CAZyme Information: FPRO_05373-t41_1-p1

Basic Information

• Species: Fusarium proliferatum
• Lineage: Ascomycota; Sordariomycetes; ; Nectriaceae; Fusarium; Fusarium proliferatum
• CAZyme ID: FPRO_05373-t41_1-p1
• CAZy Family: CE12
• CAZyme Description: probable D-lactate dehydrogenase (cytochrome)

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
531	FJOF01000004|CGC7	57946.35	5.8355

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_FproliferatumET1	16509	1227346	366	16143

• Gene Location: location=FJOF01000004:3651473-3653142(+)

Full Sequence      

MADKKPRPKTDLDLTGLYILGLVALAVSTAGAQSTSSHPTKRQPSSTQSLLGAPKIQHDL
SASNIEGACKEFAAILGPENVSTERVDLVTHSGSDYQSYAWTEESAILSQVILYPETTEQ
VSELMKVCFQRRLPVTPYSGGTSIEGQYIPHLQGICIDFGRMNNIVELNKYDLDCVVQPG
MGWMDLNEELAAHGLFFPPDPGPGAMIGGMVGTGCSGTNAAAYGTMKDWVLSLTVVLADG
TIIKTRQRARKSSAGYDLTRTFIGSEGTLGLVTEATLKLAVKPPCEAVAVCTFPTLRDAA
SAVREVLSNGIQVAAVEILDEVQMKSINDSALTRLKWKEEPTLFFKFTGSDEFIVDHLAK
QVGSITKQNRSTAYTFASDETERNELWSARKNALWSMLAMRKSPSDKVWTTDVAVPLSRL
PDIIEFAKEDIQKSGLLGSIVGHVGDGNFHTLLLFPEEKRHIAEEIVHRMVDKAIEMKGT
ATGEHGVGLVKRDYLEKELGKEAVDTMRSMKNAFDPLCILNCDKVIRMKVA

Enzyme Prediction     

No EC number prediction in FPRO_05373-t41_1-p1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
AA7	102	307	5e-24	0.42358078602620086

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
178402	PLN02805	1.00e-151	71	526	101	549	D-lactate dehydrogenase [cytochrome]
223354	GlcD	7.84e-117	71	527	1	457	FAD/FMN-containing dehydrogenase [Energy production and conversion].
273050	glcD	7.92e-106	112	521	1	410	glycolate oxidase, subunit GlcD. This protein, the glycolate oxidase GlcD subunit, is similar in sequence to that of several D-lactate dehydrogenases, including that of E. coli. The glycolate oxidase has been found to have some D-lactate dehydrogenase activity. [Energy metabolism, Other]
397178	FAD-oxidase_C	3.30e-67	282	525	1	248	FAD linked oxidases, C-terminal domain. This domain has a ferredoxin-like fold.
183043	PRK11230	8.36e-57	89	526	34	472	glycolate oxidase subunit GlcD; Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QSZ31245.1|GT31	1.86e-108	108	482	547	905
QGA13141.1|AA4	1.88e-14	60	298	39	284
VBB76857.1|AA4	1.11e-13	54	298	55	317
QGA20504.1|AA4	1.43e-13	68	303	63	313
AEO67281.1|AA4	1.89e-13	54	303	51	316

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6LPN_A	1.95e-43	36	526	4	471	Chain A, D-2-hydroxyglutarate dehydrogenase, mitochondrial [Homo sapiens],6LPN_B Chain B, D-2-hydroxyglutarate dehydrogenase, mitochondrial [Homo sapiens],6LPP_A Chain A, D-2-hydroxyglutarate dehydrogenase, mitochondrial [Homo sapiens],6LPP_B Chain B, D-2-hydroxyglutarate dehydrogenase, mitochondrial [Homo sapiens],6LPQ_A Chain A, D-2-hydroxyglutarate dehydrogenase, mitochondrial [Homo sapiens],6LPQ_B Chain B, D-2-hydroxyglutarate dehydrogenase, mitochondrial [Homo sapiens],6LPT_A Chain A, D-2-hydroxyglutarate dehydrogenase, mitochondrial [Homo sapiens],6LPT_B Chain B, D-2-hydroxyglutarate dehydrogenase, mitochondrial [Homo sapiens],6LPU_A Chain A, D-2-hydroxyglutarate dehydrogenase, mitochondrial [Homo sapiens],6LPU_B Chain B, D-2-hydroxyglutarate dehydrogenase, mitochondrial [Homo sapiens],6LPX_A Chain A, D-2-hydroxyglutarate dehydrogenase, mitochondrial [Homo sapiens],6LPX_B Chain B, D-2-hydroxyglutarate dehydrogenase, mitochondrial [Homo sapiens]
3PM9_A	3.62e-39	72	526	21	476	Chain A, Putative oxidoreductase [Rhodopseudomonas palustris],3PM9_B Chain B, Putative oxidoreductase [Rhodopseudomonas palustris],3PM9_C Chain C, Putative oxidoreductase [Rhodopseudomonas palustris],3PM9_D Chain D, Putative oxidoreductase [Rhodopseudomonas palustris],3PM9_E Chain E, Putative oxidoreductase [Rhodopseudomonas palustris],3PM9_F Chain F, Putative oxidoreductase [Rhodopseudomonas palustris]
2UUU_A	5.80e-24	70	526	96	584	alkyldihydroxyacetonephosphate synthase in P212121 [Dictyostelium discoideum],2UUU_B alkyldihydroxyacetonephosphate synthase in P212121 [Dictyostelium discoideum],2UUU_C alkyldihydroxyacetonephosphate synthase in P212121 [Dictyostelium discoideum],2UUU_D alkyldihydroxyacetonephosphate synthase in P212121 [Dictyostelium discoideum],2UUV_A alkyldihydroxyacetonephosphate synthase in P1 [Dictyostelium discoideum],2UUV_B alkyldihydroxyacetonephosphate synthase in P1 [Dictyostelium discoideum],2UUV_C alkyldihydroxyacetonephosphate synthase in P1 [Dictyostelium discoideum],2UUV_D alkyldihydroxyacetonephosphate synthase in P1 [Dictyostelium discoideum]
4BCA_A	7.03e-22	108	516	205	648	MAMMALIAN ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE: Tyr578Phe mutant [Cavia porcellus],4BCA_B MAMMALIAN ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE: Tyr578Phe mutant [Cavia porcellus],4BCA_C MAMMALIAN ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE: Tyr578Phe mutant [Cavia porcellus],4BCA_D MAMMALIAN ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE: Tyr578Phe mutant [Cavia porcellus]
4BC7_A	9.35e-22	108	516	205	648	MAMMALIAN ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE: Arg419His mutant [Cavia porcellus],4BC7_B MAMMALIAN ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE: Arg419His mutant [Cavia porcellus],4BC7_C MAMMALIAN ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE: Arg419His mutant [Cavia porcellus],4BC7_D MAMMALIAN ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE: Arg419His mutant [Cavia porcellus]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q12627|DLD1_KLULA	3.71e-148	78	528	115	569	D-lactate dehydrogenase [cytochrome], mitochondrial OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) OX=284590 GN=DLD1 PE=3 SV=2
sp|P32891|DLD1_YEAST	5.93e-147	49	527	93	576	D-lactate dehydrogenase [cytochrome] 1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=DLD1 PE=1 SV=2
sp|Q94AX4|DLD_ARATH	5.53e-128	79	526	120	561	D-lactate dehydrogenase [cytochrome], mitochondrial OS=Arabidopsis thaliana OX=3702 GN=DLD PE=1 SV=1
sp|Q7TNG8|LDHD_MOUSE	6.83e-110	74	526	37	484	Probable D-lactate dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Ldhd PE=1 SV=1
sp|Q86WU2|LDHD_HUMAN	9.45e-107	69	526	28	507	Probable D-lactate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=LDHD PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.071345	0.928608	CS pos: 32-33. Pr: 0.8775

TMHMM  Annotations     

There is no transmembrane helices in FPRO_05373-t41_1-p1.