CAZyme Information: FOXG_08057-t26_1-p1

Basic Information

• Species: Fusarium oxysporum
• Lineage: Ascomycota; Sordariomycetes; ; Nectriaceae; Fusarium; Fusarium oxysporum
• CAZyme ID: FOXG_08057-t26_1-p1
• CAZy Family: GH12
• CAZyme Description: mannosyl-oligosaccharide alpha-1,2-mannosidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
979	CM000592.1|CGC23	109360.39	4.5799

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_Foxysporum4287	21354	426428	429	20925

• Gene Location: location=CM000592.1:1956623-1959666(-)

Full Sequence      

MLPLRRRGRFYAIVAVVMVFLLYRFMQNSWSQSPHFETVKQPSQPASDPVQGSKEAFEPP
VVPPPVQLPDSEQDSNAANKPKPAVPQDGPTLPEKVAEKVDTPAEEKPVVDKPIPVGDAA
LPDDKKEEHKKPAEQSAPQIPDVHFKDPPKQADNPDIPDVNVDGSKVHWTKPKENFPIPP
ESIRPVPTGTAPSINRIQFDFQPEDVQTSTTRLDRLKRVKAEIERAWTGYRKFAFPHDEL
KPASMKYRDTFCGWGATLIDSLDTLWIAGMQEEFDEAAKAVANVDFTYSERNDIPVFETT
IRYLGGLIAAYDVSGGPSGQYKILLDKAVELAEVLMGVFDTPNRMPLLYYRWHEPYASQP
HRASTVGIAELGTLSMEFTRLAQLTGTNKYYDAVDRITDALIEMQAAGTDIPGLFPERID
ASGCNRTAATRTESLSQEAREQVNSADLTKEPEGFDPTKLGGDVASPAQLPQADSRWEDK
LQRRDVPVDTDEATNAGDQTPARPGAQQAPPLTADGSSADWDCKPQGLVSSSPSYGHFHM
GGAQDSAYEYFPKQYLLLNGLEPKYRPLYENTIDAINEWLLYRPMIKDDGWDVFFTGKLT
TSSRGDSEWTKTYDMAHLACFVGGMYGLGGKIFGRDGDIDKAKKLTDGCVWAYQSTATGI
MPEYAHLVACPALEKCAFSEESWYEDLDPNREWRDSEFRKWSDGEAQRKLAEGAAPAAAQ
QNKPDNSNKGPEPVVNPPKVVKRAGIPMPELDRSMEEDDSEFGSTLPDSLKQKIGLNKDG
SEKTEAEKADLGKTDSEKAKPAQVELENKPVAVQDTTEKTIAPKPVTVDSFDAVRNAEQV
AASDDVPLERPVTHEEYVKSRIQRERLPPGYTDIMNRNYILRPEAIESVWYMYRITGDTT
WMDKGWKMFQATIAATRTEFANSAIEDVTATENNLKDEMESFWISETLKYYYLLFSEPNV
ISLDEWVLNTEAHPFKRPT

Enzyme Prediction     

EC	3.2.1.113:7

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH47	223	977	4e-170	0.9955156950672646

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
396217	Glyco_hydro_47	6.50e-169	224	977	3	453	Glycosyl hydrolase family 47. Members of this family are alpha-mannosidases that catalyze the hydrolysis of the terminal 1,2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2).
240427	PTZ00470	1.26e-79	173	978	27	519	glycoside hydrolase family 47 protein; Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QKD49719.1|GH47	0.0	1	979	1	979
QGI63378.1|GH47	0.0	1	979	1	979
QGI94260.1|GH47	0.0	1	979	1	979
QGI80656.1|GH47	0.0	1	979	1	979
CCT67337.1|GH47	0.0	1	979	1	979

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5KIJ_A	8.18e-33	215	398	5	181	Crystal structure of the class I human endoplasmic reticulum 1,2-alpha-mannosidase and Man9GlcNAc2-PA complex [Homo sapiens]
5KK7_A	8.57e-33	215	398	5	181	Crystal structure of the class I human endoplasmic reticulum 1,2-alpha-mannosidase T688A mutant and Thio-disaccharide substrate analog complex [Homo sapiens],5KK7_B Crystal structure of the class I human endoplasmic reticulum 1,2-alpha-mannosidase T688A mutant and Thio-disaccharide substrate analog complex [Homo sapiens]
2RI8_A	8.58e-33	219	663	9	340	Penicillium citrinum alpha-1,2-mannosidase complex with glycerol [Penicillium citrinum],2RI8_B Penicillium citrinum alpha-1,2-mannosidase complex with glycerol [Penicillium citrinum],2RI9_A Penicillium citrinum alpha-1,2-mannosidase in complex with a substrate analog [Penicillium citrinum],2RI9_B Penicillium citrinum alpha-1,2-mannosidase in complex with a substrate analog [Penicillium citrinum]
1FMI_A	8.97e-33	215	398	10	186	Crystal Structure Of Human Class I Alpha1,2-Mannosidase [Homo sapiens]
1FO2_A	9.25e-33	215	398	10	186	Crystal Structure Of Human Class I Alpha1,2-Mannosidase In Complex With 1-Deoxymannojirimycin [Homo sapiens],1FO3_A Crystal Structure Of Human Class I Alpha1,2-Mannosidase In Complex With Kifunensine [Homo sapiens]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q4WRZ5|MNS1B_ASPFU	2.08e-34	203	663	20	367	Probable mannosyl-oligosaccharide alpha-1,2-mannosidase 1B OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=mns1B PE=3 SV=1
sp|B0XMT4|MNS1B_ASPFC	2.08e-34	203	663	20	367	Probable mannosyl-oligosaccharide alpha-1,2-mannosidase 1B OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) OX=451804 GN=mns1B PE=3 SV=1
sp|A1D1W1|MNS1B_NEOFI	2.80e-34	219	663	36	367	Probable mannosyl-oligosaccharide alpha-1,2-mannosidase 1B OS=Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) OX=331117 GN=mns1B PE=3 SV=1
sp|Q0D076|MNS1B_ASPTN	6.57e-33	215	663	39	374	Probable mannosyl-oligosaccharide alpha-1,2-mannosidase 1B OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) OX=341663 GN=mns1B PE=3 SV=1
sp|Q2ULB2|MNS1B_ASPOR	9.05e-33	192	663	18	375	Mannosyl-oligosaccharide alpha-1,2-mannosidase 1B OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) OX=510516 GN=mns1B PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000019	0.000001

TMHMM  Annotations     

Start	End
7	26