CAZyme Information: FOYG_15563-t42_1-p1

Basic Information

• Species: Fusarium oxysporum
• Lineage: Ascomycota; Sordariomycetes; ; Nectriaceae; Fusarium; Fusarium oxysporum
• CAZyme ID: FOYG_15563-t42_1-p1
• CAZy Family: GT31
• CAZyme Description: chitin synthase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
978		110351.39	7.1433

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_FoxysporumNRRL32931	17642	660029	362	17280

• Gene Location: location=JH717849.1:923707-926765(+)

Full Sequence      

MGFNPQGQGNGPNYDAPREMQDLPAGQAYHFRESDETAAARVSPVSNPYEPDYDQLSPPP
PLGAQRPVPEQNESSRDLLHSSYQGSVGHNSFDGHSFGHNSYGPGAFGHYPADQHGRMPG
SPGYEYPEPEYDVEASRLAESRLSVMHRAPTMQDWGQNGEALSVPDFAHGRPDSTYQEFD
VDESWMMRQQQNQLAGGLGRSKTRKVKLVQGSVLSIDYPVPSAIKNAVEPRYRSGPGSME
EEFTKMRYTAATCDPNDFTLRNGFNLRPKMYNRHTELLIAITYYNEDKVLLARTLHGTMQ
NIRDIVNLKRSKFWNKGGPAWQKIVVCLVFDGIDKVDKNVFDVLATVGIYQDGVLKKDVN
GKETVAHIFEYTSQVSVTPDQQLVRPDPDKPHRNLPPVQFIFCLKQKNSKKINSHRWLFN
AFGRILNPEVAILIDAGTKPGPRALLSLWEGFYNDRDLGGACGEIHVMLGKGGKMLLNPL
VAVQNFEYKISNVLDKPLESAFGYVSVLPGAFSAYRFRAIMGRPLEQYFHGDHTLSKSLG
KKGIDGMNIFKKNMFLAEDRILCFELVAKASQKWHLSYIKASKGETDVPEGAAEFIGQRR
RWLNGSFAMSLYSLMHFGRMYGSGHNLIRLFFLHIQFVYNLVNVLFSWFSLAAFYLTTTI
IMKLVGTPQVLSEYHGWPFGDTATPIVNVLIKYIYIAFLVLQFVLALGNRPKGAQYTYVL
SFMVFGLIQLYLLVLTGYLVYRAFTGTPIEEQISFESGKAFFDSFFGGDTGVAGLIIIAL
FTIYGLNYIASFLYLDPWHMFHSFPQYLVLMSTYINILMVYAFNNWHDVSWGTKGSDTAE
ALPSAMIVKDEKGKEAVVEEIEQEQEDIDSKFEKVVWRALAPMSEMAEEKPEKKDVEDSY
KSFRTGLVILWLLCNIVLIVVVTTDDFITLGVSKAADVRTPTYFRVLLYSTAVLSIVRFF
GFLWFIGRTGIMCCIARR

Enzyme Prediction     

EC	2.4.1.16:26	2.4.1.16:26

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	283	452	2.5e-68	0.9938650306748467
GT2	429	700	1e-21	0.49335863377609107

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
396286	Chitin_synth_1	9.97e-96	283	452	1	163	Chitin synthase. This region is found commonly in chitin synthases classes I, II and III. Chitin a linear homopolymer of GlcNAc residues, it is an important component of the cell wall of fungi and is synthesized on the cytoplasmic surface of the cell membrane by membrane bound chitin synthases.
133033	Chitin_synth_C	1.79e-89	279	608	1	243	C-terminal domain of Chitin Synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin. Chitin synthase, also called UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyltransferase, catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of GlcNAc residues formed by covalent beta-1,4 linkages. Chitin is an important component of the cell wall of fungi and bacteria and it is synthesized on the cytoplasmic surface of the cell membrane by membrane bound chitin synthases. Studies with fungi have revealed that most of them contain more than one chitin synthase gene. At least five subclasses of chitin synthases have been identified.
400626	Chitin_synth_1N	1.00e-33	205	282	1	70	Chitin synthase N-terminal. This is the N-terminal domain of Chitin synthase (pfam01644).
224136	BcsA	1.21e-24	401	745	115	412	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility].
133045	CESA_like	8.30e-16	400	521	55	167	CESA_like is the cellulose synthase superfamily. The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QKD62621.1|GT2	0.0	1	978	1	978
AAT77183.1|GT2	0.0	1	978	1	978
ACY08040.1|GT2	0.0	1	978	1	978
CCT75589.1|GT2	0.0	1	978	1	978
QGI88197.1|GT2	0.0	1	978	1	987

PDB Hits     

FOYG_15563-t42_1-p1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q92197|CHSC_ASPFU	0.0	174	978	98	893	Chitin synthase C OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=chsC PE=3 SV=2
sp|P30602|CHS3_EXODE	0.0	55	931	9	861	Chitin synthase 3 OS=Exophiala dermatitidis OX=5970 GN=CHS3 PE=3 SV=2
sp|P29070|CHS1_NEUCR	0.0	88	978	21	917	Chitin synthase 1 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=chs-1 PE=3 SV=2
sp|Q00757|CHSB_EMENI	0.0	161	978	106	916	Chitin synthase B OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=chsB PE=2 SV=2
sp|P54267|CHSG_ASPFU	0.0	161	978	102	911	Chitin synthase G OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=chsG PE=2 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000060	0.000000

TMHMM  Annotations     

Start	End
635	657
686	708
718	740
772	794
804	826
907	929
944	966