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CAZyme Information: FOC1_g10012728-t38_1-p1
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Fusarium oxysporum | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Ascomycota; Sordariomycetes; ; Nectriaceae; Fusarium; Fusarium oxysporum | |||||||||||
| CAZyme ID | FOC1_g10012728-t38_1-p1 | |||||||||||
| CAZy Family | GT1 | |||||||||||
| CAZyme Description | Chitin synthase 1 | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | ||||||||||||
Enzyme Prediction help
| EC | 2.4.1.16:26 | 2.4.1.16:26 |
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CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT2 | 213 | 381 | 2.8e-70 | 0.9938650306748467 |
| GT2 | 358 | 574 | 5e-23 | 0.3946869070208729 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| 396286 | Chitin_synth_1 | 7.44e-97 | 213 | 381 | 1 | 163 | Chitin synthase. This region is found commonly in chitin synthases classes I, II and III. Chitin a linear homopolymer of GlcNAc residues, it is an important component of the cell wall of fungi and is synthesized on the cytoplasmic surface of the cell membrane by membrane bound chitin synthases. |
| 133033 | Chitin_synth_C | 1.35e-92 | 209 | 538 | 1 | 244 | C-terminal domain of Chitin Synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin. Chitin synthase, also called UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyltransferase, catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of GlcNAc residues formed by covalent beta-1,4 linkages. Chitin is an important component of the cell wall of fungi and bacteria and it is synthesized on the cytoplasmic surface of the cell membrane by membrane bound chitin synthases. Studies with fungi have revealed that most of them contain more than one chitin synthase gene. At least five subclasses of chitin synthases have been identified. |
| 395127 | UQ_con | 5.89e-46 | 941 | 1076 | 1 | 139 | Ubiquitin-conjugating enzyme. Proteins destined for proteasome-mediated degradation may be ubiquitinated. Ubiquitination follows conjugation of ubiquitin to a conserved cysteine residue of UBC homologs. TSG101 is one of several UBC homologs that lacks this active site cysteine. |
| 227410 | COG5078 | 5.96e-42 | 934 | 1076 | 2 | 147 | Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]. |
| 238117 | UBCc | 1.17e-37 | 941 | 1073 | 3 | 138 | Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin protein ligase enzymes, E3. This pathway regulates many fundamental cellular processes. There are also other E2s which form thiol-ester linkages without the use of E3s as well as several UBC homologs (TSG101, Mms2, Croc-1 and similar proteins) which lack the active site cysteine essential for ubiquitination and appear to function in DNA repair pathways which were omitted from the scope of this CD. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| 0.0 | 1 | 1091 | 1 | 1126 | |
| 0.0 | 1 | 1091 | 1 | 1394 | |
| 0.0 | 1 | 860 | 1 | 893 | |
| 0.0 | 1 | 860 | 1 | 893 | |
| 0.0 | 1 | 860 | 1 | 892 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 8.50e-61 | 933 | 1091 | 22 | 180 | Chain C, NEDD8-conjugating enzyme Ubc12 [Homo sapiens] |
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| 2.12e-60 | 936 | 1091 | 5 | 160 | Chain A, Ubiquitin-conjugating enzyme E2 M [Homo sapiens] |
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| 7.47e-60 | 933 | 1091 | 25 | 183 | Structure of an RBX1-UBC12~NEDD8-CUL1-DCN1 complex: a RING-E3-E2~ubiquitin-like protein-substrate intermediate trapped in action [Homo sapiens],4P5O_I Structure of an RBX1-UBC12~NEDD8-CUL1-DCN1 complex: a RING-E3-E2~ubiquitin-like protein-substrate intermediate trapped in action [Homo sapiens] |
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| 1.81e-37 | 935 | 1090 | 27 | 188 | S. cerevisiae Ubc12 [Saccharomyces cerevisiae],3O2U_B S. cerevisiae Ubc12 [Saccharomyces cerevisiae] |
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| 9.81e-26 | 928 | 1072 | 5 | 158 | Chain A, NEDD8-conjugating enzyme UBE2F [Homo sapiens] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 0.0 | 1 | 860 | 1 | 908 | Chitin synthase 1 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=chs-1 PE=3 SV=2 |
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| 0.0 | 1 | 860 | 1 | 902 | Chitin synthase G OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=chsG PE=2 SV=2 |
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| 0.0 | 12 | 863 | 19 | 910 | Chitin synthase B OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=chsB PE=2 SV=2 |
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| 0.0 | 9 | 826 | 4 | 866 | Chitin synthase 3 OS=Exophiala dermatitidis OX=5970 GN=CHS3 PE=3 SV=2 |
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| 0.0 | 114 | 860 | 106 | 884 | Chitin synthase C OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=chsC PE=3 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | CS Position |
|---|---|---|
| 1.000054 | 0.000009 |
TMHMM Annotations download full data without filtering help
| Start | End |
|---|---|
| 559 | 581 |
| 614 | 636 |
| 651 | 673 |
| 694 | 716 |
| 794 | 813 |
| 834 | 856 |