CAZyme Information: FGRAMPH1_01T27963-p1

Basic Information

• Species: Fusarium graminearum
• Lineage: Ascomycota; Sordariomycetes; ; Nectriaceae; Fusarium; Fusarium graminearum
• CAZyme ID: FGRAMPH1_01T27963-p1
• CAZy Family: GT8
• CAZyme Description: cellobiose dehydrogenase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
838		90369.66	6.8039

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_FgraminearumPH-1	14145	229533	2	14143

• Gene Location: location=HG970335:7618803-7621737(+)

Full Sequence      

MVSFRSSWLLAIASLTQYVAGQQSAPTSLTDANTGIIFDTWKAPSMTFGFTFPADGQTTN
ADEFIGYLNCATPKGKSTGWCGLSYGGSMTNSLLLFAYPHDGEILTTFHWASAQVEPVQY
KGKATLTQISSKITDDGFTLIYRCQGCTSWSQDGSSGRLATTSTVAVLGWAHSLTNAINP
ECPAEARMLQHETQSIFGGQLTSNAFNSKYADWAKLATKVVKGDCDGSEPTATATGEPTP
TAEPTGNPVPNETYDYVVVGGGAGGLPIADRLSEAGKKVLLIEKGPPSTGRWGGTRKPDW
LKGTDLTRFDVPGLCNQLWVDSAGIACPDTDQMAGCVLGGGTAVNAGLWWRPTPEDWDYN
FPDGWKAKDMAKYEQRVFSRIPGTMVPSMDGKLYLDQGFKVVAGALNKAGWGEVNALKEP
TAKNHTYTHPPFMFSGGERGGPLATYLVSASKRNNFKLWTNTQVRRLVRSGGHVTGLEVE
PFAGSGYAGTVKLTPETGRVILAAGTFGSAKILLRSGIGPEDQLDIVSKSSRDGSSMIKK
DQWINLPVGYNLEDHTNTDAVIKHPDVVFYDFYEAWDTPNAGDKSKYLDARSGILAQAAP
NIGPIIFDEIRGADNRVRSMQWTARVEASLGENDTKAMTLSQYLGRGAKSRGRMTITSAL
NTVVSGNPFLNDPEDKKAVVKALDNLRKALSGVKDLVWLQPAPSVSSQQYVDDMVVSWSN
RRANHWIGTNKMGKDDGRQGGTAVVDLNTKVYGTDNLFITDASIFPGMVTTNPSAYFVTA
SEKASDAILALPVSKAQEPYKQCGGTEWNGSMQCGKGYYCKALNPFYGQCYPEVSYIG

Enzyme Prediction     

EC	1.1.99.18:13	1.1.99.18:13

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
AA3	241	791	5e-248	0.9908759124087592
AA8	30	213	1.1e-57	0.989010989010989

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
406418	CDH-cyt	5.73e-58	30	209	2	177	Cytochrome domain of cellobiose dehydrogenase. CDH-cyt is the cytochrome domain, at the N-terminus, of cellobiose dehydrogenase. CDH-cyt folds as a beta sandwich with the topology of the antibody Fab V(H) domain and binds iron. The haem iron is ligated by Met83 and His181 in UniProtKB:Q01738.
225186	BetA	5.44e-48	268	790	22	535	Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only].
187688	CDH_like_cytochrome	7.42e-37	28	201	1	168	Heme-binding cytochrome domain of fungal cellobiose dehydrogenases. Cellobiose dehydrogenase (CellobioseDH or CDH) is an extracellular fungal oxidoreductase that degrades both lignin and cellulose. Specifically, CDHs oxidize cellobiose, cellodextrins, and lactose to corresponding lactones, utilizing a variety of electron acceptors. Class-II CDHs are monomeric hemoflavoenzymes that are comprised of a b-type cytochrome domain linked to a large flavodehydrogenase domain. The cytochrome domain of CDH and related enzymes, which this model describes, folds as a beta sandwich and complexes a heme molecule. It is found at the N-terminus of this family of enzymes, and belongs to the DOMON domain superfamily, a ligand-interacting motif found in all three kingdoms of life.
398739	GMC_oxred_C	4.43e-23	649	784	2	143	GMC oxidoreductase. This domain found associated with pfam00732.
235000	PRK02106	4.62e-22	268	801	20	546	choline dehydrogenase; Validated

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CEF84725.1|AA3_1|AA8|CBM1	0.0	1	838	1	838
CZS74890.1|AA3_1|AA8|CBM1	0.0	1	838	1	838
QPC72185.1|AA3_1|AA8|CBM1	0.0	1	833	1	833
CEI70537.1|AA3_1|AA8|CBM1	0.0	1	833	1	836
QKD55357.1|AA3_1|AA8|CBM1	0.0	1	834	1	837

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4QI7_A	0.0	24	830	2	805	Cellobiose dehydrogenase from Neurospora crassa, NcCDH [Neurospora crassa OR74A],4QI7_B Cellobiose dehydrogenase from Neurospora crassa, NcCDH [Neurospora crassa OR74A]
4QI6_A	0.0	24	830	3	806	Chain A, Cellobiose dehydrogenase [Thermothelomyces myriococcoides]
4QI4_A	3.05e-276	253	830	7	584	Chain A, Cellobiose dehydrogenase [Thermothelomyces myriococcoides],4QI5_A Chain A, Cellobiose dehydrogenase [Thermothelomyces myriococcoides]
1NAA_A	1.16e-119	254	791	3	537	Chain A, Cellobiose dehydrogenase [Phanerodontia chrysosporium],1NAA_B Chain B, Cellobiose dehydrogenase [Phanerodontia chrysosporium]
1KDG_A	1.34e-119	254	791	8	542	Chain A, cellobiose dehydrogenase [Phanerodontia chrysosporium],1KDG_B Chain B, cellobiose dehydrogenase [Phanerodontia chrysosporium]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q01738|CDH_PHACH	1.84e-145	19	791	15	769	Cellobiose dehydrogenase OS=Phanerodontia chrysosporium OX=2822231 GN=CDH-1 PE=1 SV=1
sp|Q47944|SDH_GLUOY	7.66e-24	254	788	5	527	L-sorbose 1-dehydrogenase OS=Gluconobacter oxydans OX=442 PE=3 SV=1
sp|E4QP00|HMFO_METS6	1.78e-22	254	789	6	528	5-(hydroxymethyl)furfural oxidase OS=Methylovorus sp. (strain MP688) OX=887061 GN=MPQ_0130 PE=1 SV=1
sp|B3PTE0|BETA_RHIE6	8.25e-22	255	800	4	539	Oxygen-dependent choline dehydrogenase OS=Rhizobium etli (strain CIAT 652) OX=491916 GN=betA PE=3 SV=1
sp|Q1MJU4|BETA_RHIL3	2.57e-21	255	800	4	539	Oxygen-dependent choline dehydrogenase OS=Rhizobium leguminosarum bv. viciae (strain 3841) OX=216596 GN=betA PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.000255	0.999706	CS pos: 21-22. Pr: 0.9772

TMHMM  Annotations     

There is no transmembrane helices in FGRAMPH1_01T27963-p1.