEAIESVWYMYRITGDTT
WMDKGWKMFQATIAATRTEFANSAIEDVMGTENNLKDEMESFWISETLKYYYLLFSEPNV
ISLDEWVLNTEAHPFKRST

Enzyme Prediction     

EC	3.2.1.113:7

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH47	223	977	9.9e-169	0.9955156950672646

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
396217	Glyco_hydro_47	1.62e-167	224	977	3	453	Glycosyl hydrolase family 47. Members of this family are alpha-mannosidases that catalyze the hydrolysis of the terminal 1,2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2).
240427	PTZ00470	2.36e-78	173	977	27	518	glycoside hydrolase family 47 protein; Provisional
237082	PRK12373	0.004	75	159	244	323	NADH-quinone oxidoreductase subunit E.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QKD49719.1|GH47	0.0	1	979	1	979
QGI63378.1|GH47	0.0	1	979	1	979
QGI94260.1|GH47	0.0	1	979	1	979
QGI80656.1|GH47	0.0	1	979	1	979
CCT67337.1|GH47	0.0	1	979	1	979

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5KIJ_A	2.49e-33	215	398	5	181	Crystal structure of the class I human endoplasmic reticulum 1,2-alpha-mannosidase and Man9GlcNAc2-PA complex [Homo sapiens]
5KK7_A	2.61e-33	215	398	5	181	Crystal structure of the class I human endoplasmic reticulum 1,2-alpha-mannosidase T688A mutant and Thio-disaccharide substrate analog complex [Homo sapiens],5KK7_B Crystal structure of the class I human endoplasmic reticulum 1,2-alpha-mannosidase T688A mutant and Thio-disaccharide substrate analog complex [Homo sapiens]
1FMI_A	2.74e-33	215	398	10	186	Crystal Structure Of Human Class I Alpha1,2-Mannosidase [Homo sapiens]
1FO2_A	2.82e-33	215	398	10	186	Crystal Structure Of Human Class I Alpha1,2-Mannosidase In Complex With 1-Deoxymannojirimycin [Homo sapiens],1FO3_A Crystal Structure Of Human Class I Alpha1,2-Mannosidase In Complex With Kifunensine [Homo sapiens]
1X9D_A	8.01e-33	215	398	88	264	Crystal Structure Of Human Class I alpha-1,2-Mannosidase In Complex With Thio-Disaccharide Substrate Analogue [Homo sapiens]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|B2GUY0|MA1B1_RAT	2.20e-33	214	398	206	383	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase OS=Rattus norvegicus OX=10116 GN=Man1b1 PE=2 SV=2
sp|A2AJ15|MA1B1_MOUSE	1.64e-32	214	398	207	384	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase OS=Mus musculus OX=10090 GN=Man1b1 PE=1 SV=1
sp|A1D1W1|MNS1B_NEOFI	2.34e-32	219	663	36	367	Probable mannosyl-oligosaccharide alpha-1,2-mannosidase 1B OS=Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) OX=331117 GN=mns1B PE=3 SV=1
sp|B0XMT4|MNS1B_ASPFC	2.34e-32	203	663	20	367	Probable mannosyl-oligosaccharide alpha-1,2-mannosidase 1B OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) OX=451804 GN=mns1B PE=3 SV=1
sp|Q4WRZ5|MNS1B_ASPFU	2.34e-32	203	663	20	367	Probable mannosyl-oligosaccharide alpha-1,2-mannosidase 1B OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=mns1B PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000019	0.000001

TMHMM  Annotations     

Start	End
7	26